CAS: 16720-80-2; Dl-Methioninol

该化合物是在蛋白合成过程中,并作为其他含硫化合物的前体.其抗氧化特性既涉及食品化学,也涉及药品,因为它可能有助于防止细胞受到氧化性压力.此外,该化合物由于芳香味,在香味工业中被使用.安全数据表明,尽管一般认为该物质在适当的浓度中是安全的,但在处理时应当小心避免潜在的刺激或不利反应.

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上下游产品

D-methionine isopropyl ester tert-butyl (1R)-1-(hydroxymethyl)-3-(methylsulfanyl)propylcarbamate D-methionine N-t-butoxycarbonyl-D-methionineR)-4-methylsulfanyl-2-(4-nitro-benzoylamino)-1-(4-nitro-benzoyloxy)-butane(R)-4-methylsulfanyl-2-(4-nitro-benzoylamino)-1-(4-nitro-benzoyloxy)-butane 3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-4-methylsulfanyl-2-(3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-butyl ester -2-phenyl-1,3-oxazole(4S)-4,5-dihydro-4-2-(methylsulfanyl)ethyl-2-phenyl-1,3-oxazole (R)-N-[1-hydroxy-4-(methylthio)butan-2-yl]-4-methylbenzenesulfonamide

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    专利信息


    专利号:US-10040752-B2
    优先权日:2015-08-24
    标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof
    发明人:MKRTCHYAN GNEL; YAO QINGWEI
    权利人:CODY LABORATORIES INC
    摘要:Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

    专利号:US-9206222-B2
    优先权日:2009-06-29
    标题:Solid phase peptide synthesis of peptide alcohols
    发明人:CAUSSIL-AMBLARD MURIEL; MARTINEZ JEAN; TAILHADES JULIEN
    权利人:CAUSSIL-AMBLARD MURIEL; MARTINEZ JEAN; TAILHADES JULIEN; CENTRE NAT RECH SCIENT
    摘要:The present invention relates to the synthesis of depsipeptides on solid phase support. Said depsipeptides are then implicated in a solution phase O—N acyl shift enabling to obtain the corresponding peptide alcohols.

    专利号:US-2021171437-A1
    优先权日:2017-07-17
    标题 :Peptide nucleic acid (pna) monomers with an orthogonally protected ester moiety and novel intermediates and methods related thereto
    发明人:COULL JAMES M; GILDEA BRIAN D
    权利人:VERA THERAPEUTICS INC
    摘要:The present disclosure pertains to peptide nucleic acid (PNA) monomers and oligomers, as well as methods and compositions useful for the preparation of PNA monomer precursors (e.g. PNA Monomer Esters, Backbone Esters and Backbone Ester Acid Salts, as described below) that can be used to prepare PNA monomers wherein said PNA monomers can be used to prepare said PNA oligomers. In some embodiments, the disclosure features sulfonic acid salts of Backbone Ester compounds, which sulfonic acid salts generally tend to be crystalline and can be obtained in reasonably good yield, often without requiring any chromatographic purification of the reaction product of the Backbone Ester synthesis reaction. This disclosure also pertains to novel methods for the synthesis of said Backbone Ester compounds and novel methods for the formation of the related sulfonic acid salts. Exemplary ester groups include, but are not limited to, 2,2,2-trichloroethy-(TCE), 2,2,2-tribromoethyl-(TBE), 2-iodoethyl-groups (2-IE) and 2-bromoethyl-(2-BrE) as the ester group. These particular ester groups can be removed under conditions where both Boc and Fmoc protected amine groups are stable.

    专利号:US-2019002394-A1
    优先权日:2015-08-24
    标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof

    专利号:US-2012108748-A1
    优先权日:2009-06-29
    标 题:Solid phase peptide synthesis of peptide alcohols

    专利号:EP-2448956-B1
    优先权日:2009-06-29
    标题:Solid phase peptide synthesis of peptide alcohols

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    合成参考文献


    参考文献:10.1055/s-2008-1078572
    摘要:Lin X, Chen W, Zhang Q, Liu B, Wu Q. A Catalyst-Free, Convenient Construction of Eight-Membered [1,4]Oxazocane-5,8-dione Heterocycles from Aminoethanols with Divinyl Succinate. Synlett. 2008 Jul 02;2008(12):1829–32. doi: 10.1055/s-2008-1078572.
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