专利号:US-2006234990-A1 优先权日:1999-04-30 标题 :Compositions of boswellic acids derived from Boswellia serrata gum resin, for treating lymphoproliferative and autoimmune conditions 发明人:MAJEED MUHAMMED; BADMAEV VLADIMIR 权利人:SAMI LABS LTD 摘要:A method of treatment of lymphoproliferative and autoimmune disorders with a new composition of four boswellic acids including β-boswellic acid, 3-O-acetyl-β-boswellic acid, 11-keto-β-boswellic acid, and 3-O-acetyl-11-keto-β-boswellic acid. Boswellic acids of invention have been obtained in a novel industrial process from the gum resin of Boswellia serrata tree, providing standardized composition which inhibits DNA, RNA and protein synthesis of the target cell without cytotoxic effects. The composition of invention provides advantage of irreversible cytostatic therapy, equivalent to biological effects of a cytotoxic therapy without killing body cells.
专利号:WO-2008058514-A1 优先权日:2006-11-14 标 题:Preparations comprising boswellic acids for inhibiting the synthesis of prostaglandin e2 发明人:WERZ OLIVER; SIEMONEIT ULF 权利人:UNIV EBERHARD KARLS; WERZ OLIVER; SIEMONEIT ULF 摘要:The present invention relates to the use of preparations with pentacyclic triterpenoic acids and structural derivatives thereof, in particular boswellic acids from Boswellia species (such as B. serrata, B. carterii, B. sacra), for inhibiting the inducible mitochondrial prostaglandin E2 synthase-1. In addition, the invention relates to the use of pentacyclic triterpenoic acids and derivatives thereof for producing a medicament for the treatment of PGE2-mediated diseases.
专利号:WO-02085921-A2 优先权日:2001-03-01 标 题 :Simple method for the synthesis of boswellic acids and derivatives thereof
专利号:DE-102006053475-A1 优先权日:2006-11-14 标题:Preparations for the inhibition of prostaglandin E2 synthesis