CAS: 1035654-66-0; Sarecycline

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合成工艺路线路线简述

  • 合成目标产物 Fosravuconazole Bis(L-Lysine 主要起始原料 Are-001 And N,O-Dimethylhydroxylamine Hydrochloride
  • (文献来源)合成步骤主要原料 Are-001 和 N,O-Dimethylhydroxylamine Hydrochloride

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专利信息


专利号:PT-117254-B
优先权日:2021-05-26
标题 :METHOD FOR SYNTHESIS OF 9-AMINOMETHYL TETRACYCLINE COMPOUNDS

专利号:US-11980627-B2
优先权日:2019-06-14
标 题 :Triple pharmaceutical composition for proteinaceous infection
发明人:ATIBA JOSHUA O
权利人:ATIBA JOSHUA O
摘要:There are disclosed therapies and preventions of prion protein complex infections. The transcription of the amyloid precursor protein gene and PrP gene and the RNA transcript are the rate-limiting steps and are most susceptible for blockage and control of the process of amyloid protein formation and PrP sc formation. Thus, therapies and prevention regimes for prion protein complex infections interrupt this process at the level of DNA transcription to RNA, RNA transport to the mitochondrion for protein synthesis and deposition in the cerebral cortex neurons.

专利号:CN-117616008-A
优先权日:2021-05-26
标题 :Synthesis method of 9-aminomethyl tetracycline compound

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主要参考文献


1: Kaul G, Saxena D, Dasgupta A, Chopra S. Sarecycline hydrochloride for the treatment of acne vulgaris. Drugs Today (Barc). 2019 Oct;55(10):615-625. doi: 10.1358/dot.2019.55.10.3045040. Review. Available from http://www.ncbi.nlm.nih.gov/books/NBK548293/ doi: 10.1016/j.japh.2019.07.016. doi: 10.2217/fmb-2019-0199. Epub 2019 Sep 2.
5: Haidari W, Bruinsma R, Cardenas-de la Garza JA, Feldman SR. Sarecycline Review. Ann Pharmacother. 2019 Aug
28:1060028019873111. doi: 10.1177/1060028019873111. [Epub ahead of print] doi: 10.1007/s40265-019-01122-z.
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