CAS: 78495-63-3; 2-Fluoro-6-Methoxyphenylboronic Acid

上下游产品

CAS号1256345-60-4 2-氟-6-羟基苯硼酸

(2-氟-6-甲氧基苯基)硼酸二甲酯置于盐酸体系中,化学反应生成 2-氟-6-甲氧基苯硼酸
参考文献:Substituted 3-Amino Biaryl Propionic Acids As Potent Vla-4 Antagonists
标题:Substituted 3-Amino Biaryl Propionic Acids As Potent Vla-4 Antagonists
摘要:A Series Of Substituted N-(3,5-Dichlorobenzenesulfonyl)-(L)-Prolyl-And (L)-Azetidyl-Beta-Biaryl Beta-Alanine Derivatives Was Prepared As Selective And Potent Vla-4 Antagonists. The 2,6-Dioxygenated Biaryl Substitution Pattern Is Important For Optimizing Potency. Oral Bioavailability Was Variable And May Be A Result Of Binding To Circulating Plasma Proteins. (C) 2002 Elsevier Science Ltd. All Rights Reserved.
DOI:10.1016/s0960-894X(02)00460-2

专利信息

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优先权日:2018-11-16
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发明人：PARSONS ANDREW THOMAS; COCHRAN BRIAN MCNEIL; POWAZINIK IV WILLIAM; CAPORINI MARC ANTHONY
权利人:AMGEN INC
摘要:The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure n nuseful for the synthesis of compounds that target KRAS G12C mutations, such as

专利号:US-2006089405-A1
优先权日:2004-10-21
标 题 :Asymmetric synthesis of dihydrobenzofuran derivatives
发明人：ZHOU DAHUI; STACK GARY P; GONTCHAROV ALEXANDER V
权利人:WYETH CORP
摘要:This invention concerns a process for the preparation of benzofuran derivatives. In some aspects, these compounds are of formula I: n n nwherein each of R 1 , R 2 , R 3 , and R 4 is as defined herein.

专利号:US-2023192681-A1
优先权日:2019-11-14
标 题 :Improved synthesis of kras g12c inhibitor compound

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优先权日:2018-11-16
标 题:Improved synthesis of key intermediate of kras g12c inhibitor compound

专利号:US-11299491-B2
优先权日:2018-11-16
标 题:Synthesis of key intermediate of KRAS G12C inhibitor compound

专利号:US-2025206735-A1
优先权日:2018-11-16
标题:Synthesis of key intermediate of kras g12c inhibitor compound