CAS: 86-93-1; 1-Phenyl-1H-Tetrazole-5(2H)-Thione

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CAS号103-72-0 异硫氰酸苯酯 | CAS号65753-93-7 N-甲基-2-二甲氨基乙酰氧肟酸 | CAS号84598-74-3 3-((1-phenyl-1H... | CAS号13078-30-3 N-苯基-1,2,3,4-三噻唑-5-胺 | CAS号32276-00-9 bis[(1-phenylte... | CAS号95-54-5 邻苯二胺(OPD) | CAS号95-55-6 邻氨基苯酚 | CAS号95-85-2 2-氨基-4-氯苯酚 | CAS号16867-03-1 2-氨基-3-羟基吡啶 | CAS号5351-69-9 4-苯基-3-氨基硫脲 | CAS号5378-52-9 1-苯基-1H-四唑 | CAS号1455-92-1 5-甲硫基-1-苯基-1H-四氮唑 | CAS号1455-91-0 1-methyl-4-phen... | CAS号141717-63-7 2-[(1-phenyltet... | CAS号203317-33-3 5-pentylsulfony... | CAS号18233-34-6 5-bromo-1-pheny... | CAS号25746-68-3 5,5'-(Methylene... | CAS号25803-68-3 1-[硫代(1-苯-1H-四唑... | CAS号25746-67-2 1-Phenyl-2-[(1-... | CAS号5117-07-7 5,5-二硫-1,1-双苯基四氮唑

硫代异氰酸苯酯置于sodium Hydroxide,三(2-氯乙基)胺体系中,化学反应生成 1-苯基-5-巯基四氮唑
参考文献:亚硝酸与 4-取代基氨基脲的反应
标题:亚硝酸与 4-取代基氨基脲的反应
摘要:亚硝酸与 4-烷基-或 4-芳基-氨基硫脲的反应,以及烷基-或芳基-异硫氰酸酯与肼酸的反应,产生相同的 5-(取代)氨基-1,2,3,4-噻三唑.这是通过红外吸收和化学降解研究确定的.5-(取代)氨基-1,2,3,4-噻三唑与碱水溶液的反应导致两个竞争性反应:(1)降解为异硫氰酸盐和叠氮离子,以及(2)异构化为 1-取代-Tetrazole-5-Thiol,路径 (1) 或 (2) 的程度取决于取代基的性质.当取代基是烷基时,路径 (1) 占主导地位,而当取代基是芳基时,路径 (1) 和 (2) 都发生,相对比例取决于芳基的电学性质,路径(2)随着电负性的增加而增加.发现 1-芳基-四唑-5-硫醇在其熔点下是热不稳定的,或多或少地剧烈降解为 1 摩尔比例的纯镍.
DOI:10.1139/v57-116

专利信息

专利号:US-6159673-A
优先权日:1996-07-17
标 题:Oxonol compound, light-sensitive material and process for the synthesis of oxonol compound
发明人：NISHIGAKI JUNJI; DEGUCHI YASUAKI
权利人:FUJI PHOTO FILM CO LTD
摘要:An oxonol compound is represented by the following formula (I): in which Z is an atomic group that forms a cyclic amide ring; each of W1 and W2 independently is an atomic group that forms an acidic nucleus ring; and M is a cation. Other oxonol compounds, a light-sensitive material containing an oxonol compound and a process for the synthesis of an oxonol compound are also disclosed.

专利号:EP-1473330-B1
优先权日:1996-07-17
标题:Process for the synthesis of oxonol compound
发明人：NISHIGAKI JUNJI; DEGUCHI YASUAKI
权利人:FUJI PHOTO FILM CO LTD
摘要:An oxonol compound is represented by the following formula (I): in which each of Z, W<1> and W<2> independently is an atomic group that forms a heterocyclic ring; and M is a cation. A process for the synthesis of an oxonol compound is disclosed.

