CAS: 103766-25-2; 5-Chloro-4-Hydroxypyridin-2(1H)-One

相似化合物

1379260-15-7 626-03-9 4214-79-3

上下游产品

CAS号2678-54-8 1,1-二乙氧基乙烯 | CAS号103792-80-9 3,5-dichloro-4-... | CAS号856850-46-9 2,4-diethoxy-5-... | CAS号856851-45-1 4-氯-2-乙氧基吡啶 | CAS号857991-71-0 4,5-二氯-2-乙氧基吡啶 | CAS号405230-82-2 2,5-二氯-4-氨基吡啶 | CAS号103766-97-8 (5-chloro-2-oxo... | CAS号155131-51-4 2-benzoyloxy-5-... | CAS号103815-09-4 2,4-dibenzoylox... | CAS号55934-01-5 2,4,5-三氯吡啶

3,5-Dichloro-2,4-Dimethoxypyridine置于盐酸,水,溶剂黄146,Sodium Iodide体系中,用 乙腈 用作溶剂,化学反应 14.0H,反应生成吉莫斯特
参考文献:吉美嘧啶的便捷合成
标题:吉美嘧啶的便捷合成
摘要:描述了一种实用的三步合成方法,总产率为 68%,使用 2,4-二甲氧基吡啶作为起始原料,使用 3,5-二氯-2,4-二甲氧基吡啶和 3,5-二氯-2,4-二羟基吡啶作为中间体.该方法的优点是反应步骤短,操作简单,收率好.
Doi:10.3184/174751918X15166150010920

专利信息

专利号:US-2022118123-A1
优先权日:2019-02-22
标 题 :Combination of ar antagonists and targeted thorium conjugates
发明人：HAMMER STEFANIE; HAGEMANN URS BEAT; HAENDLER BERNARD; LEJEUNE PASCALE; ZITZMANN-KOLBE SABINE; SCHATZ CHRISTOPH; KARLSSON JENNY
权利人:BAYER AG; BAYER AS
摘要:The present invention covers combinations of at least two components, component A and component B, comprising component A being PSMA-TTC, and component B being an antiandrogen selected form AR antagonists such as from cyproterone acetate, bicalutamide, flutamide, nilutamide, enzalutamide, apalutamide, darolutamide or keto-darolutamide, or an AR degrader such as ARV-110, or an ARN-terminal domain binder such as EPI-506, or an antisense oligonucleotide that reduces AR expression such as EZN-4176 or AZD-5312, or an androgen synthesis inhibitor such as abiraterone, particularly abiraterone acetate, seviteronel, galeterone, orteronel or ketoconazole, or a dual AR antagonist and androgen synthesis inhibitor such as ODM-204. Another aspect of the present invention covers the use of such combinations as described herein for the preparation of a medicament for the treatment or prophylaxis of a disease, particularly for the treatment of a hyper-proliferative disease.

专利号:CN-105920602-B
优先权日:2016-06-28
标 题:Application of NF-kappa B p65/HMGCS2 regulation pathway in preparation of medicine for regulating synthesis of ketone body

专利号:CN-103435566-A
优先权日:2013-08-22
标题 :A kind of synthesis technique for preparing potassium oxonate

专利号:CN-112916048-A
优先权日:2019-12-05
标 题:A kind of vanillin synthesis catalyst and preparation method thereof

专利号:CN-112916048-B
优先权日:2019-12-05
标 题 :A kind of vanillin synthesis catalyst and preparation method thereof