专利号:WO-2023199355-A1 优先权日:2022-04-12 标题 :A method for synthesis of nano plant nutrients 发明人:URVI RAJESH DEDHIA; PANDHARINATH BANSODE UMESH; MAHADEO GOLE ANAND 权利人:COROMANDEL INTERNATIONAL LTD 摘要:The present invention relates to a method for synthesis of nano plant nutrients and compositions thereof. More particularly, the present invention relates to method for synthesis of nano- plant nutrient composition comprising plant nutrient and natural polymers like chitosan for improving the bioavailability of macro and micronutrients to plants.
专利号:WO-2024236596-A1 优先权日:2023-05-15 标 题 :A process of synthesis of nano dap plant nutrient 发明人:DOSHI SIDDHARTH; DR MANKAD MOUNIL 权利人:A RAY NANO SCIENCE AND RESERCH CENTRE LLP 摘要:The present invention relates to the novel manufacturing process of nanostructured diammonium phosphate (DAP) composite plant nutrients and/or biomolecules using natural and/or synthetic polymers as an encapsulating agent More particularly, said invention provides novel production of nano DAP and its formulation through the utilization of natural as well as synthetic materials that multifunctionally act as reducing and stabilizing agents for the solubilization of commercially available DAP. Moreover, the present invention facilitates significant improvement of commercially available DAP through novel nano-structured DAP formulations for the growth and stability of plants under normal conditions.
专利号:US-2023407357-A1 优先权日:2022-05-20 标 题 :Biomanufacturing of oligosaccharides and derivatives from simple sugar 发明人:HOEPKER ALEXANDER CHRIS; CORGIE STEPHANE CEDRIC; SAVINO KEITH 权利人:ZYMTRONIX CATALYTIC SYSTEMS INC 摘要:The invention provides methods for glycosylation and preparation of compounds. The compounds include galactosylated, sialylated, fucosylated, and N-acetylglucosaminylated compounds from simple animal-derived, plant-derived, or microbe-derived oligosaccharides and sugars. In certain embodiments, the invention provides trinucleotide-free enzymatic production of oligosaccharides starting from simple sugars that include plant-based sugars. The invention also provides the enzymatic production of fucosylated oligosaccharides and fucosylated antibody-glycan conjugates from common sugars. The production may be a cell-free, one-pot synthesis using enzymes, and in some embodiments, immobilized enzymes. The synthesis is a highly customizable and highly efficient cell-free manufacturing process. In some embodiments, lactose derivatives and human milk oligosaccharides (HMOs) are produced.
专利号:US-2022340949-A1 优先权日:2021-04-16 标 题 :Methods of Isoprenoid Synthesis Using a Genetically Engineered Hydrocarbonoclastic Organism in a Biofilm Bioreactor 发明人:MAGYAR ANDREW P; ONDERKO ELIZABETH 权利人:CAPRA BIOSCIENCES INC 摘要:Described herein are genetically-engineered organisms comprising synthetic operons for the production of isoprenoids, carotenoids, and retinoids, optimized for use in a hydrocarbonoclastic organism, and methods for the synthesis and extraction of isoprenoids in a biofilm bioreactor comprising the genetically-engineered organisms.
专利号:US-2024132927-A1 优先权日:2020-12-02 标 题 :Modular glycan production with immobilized bionanocatalysts 发明人:CORGIE STEPHANE CEDRIC; HOEPKER ALEXANDER CHRIS 权利人:ZYMTRONIX CATALYTIC SYSTEMS INC 摘要:The invention provides modular cell-free de-novo synthesis of glycans with immobilized bionanocatalysts. The invention provides materials, and in particular, magnetic materials, for producing glycans of defined length and sequences using one or more enzymes that are immobilized within bionanocatalysts (BNCs) which in turn are embedded within scaffolds to control the synthesis in batch or continuous processes manufacturing. In some embodiments, the scaffolds are high magnetism and high porosity composite blends of thermoplastics or thermosets comprising magnetic particles that form powders. In some embodiments, Selective Laser Sintering (SLS) is used to design and produce objects via 3D printing by sintering composite magnetic powders. The modular flow cells may be mixed and matched for a highly customizable and highly efficient cell-free manufacturing process. In some embodiments the elementary and system modules provided by the invention are employed. In preferred embodiments, human milk oligosaccharides (HMOs) are produced.
专利号:US-2025243525-A1 优先权日:2022-06-24 标 题 :Biocatalytic manufacture of sugar nucleotides 发明人:HOEPKER ALEXANDER CHRIS; CILA MEGHA; GISKA FABIAN 权利人:ZYMTRONIX CATALYTIC SYSTEMS INC 摘要:The invention provides the production of sugar-nucleotides and the isolation of sugar-nucleotides. In some embodiments the production or isolation are accomplished under acidic conditions. The production is a cell-free synthesis using enzymes, including immobilized enzymes. They may be accomplished using a one-pot reaction protocol. The synthesis may be used as a highly customizable and highly efficient cell-free manufacturing process. In some embodiments, the sugar-nucleotides are used to prepare UDP-Gal, lactose derivatives, and human milk oligosaccharides (HMOs).
参考文献:10.1021/ac2008465 摘要:Yang X, Wang E. A Nanoparticle Autocatalytic Sensor for Ag+ and Cu2+ Ions in Aqueous Solution with High Sensitivity and Selectivity and Its Application in Test Paper. Anal. Chem. 2011 May 27;83(12):5005–11. doi: 10.1021/ac2008465. 参考文献:10.1038/nchembio.2285 摘要:Elshahawi SI, Cao H, Shaaban KA, Ponomareva LV, Subramanian T, Farman ML, Spielmann HP, Phillips GN, Thorson JS, Singh S. Structure and specificity of a permissive bacterial C-prenyltransferase. Nature Chemical Biology. 2017 Feb 06;13(4):366–8. doi: 10.1038/nchembio.2285. 参考文献:10.2116/analsci.21p267 摘要:Yue J, Wang W, Lv Q, Wang Z, Liu Y, Zhang Q. Bicomponent colorimetric probe based on carbon quantum dots and o-phenylenediamine for sensitive and selective Cu2+ sensing. Anal Sci. 2022 Feb;38(2):323–30. doi: 10.2116/analsci.21p267. 参考文献:10.1016/0165-1218(94)90119-8 摘要:Sarrif AM, Arce GT, Krahn DF, O'Neil RM, Reynolds VL. Evaluation of carbendazim for gene mutations in the Salmonella/Ames plate-incorporation assay: the role of aminophenazine impurities. Mutation Research/Genetic Toxicology. 1994 Apr;321(1-2):43–56. doi: 10.1016/0165-1218(94)90119-8.