CAS: 35966-84-8; 5-Chloro-N-Methyl-2-Nitroaniline
该化合物是一种有机化合物,其芳香结构特征包括一个氯组,硝基化合物和一个有矿功能的组,该化合物的特点是在5个位置上用氯原子和2个位置上与硝基化合物交替的苯环,而该矿的氮原子被甲基化;这些功能组的存在具有具体的化学特性,例如,再活性增加,而且具有电子替代反应的潜力;硝基化合物以其电回生效应而著称,这可能影响该化合物的再活性和稳定性;此外,该金属组可参与氢联结,影响各种溶剂的溶解性;该化合物可用于各种用途,包括作为有机合成的中间体或用于染料和药品的生产;应当参考安全数据,因为具有类似结构的化合物可能具有毒性或环境危害.
- 英文名称5-Chloro-N-Methyl-2-Nitroaniline
- 中文名称5-氯-N-甲基-2-硝基苯胺
- IUPAC名称5-chloro-N-methyl-2-nitroaniline
- 其它别名5-氯-N-甲基-2-硝基苯胺; 5-氯-2-硝基-N-甲基苯胺; 5-Chloro-N-Methyl-2-Nitrobenzenamine
- CAS编号35966-84-8
- MFCD编号:MFCD00143455
- EINECS号:609-197-3
- 分子式:C7H7ClN2O2分子量:186.6
- 产品CID: 1368546
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
- 相似结构搜索
- 产品信息参考
;;; - InChIKey: YWJPRGWHZDSXML-UHFFFAOYSA-N
- InChI=1S/C7H7ClN2O2/c1-9-6-4-5(8)2-3-7(6)10(11)12/h2-4,9H,1H3
- 计算化学: 氢键受体数3.0氢键供体数1.0可旋转键数2.0
物理性质
MSDS等安全信息
欧盟法规
C&L通报REACH预注册上下游产品
3,4-dinitro-chlorobenzene methylamine methanol 3'-Chlor-5'-nitro-N-methyltoluanilid 5-Chlor-2-nitro-N-methyl-ameisensaeureanilid -N-methyl-ethyl-methyl-cyanessigsaeureamidN-5-Chlor-2-nitro-phenyl-N-methyl-ethyl-methyl-cyanessigsaeureamid -N-methyl-ethyl-methyl-cyanessigsaeureamid(R)-(-)-N-5-Chlor-2-nitro-phenyl-N-methyl-ethyl-methyl-cyanessigsaeureamid -N-methyl-ethyl-methyl-cyanessigsaeureamid(S)-(+)-N-5-Chlor-2-nitro-phenyl-N-methyl-ethyl-methyl-cyanessigsaeureamid合成工艺路线路线简述
📜2,6-二氯-3-硝基苯甲酸置于盐酸体系中,用 乙醇,水 作为反应溶剂,化学反应 2.0H,反应生成 5-氯-N-甲基-2-硝基苯胺
参考文献:Romanowski,Jacek; Eckstein,Zygmunt,Polish Journal Of Chemistry,1984,Vol. 58,# 1-3,P. 263-268
标题:Romanowski,Jacek; Eckstein,Zygmunt,Polish Journal Of Chemistry,1984,Vol. 58,# 1-3,P. 263-268
海关参考信息
- 2903919090-氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-6753347-B2
优先权日:1999-06-28
标题:Intermediates for the synthesis of benzimidazole derivatives and a process for the preparation thereof
发明人：KISHI NAOYUKI; NAKAMURA YOSHITAKA; ABE NARUMI; TAKEBAYASHI TOYONORI
权利人:SANKYO CO
摘要:This invention provides a process for the preparation of a benzimidazole derivative (I) or a pharmaceutically acceptable salt thereof, n wherein R 1 is C 1 -C 6 alkyl, C 1 -C 6 alkoxyl, etc., R 2 is C 1 -C 6 alkyl, and R 3 is hydrogen or a protecting group, which exhibits excellent hyopoglycemic action, said process comprising condensation of an amine derivative (III) with a carboxylic acid derivatives (II) to afford a compound (IV), followed by cyclization of compound (IV) in the presence of an acid.
专利号:US-2003199580-A1
优先权日:1999-06-28
标 题:Intermediates for the synthesis of benzimidazole derivatives and a process for the preparation thereof
专利号:US-6525220-B2
优先权日:1999-06-28
标 题 :Intermediates for the synthesis of benzimidazole derivatives and a process for the preparation thereof
专利号:EP-1191019-A1
优先权日:1999-06-28
标题 :Intermediates for the synthesis of benzimidazole compounds and process for the preparation thereof
专利号:US-2003008907-A1
优先权日:1999-06-28
标 题:Intermediates for the synthesis of benzimidazole derivatives and a process for the preparation thereof
专利号:EP-1607385-A1
优先权日:1999-06-28
标题:Intermediates for the synthesis of benzimidazole compounds and process for the preparation thereof
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1007/s11178-005-0043-z
摘要:Zotova NV, Kushakova PM, Kuznetsov VA, Rodin AA, Garabadzhiu AV. Specific features of nucleophilic substitution in 1-chloro-3,4-dinitrobenzene. Russian Journal of Organic Chemistry. 2004 Oct;40(10):1473–6. doi: 10.1007/s11178-005-0043-z.
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