CAS: 18524-67-9; Mycobacillin

该化合物是一种自然形成的抗生素,属于被称为巴氏素的化合物类别,这些化合物是由某些亚丁酸菌菌株产生的,主要以其对抗各种抗原细菌的效力而著称,特别是抗菌菌菌中的抗菌菌,特别是抗菌菌菌中的抗菌菌,而这种抗生素则呈现出一种复杂的结构,其特征是环状脊柱,有助于其抗菌活动.通过抑制细菌细胞壁合成,从而阻止易感染细菌的生长和复制,这种复合功能的复合功能常常被研究其潜在的治疗用途,特别是治疗抗菌菌株感染的潜在治疗用途.此外,对它的临床用途进行了调查,但由于潜在的毒性和更有效的抗生素供应,因此它的临床用途受到限制.同许多抗生素一样,抗体的出现对其功效构成挑战,需要不断研究其机制以及现代医学的潜在应用.

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MSDS等安全信息

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      专利信息


      专利号:US-5662898-A
      优先权日:1990-08-20
      标 题 :Genes for the synthesis of antipathogenic substances
      发明人:LIGON JAMES M; HILL DWIGHT STEVEN; LAM STEPHEN TING; HAMMER PHILIP E
      权利人:CIBA GEIGY CORP
      摘要:The present invention is directed to the production of an antipathogenic substance (APS) in a host via recombinant expression of the polypeptides needed to biologically synthesize the APS. Genes encoding polypeptides necessary to produce particular antipathogenic substances are provided, along with methods for identifying and isolating genes needed to recombinantly biosynthesize any desired APS. The cloned genes may be transformed and expressed in a desired host organisms to produce the APS according to the invention for a variety of purposes, including protecting the host from a pathogen, developing the host as a biocontrol agent, and producing large, uniform amounts of the APS.

      专利号:US-5817502-A
      优先权日:1994-06-08
      标题 :Genes for the synthesis of pyrrolnitrin

      专利号:US-5639949-A
      优先权日:1990-08-20
      标 题 :Genes for the synthesis of antipathogenic substances

      专利号:WO-9533818-A2
      优先权日:1994-06-08
      标 题:Genes for the synthesis of antipathogenic substances

      专利号:US-5698425-A
      优先权日:1990-08-20
      标 题:Method of protecting plants by transformation with genes for the synthesis of antipathogenic substances

      专利号:SK-156996-A3
      优先权日:1994-06-08
      标 题 :A molecule of isolated dna for the synthesis of antipathogenic substances, vectors and hosts comprising this molecule and its use

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      ✅ COA系统入驻 | 共享模式

      合成参考文献


      参考文献:10.1099/00221287-131-10-2783
      摘要:Majumdar S, Bose SK. Derepression of sporulation and synthesis of mycobacillin and dipicolinic acid by guanosine 3':5'-cyclic monophosphate under conditions of glucose repression in Bacillus subtilis. J Gen Microbiol. 1985 Oct;131(10):2783–8. doi: 10.1099/00221287-131-10-2783.
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