CAS: 1170-76-9; (S)-2-(2-(((Benzyloxy)Carbonyl)Amino)Acetamido)-3-Phenylpropanoic Acid

该化合物是一种合成化合物,属于氨基酸和酸类,该物质具有一种苯基组,有助于其芳香特性,一种液态混合物,表明其结构包括一种甘油衍生物.苯氧基碳基化合物组的存在表明它具有保护性或修改性功能,经常用于浸渍合成,以提高稳定性或溶性.L-aline成分表明它是一种光学活性氨酸,可影响其生物活动和相互作用.该化合物可能表现出聚醚的典型特性,例如潜在的生物活性,极地溶剂溶解性以及因其功能组而形成氢结的能力.其具体应用可能不同,但可能与药物研究有关,特别是在开发基于浸底药物或作为有机合成的建筑块.

结构式图片

物理性质

MSDS等安全信息

上下游产品

CAS号2899-60-7 Z-甘氨酸 N-琥珀酰亚胺酯 | CAS号63-91-2 L-苯丙氨酸 | CAS号1138-80-3 N-苄氧羰基甘氨酸 | CAS号1161-13-3 N-苄氧羰基-L-苯丙氨酸 | CAS号16881-34-8 Z-L-Phe-O(t-Bu) | CAS号150-30-1 DL-苯丙氨酸 | CAS号543-27-1 氯甲酸异丁酯 | CAS号17942-42-6 L-Phenylalanine... | CAS号2387-23-7 N,N’-二环己基脲 | CAS号317383-50-9 N-benzyloxycarb... | CAS号3321-03-7 甘氨酰苯基丙氨酸 | CAS号3480-80-6 Z-Gly-Phe-Ala-OH | CAS号6206-42-4 L-Phenylalanine...

合成工艺路线路线简述

    📜N-苄氧羰基-L-苯丙氨酸置于palladium On Activated Charcoal 四乙基焦亚磷酸盐,硫酸,氢气,对甲苯磺酸体系中,用 乙醇,二氯甲烷,N,N-二甲基甲酰胺,苯 用作溶剂,化学反应生成N-苄氧羰基甘氨酰-L-苯丙氨酸
    参考文献:T-Butyl Esters Of Amino Acids And Peptides And Their Use In Peptide Synthesis1
    标题:T-Butyl Esters Of Amino Acids And Peptides And Their Use In Peptide Synthesis1
    摘要:
    Doi:10.1021/ja01498A032

    海关参考信息

    专利信息


    专利号:US-2019276389-A1
    优先权日:2015-12-18
    标题:Synthesis of aryl cyclohexane ester derivatives useful as sensates in consumer products
    发明人：WOS JOHN AUGUST; YELM KENNETH EDWARD; BUNKE GREGORY MARK; FREDERICK HEATH ALAN; REILLY MICHAEL; HAUGHT JOHN CHRISTIAN; SREEKRISHNA KOTI TATACHAR; LIN YAKANG
    权利人:PROCTER & GAMBLE
    摘要:Personal care compositions, such as oral care and skin care compositions containing a flavor/perfume system comprising one or more coolants. The pleasant cool sensation provided by a coolant is enhanced in terms of quicker onset, greater intensity, impact or longer duration, which improves appeal and acceptability of the compositions to consumers.

    专利号:WO-2013135786-A1
    优先权日:2012-03-14
    标题 :Enzymatic peptide synthesis
    发明人：QUAEDFLIEG PETER JAN LEONARD MARIO; NUIJENS TIMO; STROHMEIER GERNOT; BREINBAUER ROLF; SCHROEDER HILMAR
    权利人:DSM FINE CHEM AUSTRIA GMBH
    摘要:According to the present invention it is shown that under appropriate conditions the catalyzed addition of alkynes is a convenient method for the racemisation-free preparation of C-terminal oligopeptide enol esters, which can be used as substrates for the enzymatic peptide coupling using a serine endopeptidase.

    专利号:EP-3390352-A1
    优先权日:2015-12-18
    标题:Synthesis of cyclohexane ester derivatives useful as sensates in consumer products

    专利号:WO-2017106279-A1
    优先权日:2015-12-18
    标 题 :Synthesis of cyclohexane ester derivatives useful as sensates in consumer products

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    主要参考文献

    参考标题:Carboxylic Acids As A Traceless Activation Group For Conjugate Additions: A Three-Step Synthesis Of (+/-)-Pregabalin
    作者:Lingling Chu,Chisa Ohta,Zhiwei Zuo,David W. C. Macmillan |发布日期:2014.8.6
    摘要:Carboxylic Acids As A Traceless Activation Group For Radical Michael Additions Has Been Accomplished Via Visible Light-Mediated Photoredox Catalysis. Photon-Induced Oxidation Of A Broad Series Of Carboxylic Acids, Including Hydrocarbon-Substituted, α-Oxy, And α-Amino Acids, Provides A Versatile Co2-Extrusion Platform To Generate Michael Donors Without The Requirement For Organometallic Activation Or Propagation

    合成参考文献


    参考文献:10.1016/0005-2736(92)90076-x
    摘要:Booz GW, Bianchi CP. Stimulation-enhanced 3-O-methylglucose efflux from the frog sartorius: kinetics and properties of the system. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1992 Aug 24;1109(2):132–40. doi: 10.1016/0005-2736(92)90076-x.
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