CAS: 694-48-4; 1,3-Dimethyl-1H-Pyrazole

相似化合物

1072-91-9 694-31-5 79080-39-0

上下游产品

CAS号5436-21-5 4,4-二甲氧基-2-丁酮 | CAS号60-34-4 甲基肼 | CAS号78-94-4 丁烯酮 | CAS号1453-58-3 3-甲基吡唑 | CAS号74-88-4 碘甲烷 | CAS号2749-59-9 1,3-二甲基-5-吡唑酮 | CAS号64429-35-2 1,3-dimethyl-5-... | CAS号85290-70-6 5-chloro-N-[1,3... | CAS号27006-76-4 5-氯-1,3-二甲基-1H-... | CAS号27006-82-2 5-氯-1,3-二甲基-1H-... | CAS号52773-23-6 1,3-二甲基-4-乙酰基吡唑 | CAS号5744-56-9 1,3-二甲基-1H-吡唑-5-甲酸 | CAS号84547-85-3 4-氯-1-甲基-1H-吡唑-3-羧酸 | CAS号25016-20-0 1-甲基吡唑-3-甲酸 | CAS号84547-86-4 4-溴-1-甲基-1H-吡唑-3-羧酸 | CAS号25016-12-0 1,3-二甲基吡唑-4-甲醛 | CAS号5775-82-6 4-溴-1,3-二甲基-1H-吡唑 | CAS号76689-64-0 5-氨基-1,3-二甲基-4-硝基吡唑 | CAS号64517-88-0 1,3-二甲基-4-氨基吡唑 | CAS号6338-45-0 1,4-二甲基-1H-咪唑

5-氯-1,3-二甲基-1H-吡唑-4-甲醛置于palladium On Activated Charcoal Potassium Permanganate,氢气,Sodium Carbonate体系中,用 水 作为反应溶剂,25.0~60.0 °C,202.65 Kpa 条件下,反应 1.0H,反应生成 1,3-二甲基吡唑
参考文献:Systemic Fungicides. The Synthesis Of Certain Pyrazole Analogues Of Carboxin
标题:Systemic Fungicides. The Synthesis Of Certain Pyrazole Analogues Of Carboxin
摘要:介绍了 1,3-二甲基-N-苯基吡唑-4-甲酰胺(3)和异构体 1,5-二甲基化合物(4)的合成方法. 1,3-二甲基-N-苯基吡唑-4-甲酰胺(3)和异构体 1,5-二甲基化合物(4)的合成方法. 羧菌素的结构类似物.本文提出了证实这些化合物结构归属的证据,并介绍了一种简便的 并介绍了从一些氨基吡唑中去除氨基的简便方法. 基的简便方法.
DOI:10.1071/ch9830135

专利信息

专利号:US-9683007-B2
优先权日:2009-12-18
标 题 :Methods for the purification of deoxycholic acid
发明人：MORIARTY ROBERT M; PRASAD ACHAMPETA RATHAN; REID JOHN GREGORY; SWARINGEN JR ROY A
权利人:KYTHERA BIOPHARMACEUTICALS INC
摘要:Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxysteroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This inversion is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.

专利号:WO-2024020091-A1
优先权日:2022-07-19
标 题 :Inhibitors of short-chain dehydrogenase activity for reducing glial fibrillary acidic protein levels
发明人：MARKOWITZ SANFORD; PIEPER ANDREW
权利人:UNIV CASE WESTERN RESERVE; THE US GOV AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS
摘要:A method of decreasing blood glial fibrillary acidic protein (GFAP) levels in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor. Astroglia cells are the major and perhaps most abundant cell types in the brain. In healthy brain, astrocytes help with providing structural and network support for neurons and interface with the brain vasculature, including the blood-brain-barrier. Functionally, astrocytes are involved with providing neurotrophic factors (such as glial derived neurotrophic factor (GDNF)), and cytokine/chemokine release that influences the global and local inflammatory response environments, as well as working closely with neurons involved in the glutamate-glutamine synthesis/recycling pathway.

专利号:US-8003801-B2
优先权日:2005-11-22
标题:Chemical synthesis of a highly potent epothilone
发明人：NICOLAOU KYRIACOS C; PRATT BENJAMIN; ARSENIYADIS STELLIOS
权利人:SCRIPPS RESEARCH INST
摘要:A highly active synthetic epothilone compound whose activity exceeds that of either epothilone EpoA or EpoB when assayed as a cytotoxic agent against a cancer cell line is disclosed as is a pharmaceutical composition containing the synthetic epothilone.

专利号:US-9676783-B2
优先权日:2008-10-22
标 题:Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds
发明人：HAAS JULIA; ANDREWS STEVEN W; JIANG YUTONG; ZHANG GAN
权利人:ARRAY BIOPHARMA INC
摘要:Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.

专利号:US-2005085555-A1
优先权日:1997-08-21
标 题:Composition, synthesis and therapeutic applications of polyamines
发明人：MURPHY MICHAEL A; MALACHOWSKI MITCHELL R
摘要:This invention relates to a process of synthesis and composition of open chain (ring), closed ring, linear branched and or substituted polyamines, polyamine derived tyrosine phosphatase inhibitors and PPAR partial agonists/partial antagonists via a series of substitution reactions and optimizing the bioavailability and biological activities of the compounds. Polyamines prevent the toxicty of neutoxins and diabetogenic toxins including paraquat, methyphenyl pyridine radical, rotenone, diazoxide, streptozotocin and alloxan. These polyamines can be to treat neurological, cardiovascular, endocrine acquired and inherited mitochondrial DNA damage diseases and other disorders in mammalian subjects, and more specifically to the therapy of Parkinson's disease, Alzheimer's disease, Lou Gehrig's disease, Binswanger's disease, Olivopontine Cerebellar Degeneration, Lewy Body disease, Diabetes, Stroke, Atherosclerosis, Myocardial Ischemia, Cardiomyopathy, Nephropathy, Ischemia, Glaucoma, Presbycussis, Cancer, Osteoporosis, Rheumatoid Arthritis, Inflammatory Bowel Disease, Multiple Sclerosis and as Antidotes to Toxin Exposure.

专利号:US-12054833-B2
优先权日:2020-07-29
标 题:Catalyst for synthesizing organic carbonate and method of producing thereof, electrode for synthesizing organic carbonate, cell for synthesizing organic carbonate, method of producing organic carbonate, and synthesis system
发明人：FUJINUMA NAOHIRO
权利人:SEKISUI CHEMICAL CO LTD
摘要:An organic carbonate synthesis catalyst for electrochemically synthesizing an organic carbonate from carbon monoxide, comprises: an active particle containing a metal element; and a porous carbon supporting the active particle.