CAS: 88496-88-2; Sec-Butylboronic Acid

该化合物是一种有机有机体化合物,其特征是丁烷脊椎上有一个含有黄酸功能组,该化合物通常具有boron酸的特性,例如能够形成可逆的共价结合二醇,使其在各种应用中有用,包括有机合成和药用化学.Buntane-2-boronic酸很可能是白色的,白色的固体,溶于水和酒精等极地溶剂,在标准条件下可能具有中等稳定性.其再活性受boron atom的影响,该原子可参与核循环反应,并通过铃木的组合反应作为形成碳-碳联系的关键中间体.此外,丁烷链的存在可能会产生特定的氮和电子影响,影响其与其他化学物种的再活动与互动.

结构式图片

相似化合物

17745-45-8 80041-89-0 84110-40-7

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CAS号121-43-7 硼酸三甲酯 | CAS号671795-46-3 sec-BuMgBr | CAS号25027-33-2 1-butan-2-yl-4-... | CAS号72824-01-2 2-butan-2-yl-1,...

合成工艺路线路线简述

  • 合成目标产物 Buntane-2-Boronic Acid 主要起始原料 Trimethyl Borate And Sec-Bumgbr, Fandachem
  • 922-66-7 = 88496-88-2
    反应条件:1.1 Reagents: Trimethyl Borate Solvents: Diethyl Ether; 10 Min,-78 °C; -78 °C -> -60 °C; Overnight,-60 °C -> Rt; Rt -> 0 °C1.2 Reagents: Sulfuric Acid Solvents: Water; 0 °C; 0 °C -> Rt; 20 Min,Rt
    标题:Highly E-Selective Olefin Synthesis Catalysed By Novel Quinoxalinone Photocatalyst Under Visible Light Conditions
    作者:Xu,Xin; Et Al
    参考文献:Chemistry - A European Journal 日期:2023 卷标:29(27)]

    = 88496-88-2
    反应条件:1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Diethyl Ether; Reflux; Overnight,Reflux2.1 Reagents: Trimethyl Borate Solvents: Diethyl Ether; 10 Min,-78 °C; -78 °C -> -60 °C; Overnight,-60 °C -> Rt; Rt -> 0 °C2.2 Reagents: Sulfuric Acid Solvents: Water; 0 °C; 0 °C -> Rt; 20 Min,Rt
    标题:Highly E-Selective Olefin Synthesis Catalysed By Novel Quinoxalinone Photocatalyst Under Visible Light Conditions
    作者:Xu,Xin; Et Al
    参考文献:Chemistry - A European Journal 日期:2023 卷标:29(27)
硼酸三甲酯,Sec-Bumgbr 反应生成 仲丁基硼酸
参考文献:Organoboron Compounds. Ii. Preparation And Properties Of Some Trialkylboroxines1-3
标题:Organoboron Compounds. Ii. Preparation And Properties Of Some Trialkylboroxines1-3
摘要:
DOI:10.1021/ja01576A026

海关参考信息

专利信息


专利号:US-10844081-B2
优先权日:2015-08-07
标题 :Protected organoboronic acids with tunable reactivity, and methods of use thereof
发明人:BURKE MARTIN D; SCHMIDT MICHAEL; MOREHOUSE GREG; PIPAL ROBERT W
权利人:UNIV ILLINOIS
摘要:Disclosed are a range of protected organoboronic acid reagents useful in the modular assembly of complex organic compounds. The reactivities of the protected organoboronic acid reagents may be varied predictably by changes to the number and identities of their substituents. Also disclosed are methods of using the protected organoboronic acid reagents in the synthesis of organic compounds.

专利号:US-8207337-B2
优先权日:2007-01-29
标 题:Reagent for organic synthesis reaction containing organic triol borate salt
发明人:MIYAURA NORIO; YAMAMOTO YASUNORI
权利人:MIYAURA NORIO; YAMAMOTO YASUNORI; WAKO PURE CHEM IND LTD
摘要:[Problem] n To provide an organoboron compound-containing reagent for organic synthesis reactions which undergoes no trimerization with dehydration, does not necessitate activation with a base, and is stable and highly active. n [Means for Solving Problems] n The reagent for organic synthesis reactions contains an organic triol borate salt represented by any of the general formulae (I) to (III) and general formula (XVI): (wherein R 1 represents alkyl, alkenyl, etc.; R 2 represents optionally substituted alkyl, alkenyl, alkynyl, etc. or represents hydrogen; m + represents an alkaline metal ion, phosphonium ion, or given ammonium ion; M 2+ represents an alkaline earth metal; X represents halogen or alkoxide; Y represents an alkali metal ion, etc.; A represents optionally substituted methylene; and n represents an integer).

专利号:US-10072028-B2
优先权日:2013-11-03
标题:Cross-coupling of unactivated secondary boronic acids
发明人:BURKE MARTIN D; WANG PULIN; CROUCH IAN
权利人:UNIV ILLINOIS
摘要:Provided are methods for site- and stereo-retentive cross-couplings with unactivated secondary boronic acids, which methods are particularly useful in building block-based approach for small molecule synthesis. Also provided is a method of forming an air-stable chiral secondary boronic acid.
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合成参考文献


摘要:André-Joyaux, E.; Gnägi, L.; Meléndez, C.; Soulard, V.; Renaud, P., Science of Synthesis, (2021) , 452.
摘要:Dong, X.; Qin, H.; Chen, Y., Science of Synthesis: Hypervalent Halogens in Organic Synthesis, (2025) .
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