专利号:US-5662898-A 优先权日:1990-08-20 标 题 :Genes for the synthesis of antipathogenic substances 发明人:LIGON JAMES M; HILL DWIGHT STEVEN; LAM STEPHEN TING; HAMMER PHILIP E 权利人:CIBA GEIGY CORP 摘要:The present invention is directed to the production of an antipathogenic substance (APS) in a host via recombinant expression of the polypeptides needed to biologically synthesize the APS. Genes encoding polypeptides necessary to produce particular antipathogenic substances are provided, along with methods for identifying and isolating genes needed to recombinantly biosynthesize any desired APS. The cloned genes may be transformed and expressed in a desired host organisms to produce the APS according to the invention for a variety of purposes, including protecting the host from a pathogen, developing the host as a biocontrol agent, and producing large, uniform amounts of the APS.
专利号:US-5817502-A 优先权日:1994-06-08 标题 :Genes for the synthesis of pyrrolnitrin
专利号:US-5639949-A 优先权日:1990-08-20 标 题 :Genes for the synthesis of antipathogenic substances
专利号:WO-9533818-A2 优先权日:1994-06-08 标 题:Genes for the synthesis of antipathogenic substances
专利号:US-5698425-A 优先权日:1990-08-20 标 题:Method of protecting plants by transformation with genes for the synthesis of antipathogenic substances
专利号:SK-156996-A3 优先权日:1994-06-08 标 题 :A molecule of isolated dna for the synthesis of antipathogenic substances, vectors and hosts comprising this molecule and its use
参考文献:10.1099/00221287-131-10-2783 摘要:Majumdar S, Bose SK. Derepression of sporulation and synthesis of mycobacillin and dipicolinic acid by guanosine 3':5'-cyclic monophosphate under conditions of glucose repression in Bacillus subtilis. J Gen Microbiol. 1985 Oct;131(10):2783–8. doi: 10.1099/00221287-131-10-2783.