CAS: 41230-93-7; 5-Bromo-4-Methylpyridine-2,3-Diamine
该化合物是一种有机化合物,其特征是其有六人组成的芳香环,有氮气循环,该化合物的特点是一个溴原子和一个附属于丙烯环的甲基组,以及位于2和3位置的两个氨基组(-NH2),这些功能组的存在有助于其再活性和潜在应用于各种化学反应,包括核生殖替代和混合反应.溴原子是一个良好的离子组,而氨基组可以参与氢联结和作为核素循环.该化合物可能展示生物活动,使其对药用化学和药物开发具有兴趣,其溶剂和条件可能不同,因此必须谨慎地处理它,因为氨和卤化化合物具有潜在的毒性.
- 英文名称5-Bromo-4-Methylpyridine-2,3-Diamine
- 中文名称2,3-二氨基-5-溴-4-甲基吡啶
- IUPAC名称5-bromo-4-methylpyridine-2,3-diamine
- 其它别名5-溴-2,3-二氨基-4-甲基吡啶; 5-Bromo-4-Methyl-2,3-Pyridinediamine; 5-Bromo-2,3-Diamino-4-Methylpyridine; 5-Bromo-4-Methylpyridine-2,3-Diamine; 2,3-Pyridinediamine, 5-Bromo-4-Methyl-
- CAS编号41230-93-7
- MFCD编号:MFCD08062974
- EINECS号:963-212-0
- 分子式:C6H8BrN3分子量:202.05
- 产品CID: 1426730
- 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物
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MSDS等安全信息
欧盟法规
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📜5-溴-4-甲基-N-硝基吡啶-2-胺置于盐酸,硫酸,Tin(Ll) Chloride体系中,用 水 作为反应溶剂,化学反应 2.0H,反应生成 2,3-二氨基-5-溴-4-甲基吡啶
参考文献:Synthesis Of A 6-Methyl-7-Deaza Analogue Of Adenosine That Potently Inhibits Replication Of Polio And Dengue Viruses
标题:Synthesis Of A 6-Methyl-7-Deaza Analogue Of Adenosine That Potently Inhibits Replication Of Polio And Dengue Viruses
摘要:Bioisosteric Deaza Analogues Of 6-Methyl-9-Beta-D-Ribofuranosylpurine,A Hydrophobic Analogue Of Adenosine,Were Synthesized And Evaluated For Antiviral Activity. Whereas The 1-Deaza And 3-Deaza Analogues Were Essentially Inactive In Plaque Assays Of Infectivity,A Novel 7-Deaza-6-Methyl-9-Beta-D-Ribofuranosylpurine Analogue,Structurally Related To The Natural Product Tubercidin,Potently Inhibited Replication Of Poliovirus (Pv) In Hela Cells (Ic50 = 11 Nm) And Dengue Virus (Denv) In Vero Cells (Ic50 = 62 Nm). Selectivity Against Pv Over Cytotoxic Effects To Hela Cells Was > 100-Fold After Incubation For 7 H. Mechanistic Studies Of The 5'-Triphosphate Of 7-Deaza-6-Methyl-9-Beta-D-Riboluranosylpurine Revealed That This Compound Is An Efficient Substrate Of Pv Rna-Dependent Rna Polymerase (Rdrp) And Is Incorporated Into Rna Mimicking Both Atp And Gtp.
DOI:10.1021/jm100593S
海关参考信息
- 2933310010-吡啶
2939800000-其他生物碱 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:CA-2482705-A1
优先权日:2002-04-17
标题:Use of meglumine for inhibiting 3-deoxyglucosone synthesis in the skin
专利号:CA-2482705-C
优先权日:2002-04-17
标题 :Use of meglumine for inhibiting 3-deoxyglucosone synthesis in the skin
