CAS: 32598-10-0; 2,3',4,4'-Tetrachloro-1,1'-Biphenyl
该化合物是一种氯化双联苯化合物,其分子式为C12H6Cl4;它属于多氯二苯(PCB)家族,其特点是其稳定的芳香结构和高热抗药性;该化合物主要用于研究和分析应用,因其持久性和生物累积性,成为环境和毒理学研究的参考标准;其明确界定的化学结构允许在复杂的基质中精确地识别和量化.该化合物在各种条件下的稳定性使它适合于在气相色谱学和质谱学分析中进行方法开发和校准.由于它潜在的环境和健康危害,适当的处理是必不可少的.
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: RKLLTEAEZIJBAU-UHFFFAOYSA-N
- 1S/C12H6Cl4/c13-8-2-3-9(11(15)6-8)7-1-4-10(14)12(16)5-7/h1-6H
- 计算化学: 氢键受体数*氢键供体数*可旋转键数1.0
物理性质
MSDS等安全信息
- GHS符号GHS07
- 警示词Warning
- 危险描述H302-H315-H319-H335
- 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
- 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
五氯联苯 2,3',4,4',5-Pentachlorobiphenyl 31508-00-62,3,3,4,4-五氯二苯酚 2,3,3',4,4'-Pentachlorobiphenyl 32598-14-4
2,3,3’,4,4’,5-六氯联苯 2,3,3',4,4',5-Hexachlorobiphenyl 38380-08-4
合成工艺路线路线简述
📜2,3,3',4,4',5-六氯联苯 反应生成2,3',4,4'-四氯联苯
参考文献:Oefjord Gro D.,Puhakka Jaakko A.,Ferguson John F.,Environ. Sci. And Technol.,28 (1994) N 13,S 2286-2294
标题:Oefjord Gro D.,Puhakka Jaakko A.,Ferguson John F.,Environ. Sci. And Technol.,28 (1994) N 13,S 2286-2294
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Synthesis Of Chlorinated Biphenyls By Suzuki Cross-Coupling Using Diamine Or Diimine-Palladium Complexes作者:Tuula Kylmälä,Noora Kuuloja,Youjun Xu,Kari Rissanen,Robert Franzén |发布日期:2008.8
摘要:And Their Reduced Diamine Counterparts 3B,3D-3G And 3I Form Complexes 4A-4I, 5B,5D-5G, And 5I With Pdcl2 In Dmf Or Methanol. Using 1 Mol-% Of The Isolated Complexes 4E And 5F Many Polychlorinated Biphenyls (Pcbs) Can Be Prepared In Moderate To Excellent Yields According To The Suzuki Crosscoupling Protocol With Contact To Air. Several 4-Acetylbiphen
合成参考文献
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
📝 需求与反馈
尽可能描述清楚需求与问题信息
