CAS: 922-32-7; N-Methyl-N-(N-Phosphonocarbamimidoyl)Glycine, Disodium Salt

• 英文名称N-Methyl-N-(N-Phosphonocarbamimidoyl)Glycine, Disodium Salt
• 中文名称磷酸肌酸二钠盐
• IUPAC名称sodium (N-(carboxymethyl)-N-methylcarbamimidoyl)phosphoramidate
• 其它别名2-[methyl-(N'-Phosphonatocarbamimidoyl)Amino]Acetic Acid ; Disodium [(E)-{amino[(Carboxymethyl)(Methyl)Amino]Methylidene}Amino]P
• CAS编号922-32-7
• MFCD编号:MFCD00014351
• EINECS号:213-074-6
• FDA UNII编号:79577SJY6E
• 分子式:C4H8N3Na2O5P
• 分子量:255.08
• 产品CID: 1960016
• 产品分类生物化工 → 氨基酸及其衍生物 → 氨基醇类衍生物

• 相似结构搜索
• InChIKey: RNTXMYSPASRLFT-UHFFFAOYSA-L
• InChI=1S/C4H10N3O5P.Na/c1-7(2-3(8)9)4(5)6-13(10,11)12;/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12);/q;+1/p-1…
• 计算化学: 氢键受体数6.0氢键供体数4.0可旋转键数4.0

物理性质

• 闪点268.5 °C
• 密度1.784 at 20°C
• PH:pH : 8.3 (20% in water)
• PSA:149.42
• LogP:-1.17 at 22°C and pH7
• 蒸汽压0.025Pa at 20-50°C
• 溶解性水: 0.1 G/ml, Clear, Colorless
• 敏感性常温常压下稳定，
• 外观形态白色粉末
• 储存条件惰性气氛,2-8°C
• 产品应用药品及保健品添加剂.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别急性毒性 类别4(吸入)
  急性毒性 类别4(经皮)
  急性毒性 类别4(经口)
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
• 警示词Warning(警告)
• 危险描述H332 |吸入有害.
  H312 |皮肤接触有害.
  H302 |吞咽有害.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
• 防范说明P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362
• 危险品标志Xn
• 安全声明22-24/25-36-26
• 危险类别码20/21/22-36/37/38
• WGK Germany3

欧盟法规

合成工艺路线路线简述

• 6020-87-7 = 922-32-7
  反应条件:1.1 Reagents: Sodium Hydroxide Catalysts: N-Methyl-L-Proline Solvents: Water1.2 Reagents: Sodium Hydroxide,Phosphorus Oxychloride Solvents: Water; 8 °C; 1 H,8 °C1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 9.5
  标题:Disodium Creatine Phosphate Compound And Preparation Method Thereof
  参考文献:China]
  
  25221-53-8 = 922-32-7
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Water; 0 °C; 30 Min,0 °C; 0 °C -> 45 °C; 16 H,45 °C; 45 °C -> 10 °C1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 8
  标题:Preparation Method Of High-Content Creatine Phosphate Disodium Salt
  参考文献:China]
  
  107-97-1 + 876507-38-9 = 922-32-7
  反应条件:1.1 Solvents: Water; 20 - 25 °C; 8 H,25 - 30 °C1.2 Reagents: Sodium Hydroxide Solvents: Water; Ph 8 - 9
  标题:Method For Preparation Of Creatine Phosphate Sodium For Treating Cardiovascular Diseases
  参考文献:China]
  
  855158-73-5 = 922-32-7
  反应条件:1.1 Reagents: Hydrogen Catalysts: Platinum Dioxide Solvents: Ethanol; 24 H,Rt1.2 Reagents: Sodium Hydroxide Solvents: Water; 5 Min,Cooled1.3 Reagents: Sodium Hydroxide Solvents: Water; 24 H,Rt1.4 Reagents: Hydrochloric Acid Solvents: Water; Ph 7.8,Cooled
  标题:Synthesis Of Phosphocreatine Disodium
  作者:Tang,Lei; Wang,Jianta; Zhu,Gaofeng
  参考文献:Zhongguo Yiyao Gongye Zazhi 日期:2009 卷标:40(3) 页码:172-173]
  
  60-27-5 = 922-32-7
  反应条件:1.1 Reagents: P,P,P′,P′-Tetrakis(Phenylmethyl) (Diphosphate),Tetrabutylammonium Chloride Solvents: Ethyl Acetate; Rt -> 0 °C; > 20 °C1.2 Reagents: Formic Acid Catalysts: Palladium Solvents: Methanol,Water; 10 H,Rt1.3 Reagents: Sodium Hydroxide Solvents: Water; Ph 12,Rt; 4 H,Rt -> 80 °C
  标题:Method For Producing Creatine Phosphate Sodium Using Tetrabenzyl Pyrophosphate
  参考文献:China]
  
  19604-05-8 = 922-32-7
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Water; Cooled; 12 H,Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 8.7,Cooled1.3 Reagents: Ethanol; 6 H,Rt
  标题:Synthesis Of Phosphocreatine Disodium
  作者:Lian,Meihua
  参考文献:Zhongguo Yiyao Gongye Zazhi 日期:2013 卷标:44(7) 页码:655-657]
  
  19604-05-8 = 922-32-7
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Water; 30 °C
  标题:Purification Method For Creatine Phosphate Sodium And Preparation Of Aseptic Powder
  参考文献:China]
  
  57-00-1 = 922-32-7
  反应条件:1.1 Solvents: Acetonitrile; Rt -> 10 °C1.2 Reagents: Diisopropylethylamine; 10 °C; 10 °C -> 0 °C1.3 Reagents: Phosphorus Oxychloride; 30 S,0 °C; 60 H,0 °C -> Rt; 50 °C; 50 °C -> Rt1.4 Reagents: Sodium Hydroxide Solvents: Water; 1 H,Rt
  标题:Synthesis Of Sodium Phosphocreatine
  参考文献:China]
  
  98924-69-7 = 922-32-7
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Ethanol,Water; Rt1.2 Reagents: Hydrogen Catalysts: Palladium (Carbon Supported); Rt1.3 Reagents: Ethanol Solvents: Water; Rt; 4 - 6 H,Rt
  标题:Method For Synthesis Of Phosphocreatine Disodium Salt
  参考文献:China]
  
  57-00-1 = 922-32-7
  反应条件:1.1 Reagents: Phosphoric Acid Solvents: Ethanol; 3 H,Rt1.2 Reagents: 2,6-Lutidine,Dicyclohexylcarbodiimide Catalysts: 4-(Dimethylamino)Pyridine Solvents: Ethyl Acetate; 3 H,Reflux1.3 Reagents: Sodium Hydroxide Solvents: Water; 3 H,Rt
  标题:Synthesis Process Of Sodium Creatine Phosphate
  参考文献:China

海关参考信息

• 2912110000-甲醛
  2912120000-乙醛
  2915110000-甲酸
  2915211900-乙酸
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

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• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
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