专利号:US-4594426-A
优先权日:1980-01-17
标题 :Benzoxazole derivative intermediates for synthesis of dye releasing redox compounds
发明人：FUJITA SHINSAKU; KOYAMA KOICHI; INAGAKI YOSHIO
权利人:FUJI PHOTO FILM CO LTD
摘要:Benzoxazole derivatives represented by general formula (I) which are intermediates for synthesis of o-sulfonamidophenol derivatives useful as dye releasing redox compounds in a color diffusion transfer color image forming process: ##STR1## wherein R 1 and R 2 , which may be the same as or different from each other, each represents an alkyl group or an aryl group or they may combine and form a ring; R 3 represents a hydrogen atom, an alkyl group or an aryl group; R 4 represents an alkyl group or an aryl group; R 5 represents an alkyl group, an alkoxy group, an alkylthio group, an arylthio group, a halogen atom or an acylamino group, or --CR 1 R 2 R 3 and R 5 may combine and form the nucleus ##STR2## which is condensed at the 6- and the 7-positions of the benzoxazole nucleus; and n is 0, 1 or 2.

专利号:WO-2025082632-A1
优先权日:2023-10-16
标 题:Method and composition for oligonucleotide synthesis
发明人：SAITO MASAHARU
权利人:BACHEM HOLDING AG
摘要:The invention pertains to a method for the synthesis of oligonucleotides using pseudo solid-phase protecting groups, wherein said method comprises a step of subjecting a solution comprising a component (C-0)# to one or more aqueous extractions, wherein the organic phase comprises the component (C-0)#. Said component (C-0)# is a nucleoside or an oligonucleotide, which is covalently bonded to a pseudo solid-phase protecting group and comprises a free backbone hydroxyl group. The aqueous phase of each of said one or more aqueous extractions has a pH-value in the range of 4-7.

专利号:EP-4605403-A1
优先权日:2022-10-17
标 题:Method and composition for oligonucleotide synthesis
发明人：SAITO MASAHARU; TAKEDA KAZUTAKA; OKADA YOHEI; LUTHER ANATOL
权利人:BACHEM HOLDING AG
摘要:The invention pertains to methods for the synthesis of oligonucleotides using pseudo solid-phase protecting groups, wherein said method comprises at least one aqueous extraction carried out in the presence of one or more amide solvents SA, wherein each amide solvent SA is an amide solvent comprising one or more alkyl groups, wherein these one or more alkyl groups together comprise in total 6−24 carbon atoms. The invention further pertains to compositions comprising an oligonucleotide which is covalently bonded to a pseudo solid-phase protecting group and a mixed solvent comprising on or more of the aforementioned amide solvents SA.

专利号:WO-2024061842-A1
优先权日:2022-09-19
标 题:Improved oligonucleotide synthesis
发明人：CREUSEN GUIDO; MINUTH MARCO; SAMSON DANIEL
权利人:BACHEM HOLDING AG
摘要:A method for the solid-phase synthesis of a target oligonucleotide OT is disclosed, wherein said method comprises a step of incubating a nucleoside or oligonucleotide, which is covalently linked to a solid support and comprises a backbone hydroxyl moiety protected by a di(p-methoxyphenyl)phenylmethyl (DMT) protecting group, with a deprotection mixture, thereby cleaving said protecting group from said nucleoside or oligonucleotide, wherein said deprotection mixture is a liquid composition comprising a solvent, a protic acid having a pKa equal to or smaller than 4, and at least one alcohol of Formula (D), wherein in RD-1 R,D-2 R,D-3 RD-4 and RD-5 are indepently of each other selected from the group consisting of H, OH, a e1-e6-alkyl group, O(C1-C6-aIkyl), C(O)(Ci-C6-alkyl), C(O)O(Ci-C6-alkyl), F, Cl, Br, I, and CN. Such a method does not only suppress depurination, but also results in an acceptable product yield.