CAS: 16136-52-0; 4-Cyanoindole

相似化合物

1074-86-8 2124-55-2 15861-36-6

上下游产品

CAS号25235-85-2 4-氯吲哚 | CAS号557-21-1 氰化锌 | CAS号88059-19-2 2-cyano-6-nitro... | CAS号81038-39-3 4-cyano-1-metho... | CAS号75266-12-5 1,3-diazabenzo[... | CAS号110811-33-1 4-cyano-1H-indo... | CAS号24621-73-6 4-氯-2-甲酸 | CAS号83-42-1 2-氯-6-硝基甲苯 | CAS号36892-19-0 Benzenepropanoi... | CAS号78283-23-5 1-hydroxy-4-nit... | CAS号105907-63-9 4-氰基芦竹碱 | CAS号3468-18-6 4-(氨甲基)吲哚 | CAS号39830-66-5 吲哚-4-羧酸甲酯 | CAS号628711-58-0 1-甲基-1H-吲哚-4-甲腈 | CAS号3377-71-7 1-苄基吲哚 | CAS号1074-86-8 4-吲哚甲醛 | CAS号1186663-64-8 3-溴-4-氰基吲哚 | CAS号133994-99-7 1-甲基-1H-吲哚-4-甲醛 | CAS号177548-00-4 1-苄基-1H-吲哚-4-甲腈 | CAS号2124-55-2 吲哚-4-羧酸

4-氰基吲哚-3-甲醛置于吡啶,Sodium Chlorite,2-甲基-丁烯体系中,化学反应生成4-氰基吲哚
参考文献:Yamada,Fumio; Somei,Masanori,Heterocycles,1987,Vol. 26,# 5,P. 1173-1176
标题:Yamada,Fumio; Somei,Masanori,Heterocycles,1987,Vol. 26,# 5,P. 1173-1176

专利信息

专利号:US-9969686-B2
优先权日:2014-08-05
标 题 :Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them
发明人：TANG WEIPING; LI XIAOXUN; SHU DONGXU; WINSTON-MCPHERSON GABRIELLE N
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Described is a method to make diindolylmethanes and indolyl/pyrrolylmethanes, The method includes the steps of contacting an ether comprising an arylpropargyl moiety and an amine-protected, substituted or unsubstituted aniline moiety with a substituted or unsubstituted indol or a substituted or unsubstituted pyrrole, in the presence of a metal-containing catalyst, for a time and at a temperature to cause an annulation/arylation cascade reaction that yields a diindolylmethane or a indolyl/pyrrolylmethane. The resulting compounds are effective to modulate activity of arylhydrocarbon receptors, to inhibit activity of PCSK9, and to stimulate secretion of glucagon-like peptide 1 in mammals.

专利号:US-10752927-B2
优先权日:2018-03-01
标 题 :Method for the synthesis of tryptophan analogs in aqueous solvents at reduced temperatures
发明人：BOVILLE CHRISTINA E; ROMNEY DAVID K; ALMHJELL PATRICK J; SIEBEN MICHAELA M
权利人:CALIFORNIA INST OF TECHN
摘要:The present disclosure provides methods for preparing tryptophans and tryptophan derivatives. The methods include: combining i) an indole substrate or azulene substrate, ii) a serine substrate, and iii) an engineered tryptophan synthase β-subunit (TrpB); and maintaining the resulting mixture under conditions sufficient to form the product compound. The engineered TrpB comprises a PLP binding loop mutation, a helix 1 mutation, a strand 7-8 mutation, or a combination thereof. New TrpB variants are also described.

专利号:WO-0053313-A2
优先权日:1999-03-09
标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries

专利号:US-2019271016-A1
优先权日:2018-03-01
标题:Method for the synthesis of tryptophan analogs in aqueous solvents at reduced temperatures

专利号:US-2016039754-A1
优先权日:2014-08-05
标题 :Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them

专利号:US-2018222861-A1
优先权日:2014-08-05
标题:Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them