CAS: 531-29-3; (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(4-((E)-3-Hydroxyprop-1-En-1-yl)-2-Methoxyphenoxy)Tetrahydro-2H-Pyran-3,4,5-Triol

上下游产品

UDP-glucose coniferol

📜在 Sodium Methylate体系中,用 甲醇 作为反应溶剂,化学反应生成 松苷
参考文献:愈创木脂酰脱氢聚合物的制备及抗肺癌活性分析
标题:愈创木脂酰脱氢聚合物的制备及抗肺癌活性分析
摘要:在本文中,在 β-葡萄糖苷酶和漆酶存在下,以针叶树素为底物合成了愈创木脂酰脱氢木质素聚合物 (G-Dhp).carbon-13核磁共振(13C-NMR)测定表明,G-Dhp的结构与银杏磨木木质素(mwl)较为相似,均含有β-O-4,β-5,β-1,β-β 和 5-5 个子结构.通过用不同的极性溶剂分类获得具有不同分子量的g-Dhp级分.生物活性测定表明,乙醚可溶性组分 (Dc2) 对 A549 肺癌细胞的抑制作用最强,Ic50 为 181.46 +/-28.01 μg/ml.使用中压液相色谱法进一步纯化 Dc2 级分.抗癌分析表明,来自 Dc2 的 D4 和 D5 化合物具有更好的抗肿瘤活性,Ic50 值分别为 61.54 +/-17.10 μg/ml 和 28.61 +/-8.52 μg/ml.加热电喷雾电离串联质谱 (Hesi-Ms) 结果表明,D4 和 D5 均为松柏醛的 β-5-连接二聚体,13C-NMR
DOI:10.3390/molecules28083589

专利信息

专利号:US-6372461-B1
优先权日:1998-09-18
标题 :Synthesis of vanillin from a carbon source
发明人：FROST JOHN W
权利人:DIRECTORS OPERATING MICHIGAN S
摘要:A bioengineered synthesis scheme for the production of vanillin from a carbon source is provided. The bioconversion methods of the present invention comprise the steps of microbe-catalyzed conversion of a carbon source to vanillic acid followed by enzyme-catalyzed reduction of the vanillic acid to produce vanillin. As shown in the synthesis scheme of FIG. 2, the microbe-catalyzed conversion step of the present invention requires five enzymes which are provided by a recombinant microbe. In a preferred embodiment, the recombinant microbe is Escherichia coli designed to cause dehydration of 3-dehydroshikimic acid and regioselective methylation of the resulting protocatechuic acid. The enzyme-catalyzed reduction step of the present invention comprises the reduction of vanillic acid to vanillin by aryl-aldehyde dehydrogenase.

专利号:US-7799906-B1
优先权日:2004-09-22
标题 :Compositions and methods for modulating lignin of a plant
发明人：ROTTMANN WILLIAM H; CONNETT MARIE B; BLOKSBERG LEONARD N; FORSTER RICHARD L
权利人:ARBORGEN LLC
摘要:Novel plant monolignol synthesis, monolignol transport, and lignin polymerization genes and polypeptides encoded by such genes are provided. These genes and polynucleotide sequences are useful regulating the lignification process and plant phenotype. Moreover, these genes are useful for expression profiling of plant monolignol synthesis, monolignol transport, and lignin polymerization genes. The invention specifically provides polynucleotide and polypeptide sequences isolated from Eucalyptus and Pinus.

专利号:US-5973228-A
优先权日:1997-07-24
标 题:Coniferin beta-glucosidase cDNA for modifying lignin content in plants
发明人：CARLSON JOHN E; DHARMAWARDHANA D PALITHA; DOUGLAS CARL J; ELLIS BRIAN E
权利人:UNIV BRITISH COLUMBIA
摘要:A cDNA molecule encoding coniferin beta-glucosidase is disclosed. This enzyme catalyzes one of the last steps in the synthesis of lignin in plants. Plants having modified lignin content may be produced by transformation with this cDNA (or parts of the cDNA), for example, in either sense or antisense orientation. The invention includes methods of altering-lignin content in plants using this cDNA, as well as transformed plants, such as conifers, having modified lignin content.

专利号:WO-0017319-A2
优先权日:1998-09-18
标题:Synthesis of vanillin from a carbon source

专利号:EP-1114173-A2
优先权日:1998-09-18
标题 :Synthesis of vanillin from a carbon source

专利号:CN-102618603-B
优先权日:2012-03-26
标 题 :Application of poplar glycosyltransferase PtGT2 in catalytic synthesis of phenylpropanoid glycosides