CAS: 3796-63-2; 6,10,14,18-Tetramethylnonadeca-5,9,13,17-Tetraen-2-One

上下游产品

6,10,14-trimethyl-5,9,13-pentadecatriene-2-on sodium acetylide (4E,8E,12E)-ethyl 2-acetyl-5,9,13,17-tetramethyl°Ctadeca-4,8,12,16-tetraenoate (6E,10E)-geranyllinalool (E,E,E,E)-geranylfarnesoic acid geranylfarnesol

📜在 四丁基高碘酸铵,高碘酸体系中,用 二氯甲烷,水 用作溶剂,化学反应 48.0H,以23 Mg的收率获得(5E,9E,13E)-6,10,14,18-四甲基十九碳-5,9,13,17-四烯-2-酮
参考文献:聚异戊二烯的位置选择性环氧化策略
标题:聚异戊二烯的位置选择性环氧化策略
摘要:基于使用内部控制元件进行分子内反应,已开发出一种有效的策略,用于聚烯烃类异戊二烯醇的有效位点选择性环氧化.该方法通过应用于一系列底物浓度为 0.5 Mm 的聚异戊二烯醇(聚异戊二烯醇)来说明.对于在一个末端具有羟基官能团的聚异戊二烯醇底物,内部环氧化作用可针对聚异戊二烯醇的双键,该双键距末端羟基异戊二烯亚单元四或五处.
Doi:10.1021/ja801899V

专利信息

专利号:US-9981935-B2
优先权日:2013-07-05
标 题:Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of acids
发明人：MEDLOCK JONATHAN ALAN; LETINOIS ULLA; NETSCHER THOMAS; BONRATH WERNER
权利人:DSM IP ASSETS BV
摘要:The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of a specific type and of at least one Bransted acid or in the presence a specific chiral compound having a Bransted acid functional group in the molecule.

专利号:US-9815809-B2
优先权日:2013-07-05
标题:Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of phenols or thiophenols
发明人：LETINOIS ULLA; NETSCHER THOMAS
权利人:DSM IP ASSETS BV
摘要:The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific type and of at least one phenol or thiophenol.

专利号:US-9809565-B2
优先权日:2013-07-05
标 题 :Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of ureas or thioureas
发明人：LETINOIS ULLA; NETSCHER THOMAS; ACKERMANN STEPHAN
权利人:DSM IP ASSETS BV
摘要:The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific type and of at least one urea or thiourea.

专利号:US-2004249219-A1
优先权日:2000-07-05
标题 :Method of making teprenone
发明人：SAUCY GABRIEL G
摘要:The invention is directed to an efficient and economical method of making teprenone. Teprenone is synthesized by converting geranylgeraniol to teprenone by a novel route. The method of synthesis can begin with geranylgeraniol obtained from a biological source such as fermentation of a microorganism capable of producing geranylgeranyl or enzymatic synthesis in a cell free system to produce predominantly the 5E isomer of teprenone. The chemical synthesis proceeds with retention of configuration such that the teprenone produced has the isomeric configuration of the geranylgeraniol starting material.

专利号:WO-2014018862-A1
优先权日:2012-07-27
标 题 :Pharmaceutical compositions comprising a heat shock protein inhibitor and a; purine de novo synthesis inhibitor for treating rheumatoid arthritis or cancer
发明人：FANG YE
权利人:CORNING INC; FANG YE
摘要:A pharmaceutical composition including an effective amount of the combination of: an heat shock protein (HSP) inhibitor, and a purine de novo biosynthesis inhibitor, or a pharmaceutically acceptable salt thereof. Also disclosed is a method of treating rheumatoid arthritis or cancer including administering an effective amount of the above mentioned pharmaceutical composition to a patient in need of such treatment, as defined herein.

专利号:US-3939202-A
优先权日:1973-01-31
标题:Process for preparing polyene compounds
发明人：MATSUI MASANAO; KITAMURA SEIICHI; MORIOKA MASAHIRO
权利人:TEIKOKU CHEM IND CO LTD
摘要:Polyene compounds of the formula: ##EQU1## wherein R' is protected or unprotected hydroxyl or a group of the formula: ##EQU2## (in which R' and R'' are each carboxyl or a group convertible into carboxyl on hydrolysis), m is a positive integer and n is 0 or a positive integer, which are useful as intermediates in the synthesis of coenzyme Q, can be produced advantageously through a step for the dehydration of a compound of the formula: ##EQU3## wherein R', m and n are each as defined above.