CAS: 57794-08-8; (1S,2S)-Cyclohexane-1,2-Diol

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1460-57-7 1792-81-0 1072-86-2

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CAS号286-20-4 环氧环己烷 | CAS号1460-57-7 反式-1,2-环己二醇 | CAS号98-88-4 苯甲酰氯 | CAS号765-87-7 1,2-环己二酮 | CAS号1225376-11-3 1,2-cyclohexane... | CAS号5011-76-7 ACETIC ACID 6-O... | CAS号100-09-4 对甲氧基苯甲酸 | CAS号64-19-7 冰醋酸 | CAS号65-85-0 苯甲酸 | CAS号1072-21-5 己二醛

合成工艺路线路线简述

    📜Trans-1,2-Cyclohexandiol 以 水 作为反应溶剂,化学反应 120.0H,以50%的收率获得产物(1S,2S)-反式-1,2-环己二醇
    参考文献:Preparation Of Optically Active Cyclohexanediols And (+)-α-Hydroxycycloheptanone By An Enzyme Catalysed Stereoinversion/oxidation Process
    标题:Preparation Of Optically Active Cyclohexanediols And (+)-α-Hydroxycycloheptanone By An Enzyme Catalysed Stereoinversion/oxidation Process
    摘要:研究发现,(+/-)-顺式和反式环己烷-1,2-二醇在与菌株cassia黄单胞菌共培养时,会发生双立体翻转过程,最终反应生成反式的(S,S)-环己烷-1,2-二醇.
    DOI:10.1016/s0040-4039(00)76545-2

    海关参考信息

    专利信息


    专利号:US-8487094-B2
    优先权日:2008-07-25
    标题 :Synthesis of inhibitors of 11β-hydroxysteroid dehydrogenase type 1
    发明人:FANDRICK KEITH R; GAO JOE JU; LI WENJIE; LU ZHI-HUI; ZHANG YONGDA
    权利人:FANDRICK KEITH R; GAO JOE JU; LI WENJIE; LU ZHI-HUI; ZHANG YONGDA; BOEHRINGER INGELHEIM INT
    摘要:Disclosed are syntheses of 11β-HSD1 inhibitors and corresponding intermediates that are promising for the treatment of a variety of disease states including diabetes, metabolic syndrome, obesity, glucose intolerance, insulin resistance, hyperglycemia, hypertension, hypertension-related cardiovascular disorders, hyperlipidemia, deleterious gluco-corticoid effects on neuronal function (e.g. cognitive impairment, dementia, and/or depression), elevated intra-ocular pressure, various forms of bone disease (e.g., osteoporosis), tuberculosis, leprosy (Hansen's disease), psoriasis, and impaired wound healing (e.g., in patients that exhibit impaired glucose tolerance and/or type 2 diabetes).

    专利号:US-9006347-B2
    优先权日:2011-09-08
    标 题 :Method of synthesising polycarbonates in the presence of a bimetallic catalyst and a chain transfer agent
    发明人:WILLIAMS CHARLOTTE K; KEMBER MICHAEL; BUCHARD ANTOINE; JUTZ FABIAN
    权利人:IMP INNOVATIONS LTD
    摘要:The invention provides a process for the synthesis of a polycarbonate, the process comprising the step of reacting carbon dioxide with at least one epoxide in the presence of a catalyst of formula (I) and a chain transfer agent. The invention also provides a polymerization system for the copolymerization of carbon dioxide and at least one epoxide comprising a catalyst of formula (I) and a chain transfer agent, polycarbonates produced by the inventive process, a block copolymer comprising a polycarbonate produced by the inventive process, and a method of producing the block copolymer. The invention also relates to novel catalysts of formula (III).

    专利号:US-9051656-B2
    优先权日:2009-07-23
    标题 :Electrochemical synthesis of aryl-alkyl surfacant precursor
    发明人:BHAVARAJU SAI; KARANJIKAR MUKUND; CHITTA PALLAVI
    权利人:BHAVARAJU SAI; KARANJIKAR MUKUND; CHITTA PALLAVI; CERAMATEC INC
    摘要:An aryl-alkyl (R—Ar) hydrocarbon is prepared by an electrosynthesis process in an electrolytic cell having an alkali ion conductive membrane positioned between an anolyte compartment configured with an anode and a catholyte compartment configured with a cathode. An anolyte solution containing an alkali metal salt of an alkyl carboxylic acid and an aryl compound is introduced into the anolyte compartment. The aryl compound may include an alkali metal salt of an aryl carboxylic acid, an arene (aromatic) hydrocarbon, or an aryl alkali metal adduct (Ar − M + ). The anolyte solution undergoes electrolytic decarboxylation to form an alkyl radical. The alkyl radical reacts with the aryl compound to produce the aryl-alkyl hydrocarbon.

    专利号:WO-2016142952-A1
    优先权日:2015-03-10
    标 题:Process for preparation of vilazodone and its novel intermediates
    发明人:BHEMIREDDY SATYANARAYANA REDDY; YARAPATHI VENKAT REDDY; PAIDIMARLA V VARA PRASADA REDDY
    权利人:NOSCH LABS PRIVATE LTD
    摘要:The invention relates to process for preparation of Vilazodone and novel intermediates for synthesis of Vilazodone.

    专利号:US-8022235-B2
    优先权日:2007-06-01
    标 题 :Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use
    发明人:PINCHUK ANATOLY; WEICHERT JAMEY P; LONGINO MARC
    权利人:CELLECTAR INC
    摘要:The present invention discloses boronic acids and esters of phospholipid ether analogs and methods for their synthesis and use. The boronic acids and esters of phospholipid ether analogs described herein can be used in treating cancer and in particular can be used in conjunction with radiation therapy, such as external beam radiation therapy and neutron capture therapy to specifically target and kill cancer cells.

    专利号:US-10906033-B2
    优先权日:2016-03-28
    标题 :Synthesis and application of chiral substituted polyvinylpyrrolidinones
    发明人:HUA DUY H
    权利人:UNIV KANSAS STATE
    摘要:Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a metallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The CSPVP complexes can be used in asymmetric oxidation of diols, enantioselective oxidation of alkenes, and carbon-carbon bond forming reactions, for example. The CSPVP can also be complexed with biomolecules such as proteins, DNA, and RNA, and used as nanocarriers for siRNA or dsRNA delivery.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Amatore, M.; Aubert, C.; Malacria, M.; Petit, M., Science of Synthesis Knowledge Updates, (2012) 3, 109.
    摘要:Vashchenko, B. V.; Grygorenko, O. O., Science of Synthesis Knowledge Updates, (2021) 3, 350.
    摘要:Vashchenko, B. V.; Grygorenko, O. O., Science of Synthesis Knowledge Updates, (2021) 3, 345.
    摘要:Smith, A. D.; Woods, P. A., Science of Synthesis: Asymmetric Organocatalysis, (2012) 1, 561.
    摘要:Wohlgemuth, R., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 2, 550.
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