Bis(N-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinolinyl)Methane置于盐酸体系中,用 水,异丙醇 用作溶剂,化学反应 18.0H,反应生成6,7-二甲氧基-1,2,3,4-四氢异喹啉盐酸盐 参考文献:Process For The Preparation Of Substituted-1,2,3,4-Tetrahydroisoquinoline Derivatives 标题:Process For The Preparation Of Substituted-1,2,3,4-Tetrahydroisoquinoline Derivatives 摘要:本发明涉及一种用于合成替代-1,2,3,4-四氢异喹啉衍生物的过程,该衍生物可作为合成药物制剂中间体.
专利号:US-6248891-B1 优先权日:1997-05-23 标题:Synthesis of acridine derivative multidrug-resistant inhibitors 发明人:SHARP MATTHEW JUDE; MADER CATHERINE J; STRACHAN CALUM 权利人:GLAXO WELLCOME INC 摘要:Synthesis of the MDRI of formula (I) from intermediates of acridone acid of formula (II) and aminophenethyl isoquinoline of formula (III), via steps including coupling and conversion to yield the MDRI of formula (I).
专利号:US-7872138-B2 优先权日:2006-08-07 标 题 :Process for the preparation of substituted-1,2,3,4-tetrahydroisoquinoline derivatives 发明人:VILLANI FRANK J; ZHONG HUA 权利人:JANSSEN PHARMACEUTICA NV 摘要:The present invention is directed to a process for the synthesis of substituted-1,2,3,4-tetrahydroisoquinoline derivatives, useful as intermediates in the synthesis of pharmaceutical agents.
专利号:US-5663449-A 优先权日:1989-05-19 标 题 :Intermediate compounds in the synthesis of heteroarylpiperidines, pyrrolidines and piperazines
专利号:WO-9852923-A1 优先权日:1997-05-23 标题:Synthesis of acridine derivative multidrug-resistant inhibitors
专利号:EP-0983246-B1 优先权日:1997-05-23 标 题:Synthesis of acridine derivative multidrug-resistant inhibitors
专利号:US-11999754-B2 优先权日:2018-04-16 标题:Ruthenium complexes and their use in olefin metathesis reactions 发明人:GAWIN RAFAL; KRAJCZY PATRYK; GAWIN ANNA; SKOWERSKI KRZYSZTOF 权利人:APEIRON SYNTHESIS SA 摘要:The invention relates to a ruthenium complex of formula (1), (1) wherein all variables have a meaning as defined in the specification to be used as a (pre)catalyst in the olefin metathesis reaction, ring metathesis reaction (RCM), homometathesis (self-CM), cross-metathesis including ethanolysis (CM).