专利号:US-2012077953-A1 优先权日:2010-09-27 标 题:Synthesis of tri-component resins
专利号:US-6995142-B2 优先权日:1998-04-30 标题 :Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis 发明人:DRAGOVICH PETER SCOTT; WEBBER STEPHEN EVAN; PRINS THOMAS JAY; ZHOU RU; MARAKOVITS JOSEPH TIMOTHY; JOHNSON JR THEODORE O 权利人:AGOURON PHARMA 摘要:Peptido and peptidomimetic compounds of the formula: n nwherein the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also provided.
参考文献:10.1055/s-2008-1032186 摘要:Katritzky A, Fedoseyenko D, Mohapatra P, Steel P. Reactions of p-Benzoquinone with Sulfur Nucleophiles. Synthesis. 2008 Mar;2008(5):777–87. doi: 10.1055/s-2008-1032186.