CAS: 298-00-0; Parathion-Methyl

该化合物是对各种害虫具有高毒性,因此在农业应用中有效;对硫磷-甲基的化学结构包括一个磷酸盐组,该组负责其作为乙酰胆碱酯酶抑制剂的动作模式,导致昆虫...

结构式图片

物理性质

欧盟法规

《欧盟PIC法规》统一分类与标签压力设备指令-第1组危险流体"欧盟管控危险化学品"ECHA物质欧盟气雾剂指令-标签制度ECHA物质工作场所安全标识要求OtherC&L通报REACH预注册废弃物危险特性清单

上下游产品

CAS号100-02-7 对硝基苯酚 | CAS号2524-03-0 二甲基硫代磷酰氯 | CAS号824-78-2 4-硝基苯酚钠 | CAS号28341-54-0 4-(4-硝基苯氧基)丁酸 | CAS号124-41-4 甲醇钠 | CAS号100-02-7 对硝基苯酚 | CAS号152-20-5 O,O,S-三甲基酯硫代磷酸 | CAS号950-35-6 甲基对氧磷 | CAS号131-11-3 邻苯二甲酸二甲酯; 避蚊酯 | CAS号472-41-3 4-(2,2,4-三甲基色满-... | CAS号123-31-9 对苯二酚 | CAS号507-09-5 硫代乙酸 | CAS号16604-77-6 thiophosphoric ... | CAS号597-89-7 S-methyl-methyl... | CAS号58175-57-8 2-丙基-1-戊醇

合成工艺路线路线简述

    📜对硝基苯酚 反应生成甲基对硫磷
    参考文献:Kamtekar S. D.,Shridhara Alva K.,Marx K. A.,Kumar J.,Samuelson L. A.,+,Pittsburgh Conf. [anal. Chem. And Appl. Spectrosc.] Presents Pittcon95,N+
    标题:Kamtekar S. D.,Shridhara Alva K.,Marx K. A.,Kumar J.,Samuelson L. A.,+,Pittsburgh Conf. [anal. Chem. And Appl. Spectrosc.] Presents Pittcon95,N+

    海关参考信息

    专利信息


    专利号:US-6521664-B1
    优先权日:1999-12-08
    标 题:Pesticidal activity of functionalized alkenes
    发明人:LINDERMAN RUSSELL J
    权利人:UNIV NORTH CAROLINA STATE
    摘要:The present invention provides non-peptide organic compounds that have a structure analogous to or reminiscent of the TMOF structure and have pesticidal activity. Thus the present invention concerns pesticidal compounds that inhibit digestion in pests by terminating or otherwise blocking synthesis of digestive enzymes by activating a TMOF receptor (collectively referred to herein as “pesticidal compoundsâ€?). The pesticidal compounds and other compounds of the present invention are usefully employed in the control of pests, particularly insect pests such as mosquitoes, which ingest blood.

    专利号:WO-2025056767-A1
    优先权日:2023-09-15
    标题 :Process for the preparation of enantiomerically enriched aliphatic amines
    发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

    专利号:US-2016073631-A1
    优先权日:2013-03-04
    标 题 :Process for the preparation of dihydropyrrole derivatives
    发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
    权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
    摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

    专利号:US-9233920-B2
    优先权日:2010-06-11
    标题 :Process for the preparation of dihydropyrrole derivatives
    发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
    权利人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS; SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
    摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) wherein P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; R 1 is chlorodifluoromethyl or trifluoromethyl; R 2 is optionally substituted aryl or optionally substituted heteroaryl; n is 0 or 1; including the process comprising (a-i) reacting a compound of formula II wherein P, R 1 and R 2 are as defined for the compound of formula I; with nitromethane in the presence a chiral catalyst to give a compound of formula III Wherein P, R 1 and R 2 are as defined for the compound of formula I; and (a-ii) reductively cyclizing the compound of formula III to give the compound of formula I. The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

