CAS: 1571-30-8; 8-Hydroxyquinoline-2-Carboxylic Acid

相似化合物

14510-06-6 6759-78-0 59-00-7

上下游产品

8-methoxyquinoline-2-carboxylic acid 4-Chlor-8-hydroxychinaldinsaeure 5-bromo-8-methoxy-quinoline-2-carboxylic acid 8-hydroxyquinoline-2-carbonitrile methyl 8-hydroxyquinoline-2-carboxylate 8-hydroxyquinoline-2-carboxylic acid chloride rac-2-(benzyloxycarbonyl-amino)-3-[(8-trifluoromethanesulfonyloxy-quinoline-2-carbonyl)amino]propionic acid methyl ester 8-hydroxy-quinoline-2-carboxylic acid benzyl ester

📜8-羟基喹啉-2-甲腈置于水,Sodium Hydroxide体系中,化学反应 6.0H,以100%的收率获得8-羟基喹啉-2-羧酸
参考文献:高价碘(III)介导的喹啉n-氧化物与三甲基甲硅烷基氰化物的区域选择性氰化
标题:高价碘(III)介导的喹啉n-氧化物与三甲基甲硅烷基氰化物的区域选择性氰化
摘要:在无金属和无碱反应条件下,使用(二乙酰氧基碘)苯(pida)作为介导的高价碘(III)试剂,开发了用三甲基甲硅烷基氰化喹啉n-氧化物的区域选择性氰化反应,从而获得2-氰基喹啉.高效的pida试剂可以起到底物的活化剂和n-O键断裂促进剂的作用.该反应系统具有广泛的底物适用性和高收率的特点.该程序以克级放大以合成结核病(tb)抑制剂.最后,根据一些实验结果,提出了合理的氰化反应机理.
Doi:10.1002/adsc.201801185

专利信息

专利号:US-5502126-A
优先权日:1993-06-17
标 题 :Process for the synthesis of isoprene butadiene rubber
发明人：BELL ANTHONY J; MATRANA BARRY A; HALASA ADEL F
权利人:GOODYEAR TIRE & RUBBER
摘要:The subject invention relates to a technique for synthesizing rubbery non-tapered, random, copolymers of 1,3-butadiene and isoprene. These rubbery copolymers exhibit an excellent combination of properties for utilization in tire sidewall rubber compounds for truck tires. By utilizing these isoprene-butadiene rubbers in tire sidewalls, tires having improved cut growth resistance can be built without sacrificing rolling resistance. Such rubbers can also be employed in tire tread compounds to improve tread wear characteristics and decrease rolling resistance without sacrificing traction characteristics. This invention more specifically discloses a process for the synthesis of isoprene-butadiene rubbers which comprises copolymerizing isoprene monomer and 1,3-butadiene monomer in an organic solvent in the presence of a catalyst system which is made by the sequential steps of (1) mixing (a) an organoaluminum hydride, (b) a member selected from the group consisting of aliphatic alcohols, cycloaliphatic alcohols, aliphatic thiols, cycloaliphatic thiols, trialkyl silanols, and triaryl silanols, and (c) optionally, 1,3-butadiene in an organic solvent to produce a modified organoaluminum catalyst component; (2) adding an organometallic compound which contains a metal from Group III-B of the Periodic System to the modified organoaluminum catalyst component to produce a Group III-B metal containing catalyst component; and (3) adding a compound which contains at least one labile halogen atom to the Group III-B metal containing catalyst component.

专利号:US-9574189-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries
发明人：FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

专利号:US-7968752-B2
优先权日:2003-06-16
标 题:Hydrolytically-resistant boron-containing therapeutics and methods of use
发明人：LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
权利人:ANACOR PHARMACEUTICALS INC
摘要:Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

专利号:US-8987451-B2
优先权日:2012-01-03
标题 :Synthesis of cyclometallated platinum(II) complexes
发明人：TSAI JUI-YI; KOTTAS GREGG; YEAGER WALTER
权利人:UNIVERSAL DISPLAY CORP
摘要:A single-step method of making tetradentate platinum complexes is disclosed. The method advantageously allows the formation of a platinum complex in a single step, even with sterically hindered ligands, without the use of highly reactive intermediates. The compounds made by the disclosed method are useful in OLED applications.

专利号:US-2003125487-A1
优先权日:2001-12-31
标题 :Group III-B metal catalyst system
发明人：HSU WEN-LIANG; HALASA ADEL FARHAN; JASIUNAS CHAD AARON
权利人:HSU WEN-LIANG; HALASA ADEL FARHAN; JASIUNAS CHAD AARON
摘要:The subject invention relates to a technique for synthesizing rubbery non-tapered, random, copolymers of 1,3-butadiene and isoprene. These rubbery copolymers exhibit an excellent combination of properties for utilization in tire sidewall rubber compounds for truck tires. By utilizing these isoprene-butadiene rubbers in tire sidewalls, tires having improved cut growth resistance can be built without sacrificing rolling resistance. Such rubbers can also be employed in tire tread compounds to improve tread wear characteristics and decrease rolling resistance without sacrificing traction characteristics. This invention more specifically discloses a process for the synthesis of isoprene-butadiene rubbers which comprises copolymerizing isoprene monomer and 1,3-butadiene monomer in an organic solvent in the presence of a catalyst system that is comprised of (I) a compound which contains at least one labile halogen atom and (II) a Group III-B metal containing catalyst component which is made by the sequential steps of (1) mixing (a) an organoaluminum hydride, (b) a member selected from the group consisting of aliphatic alcohols, cycloaliphatic alcohols, aliphatic thiols, cycloaliphatic thiols, trialkyl silanols, and triaryl silanols, and (c) optionally, 1,3-butadiene in an organic solvent to produce a modified organoaluminum catalyst component, and (2) adding an organometallic compound which contains a metal from Group III-B of the Periodic System to the modified organoaluminum catalyst component to produce a Group III-B metal containing catalyst component.

专利号:US-2024010585-A1
优先权日:2020-11-27
标 题 :Reduction by a silane in the presence of zinc catalyst
发明人：JERPHAGNON THOMAS; PASTORI JOEL
权利人:FIRMENICH & CIE
摘要:The present invention relates to the field of organic synthesis. More specifically, it concerns a process for the selective reduction of a C 3 -C 70 substrate containing one or more carbonyl or carboxylic functional groups into the corresponding 5 alcohol diol, or polyalcohol in the presence of a silane and at least one catalyst or pre-catalyst in the form of a zinc complex. The Zinc complex of formula (I) or (II) is also part of the invention.