CAS: 16019-33-3; 2-(4,6-Dichloropyrimidin-5-yl)Acetaldehyde

相似化合物

171096-33-6 853680-74-7 16019-31-1

上下游产品

5-allyl-4,6-dichloropyrimidine 5-(prop-2-en-1-yl)pyrimidine-4,6-diol (2-propenyl)propanedioic acid diethyl ester 5-allyl-6-hydroxy-3H-pyrimidin-4-one 4,6-dichloro-5-(2,2-diethoxyethyl)pyrimidine 7-(4-bromo-3-fluorophenyl)-4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine 2-(4,6-dichloropyrimidin-5-yl)ethanol H-pyrrolo[2,3-d]pyrimidine4-chloro-7-(3-methoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidine

烯丙基丙二酸二乙酯置于四氧化锇,乙醇,Sodium,N-甲基吗啉氧化物,三氯氧磷体系中,用 1,4-二氧六环,水 用作溶剂,化学反应 32.0H,反应生成4,6-二氯嘧啶-5-乙醛
参考文献: Cyclolic Hydrazine Derivatives As Hiv Attachment Inhibitors[fr] Dérivés D'Hydrazine Cycliques En Tant Qu'Inhibiteurs De Fixation Du Vih
标题: Cyclolic Hydrazine Derivatives As Hiv Attachment Inhibitors[fr] Dérivés D'Hydrazine Cycliques En Tant Qu'Inhibiteurs De Fixation Du Vih
摘要:提供了公式i的化合物,包括其药用可接受的盐:其中a选自以下组:其中z选自以下组:这些化合物可用作hiv附着抑制剂.

专利信息

专利号:US-9278939-B2
优先权日:2013-09-18
标 题:Methods for preparation of (4,6-dihalo-pyrimidin-5-yl)-acetaldehydes
发明人：LU SHAOPO; LI ZHUOCAI
权利人:SUZHOU JONATHAN NEW MATERIAL TECHNOLOGY CO LTD
摘要:This invention relates to the synthesis of chemical compounds and particularly to methods for the preparation of (4,6-dihalo-pyrimidin-5-yl)-acetaldehydes. The methods involve preparing a compound of the following general formula V from a compound of the following general formula IV through hydrolysis under the action of mercury dichloride and calcium carbonate, according to the following equation: n nwherein X is Cl or Br. The methods offer the benefits of use of highly available materials, high step yields, moderate reaction conditions, simply post-processing and purification, and suitability to industrialized production.

专利号:WO-2009042013-A1
优先权日:2007-08-02
标题:Process for the synthesis of e1 activating enzyme inhibitors

专利号:US-2018079755-A1
优先权日:2007-08-02
标 题:Process for the synthesis of e1 activating enzyme inhibitors

专利号:US-2009036678-A1
优先权日:2007-08-02
标题 :Process for the synthesis of E1 activating enzyme inhibitors

专利号:US-2015080573-A1
优先权日:2007-08-02
标题 :Process for the synthesis of e1 activating enzyme inhibitors

专利号:EP-2546256-A2
优先权日:2007-08-02
标 题 :Process for the synthesis of intermediates compounds useful for the preparation of E1 activity activating enzyme inhibitors