CAS: 14352-61-5; Methyl Cyclohexylacetate

该化合物是一种循环酯化合物,其特点是在有机合成和工业工艺中具有多种用途,其结构将环氧环乙烷主干和乙酸酯功能组结合在一起,在一系列反应条件下具有有利的溶性性和稳定性,该化合物因其能经受洗涤,氢化和其他转化,在香气,药品和特殊化学品生产过程中特别被视为中间体,其挥发性相对较低,与普通有机溶剂的兼容性增强了其在配方中的效用.

结构式图片

相似化合物

5292-21-7 4442-79-9 5664-21-1

欧盟法规

REACH注册ECHA物质C&L通报

上下游产品

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合成工艺路线路线简述

    📜苯乙酸甲酯置于c33H49Clnrh,氢气体系中,用 2,2,2-三氟乙醇 用作溶剂,20.0 °C,1.0 Mpa 条件下,反应 24.0H,以83%的收率获得环己基乙酸甲酯
    参考文献:环状(氨基)(烷基)卡宾铑配合物实现芳香酮和酚的高选择性氢化
    标题:环状(氨基)(烷基)卡宾铑配合物实现芳香酮和酚的高选择性氢化
    摘要:由强 σ 供体环状(氨基)(烷基)卡宾 (Caac) 连接的空气稳定的 Rh 配合物通过还原芳基显示出独特的催化活性,可用于芳香酮和苯酚的选择性氢化.Caac 配体的使用对于实现高选择性和转化率至关重要.该方法的特点是与不饱和酮,酯,羧酸,酰胺和氨基酸具有非常好的相容性,并且可以在不影响其效率的情况下进行扩展.
    Doi:10.1021/jacs.5B05868

    海关参考信息

    专利信息


    专利号:US-3887490-A
    优先权日:1970-08-27
    标 题 :Process for regenerating noble metal catalyst for the synthesis of hydrogen peroxide according to the anthraquinone process
    发明人:SCHREYER GERD; THEISSEN FERDINAND; WEIBERG OTTO; WEIGERT WOLFGANG
    权利人:DEGUSSA
    摘要:In situ regeneration of noble metal catalysts for the synthesis of hydrogen peroxide by the anthraquinone process is provided by employing as the working solution coming from the extraction or desorption step and being introduced into the hydrogenation step a solution which contains at least 250 mg/liter of hydrogen peroxide, to thereby completely regenerate the noble metal catalyst by full capacity of the hydrogenation step.

    专利号:EP-2097079-B1
    优先权日:2006-11-30
    标题:Modulation of prostaglandin/cyclooxygenase metabolic pathways
    发明人:WUELFERT ERNST
    权利人:HUNTER FLEMING LTD
    摘要:A variety of diseases and disorders associated with the metabolic pathways involved in the activities of cyclooxygenase and the synthesis of prostaglandins, for example type 2 diabetes mellitus and its sequelae, ischemic vascular diseases, pain associated with inflammation, inflammatory skin conditions, spinal cord injury, peripheral neuropathy, multiple sclerosis, inflammatory bowel disease and rheumatoid arthritis, as well as various types of cancer may be treated or prevented by the use of an agent which selectively enhances production of 15-deoxy-prostaglandin J2. The compounds are 7-hydroxy-steroids or condensed indoles.

    专利号:WO-2013066991-A1
    优先权日:2011-10-31
    标题 :Crystalline solvates of nucleoside phosphoroamidates, their stereoselective preparation, novel intermediates thereof, and their use in the treatment of viral disease
    发明人:CHAMBERLAIN STANLEY; IGO DAVID; BIS JOANNA; SUKUMAR SENTHIL KUMAR KUSALAKUMARI
    权利人:INHIBITEX INC
    摘要:This invention is directed to novel crystalline solvates of the ( S )-P diastereomer of the anti- HCV nucleoside phosphoroamidate, (2 S )-neopentyl 2-((((2 R ,3 R ,4 R ,5 R )-5-(2-amino-6- methoxy-9H-purin-9-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(naphthalen- l-yloxy)phosphorylamino)propanoate (also referred to as INX-08189 or IÎ?Χ-189), and to a recrystallization method for separating the two diastereomers of INX-08189. In addition, this application relates to a novel stereoselective method for the preparation of either of the two diastereomers, and to the novel synthetic intermediates used in this stereoselective synthesis. The invention also relates to the use of the crystalline solvates to increase the liver exposure of 2'-C-methyl guanosine triphosphate from an oral dose.

    专利号:US-5827855-A
    优先权日:1992-12-28
    标题 :Hexahydronaphthalene ester derivatives their preparation and their therapeutic uses
    发明人:KOGEN HIROSHI; ISHIHARA SADAO; KOGA TEIICHIRO; KITAZAWA EIICHI; SERIZAWA NOBUFUSA; HAMANO KIYOSHI
    权利人:SANKYO CO
    摘要:Compounds of formula (I): (I) wherein R1 represents a group of formula (II) or (III): (II) (III) R2 is alkyl, alkenyl or alkynyl; R3 and R4 are each hydrogen, alkyl, alkenyl or alkynyl; R5 is hydrogen or a carboxy-protecting group; Ra is a group of formula -OR6; R6 is hydrogen; R6a and R6b are each hydrogen, a hydroxy-protecting group, alkyl, alkanesulfonyl, halogenated alkanesulfonyl or arysulfonyl, and their salts and esters. Such compounds inhibit the synthesis of cholesterol, and can be used for the treatment and prophylaxis of hypercholesterolemia and of various cardiac disorders.

    专利号:RU-2139283-C1
    优先权日:1994-12-15
    标题:Derivative of thiazolidinone showing collateral-dilatating activity of vessel, pharmaceutical composition containing on said for treatment and prophylaxis of stenocardia and method of synthesis of indicated thiazolidinone derivatives

    专利号:US-5491167-A
    优先权日:1993-01-29
    标题 :Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses
    发明人:ISHIHARA SADAO; KOGEN HIROSHI; KOGA TEIICHIRO; KITAZAWA EIICHI; SERIZAWA NOBUFUSA
    权利人:SANKYO CO
    摘要:Compounds of formula (I): ##STR1## and their salts and esters have the ability to inhibit the synthesis of cholesterol, and can thus be used for the treatment and prophylaxis of hypercholesterolemia and of various cardiac disorders.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Marsden, S. P., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 586.
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