    专利号:US-6660770-B2
    优先权日:1999-12-08
    标题:Pesticidal activity of functionalized alkenes
    发明人:LINDERMAN RUSSELL J; ROE R MICHAEL; THOMPSON DEBORAH M; VANDERHEREHEN MATTHEW
    权利人:UNIV NORTH CAROLINA STATE
    摘要:The present invention provides non-peptide organic compounds that have a structure analogous to or reminiscent of the TMOF structure and have pesticidal activity. Thus the present invention concerns pesticidal compounds that inhibit digestion in pests by terminating or otherwise blocking synthesis of digestive enzymes by activating a TMOF receptor (collectively referred to herein as “pesticidal compoundsâ€?). The pesticidal compounds and other compounds of the present invention are usefully employed in the control of pests, particularly insect pests such as mosquitoes, which ingest blood.

    专利号:US-2009100752-A1
    优先权日:2004-06-26
    标题:Device for converting carbonaceous matter into synthesis gas and associated methods
    发明人:SESSA JOHN P; CZERNICHOWSKI ALBIN; CZERNICHOWSKI MIECZYSLAW; CZERNICHOWSKI CAROLINE
    权利人:SESSA JOHN P; CZERNICHOWSKI ALBIN; CZERNICHOWSKI MIECZYSLAW; CZERNICHOWSKI CAROLINE
    摘要:A device for converting carbonaceous matter into synthesis gas includes a plasma head and a reformer connected to and extending downwardly from the plasma head. The plasma head may include a vortex zone, a plasma zone positioned beneath the vortex zone, and an oxidant input adjacent an upper portion of the vortex zone for inputting oxidant into the vortex zone. The plasma head may also include a high voltage electrode positioned to extend through a medial portion of the vortex zone and having a termination in the vortex zone so that high voltage discharge strikes are emitted into a lower portion of the vortex zone, a carbonaceous matter input for inputting carbonaceous matter into the plasma zone, and a plasma zone exit. The reformer may include a post plasma zone positioned beneath the plasma zone, a thermal barrier protective layer adjacent an uppermost portion of the post plasma zone adjacent an exit of the plasma zone, a catalyst carried by the post plasma zone, and a synthesis gas output.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Xu F, Li Y, Fu Y, Chen X, Fan S, Cao Z. A Dual-Focus Workflow for Simultaneously Engineering High Activity and Thermal Stability in Methyl Parathion Hydrolase. Angew Chem Int Ed Engl. 2024 Aug
    10:e202410881. doi: 10.1002/anie.202410881. Epub ahead of print. 460(Pt 1):140432. doi: 10.1016/j.foodchem.2024.140432. Epub ahead of print. 276(Pt 2):133979. doi: 10.1016/j.ijbiomac.2024.133979. Epub ahead of print. 10(12):e32954. doi: 10.1016/j.heliyon.2024.e32954.
    5: Shao C, Ma R, Yan Z, Li C, Hong Y, Li Y, Chen Y. Basic research for identification and classification of organophosphorus pesticides in water based on ultraviolet-visible spectroscopy information. Environ Sci Pollut Res Int. 2024 Jul;31(33):45761-45775. doi: 10.1007/s11356-024-34182-0. Epub 2024 Jul 8.

    合成参考文献


    参考文献:10.1007/s00253-010-2457-y
    摘要:Liu Y, Wei Q, Wang SJ, Liu H, Zhou NY. Construction of an engineered strain free of antibiotic resistance gene markers for simultaneous mineralization of methyl parathion and ortho-nitrophenol. Appl Microbiol Biotechnol. 2010 Jun;87(1):281–7. doi: 10.1007/s00253-010-2457-y.
    参考文献:10.1002/pmic.201100084
    摘要:Huang QY, Huang HQ. Differential expression profile of membrane proteins in zebrafish (Danio rerio) brain exposed to methyl parathion. Proteomics. 2011 Sep;11(18):3743–56. doi: 10.1002/pmic.201100084.
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