CAS: 16534-12-6; 4-Bromo-3,5-Dihydroxybenzoic Acid

相似化合物

34126-16-4 14348-38-0 56518-42-4

上下游产品

CAS号99-10-5 3,5-二羟基苯甲酸 | CAS号7732-18-5 水 | CAS号56518-42-4 4-溴-3,5-二甲氧基苯甲酸 | CAS号149-91-7 没食子酸; 3,4,5-三羟基苯甲酸 | CAS号26050-64-6 4-溴-3,5-二甲氧基苯甲酸甲酯 | CAS号31558-40-4 4-溴-3,5-二甲氧基苯甲醛 | CAS号61367-62-2 4-溴-3,5-二甲氧基苯甲醇 | CAS号158980-57-5 tert-butyl 4-br... | CAS号158585-09-2 3,5-双(苄氧基)-4-溴苯甲酸苄酯 | CAS号355121-52-7 3,5-BIS-(ALLYLO... | CAS号34126-16-4 4-溴-3,5-二羟基苯甲酸甲酯 | CAS号32156-34-6 1-(4-bromo-3,5-...

📜3,5-二羟基苯甲酸置于溴,溶剂黄146体系中,化学反应 1.5H,反应生成4-溴-3,5-二羟基苯甲酸
参考文献:(+/-)-Taiwaniaquinol B 通过多米诺分子内 Friedel-Crafts 酰化/羰基 α-叔烷基化反应的全合成
标题:(+/-)-Taiwaniaquinol B 通过多米诺分子内 Friedel-Crafts 酰化/羰基 α-叔烷基化反应的全合成
摘要:首次合成 Taiwaniaquinol B,一种 6-Nor-5(6-->7)Abeoabietane 型二萜,具有罕见的融合 6-5-6 三环碳骨架,分 15 个步骤完成.Lewis酸促进的串联分子内friedel-Crafts/羰基α-叔烷基化反应被用作合成空间拥挤的含1-茚满酮三环结构的核心策略.这种多重碳-碳键形成反应利用了 Meldrum 酸的独特反应性.简便的前体合成使其成为空间拥挤的含 1-茚满酮环系统的便利修饰和组装的有用方法.
Doi:10.1021/ja054447P

专利信息

专利号:US-7858809-B2
优先权日:2004-04-12
标题 :Process for production of pyrazole-fused ring derivatives
发明人：NEGI SHIGETO; SHIMIZU TOSHIKAZU; KURODA HIROSHI; SHIMOMURA NAOYUKI; SASHO MANABU; HOSHINO YORIHISA; KUBOTO MANABU
权利人:EISAI R&D MAN CO LTD
摘要:Intermediates useful for the synthesis of pyrazole-fused ring derivatives, such as 7-phenylpyrazolo [1,5-a]pyridine derivatives, and method for producing the same. Method for producing compound represented by the general formula (II), wherein Z 1 and Z 2 each independently represents a methine group or a nitrogen atom; R l represents an ethyl group or the like; R 5 represents a hydrogen atom or the like; R 2 and R 3 each independently represents a C 1-6 alkyl group or the like, salts thereof, or solvates of both, comprising the step of: reacting a compound represented by the general formula (I), wherein Z 1 , Z 2 , R 5 , R 1 , R 2 and R 3 each has the same definition as described above, with an organometallic reagent; and then reacting the resulting product with pentafluoroiodobenzene.

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:US-6797819-B1
优先权日:1998-06-11
标 题 :Alkaloids
发明人：SHAIR MATTHEW; WESTWOOD NICHOLAS; PELISH HENRY EFREM; KIRCHHAUSEN THOMAS; FENG YAN
权利人:HARVARD COLLEGE; CBR INST FOR BIOMED RES INC
摘要:The present invention provides novel alkaloid compounds and collections of these compounds, and provides methods for the synthesis of these compounds using biomimetic synthetic strategies. Additionally, the present invention provides pharmaceutical compositions and methods for treating disorders such as bacterial infections, proliferative diseases, and reproductive disorders, to name a few.

专利号:US-2011152210-A1
优先权日:2009-12-18
标题 :Polyphenol compounds for inhibiting proteasome and uses thereof
发明人：CHAN TAK-HANG; DOU Q PING
权利人:UNIV MCGILL; UNIV HONG KONG POLYTECHNIC; UNIV WAYNE STATE
摘要:Synthetic polyphenolic compounds of formula (I), their modes of synthesis, and pharmaceutical compositions thereof are provided herein. Use of the compounds and compositions described herein for inhibiting proteasomal activity and for treating cancer is also provided.

专利号:US-2014378541-A1
优先权日:2011-06-16
标题 :Synthetic Epigallocatechin Gallate (EGCG) Analogs
发明人：CHAN TAK-HANG; PAMU SREEDHAR; DOU QING PING; CHEN DI
权利人:CHAN TAK-HANG; PAMU SREEDHAR; DOU QING PING; CHEN DI; UNIV WAYNE STATE; UNIV MCGILL; UNIV HONG KONG POLYTECHNIC
摘要:Synthetic polyphenolic compounds of formula (I), their modes of synthesis, and pharmaceutical compositions thereof are provided herein. Use of the compounds and compositions described herein for treating cancer and for treating metabolic disorders is also provided.

专利号:US-12398115-B2
优先权日:2019-04-09
标 题 :Chrysophaentin analogs and use thereof
发明人：SULIKOWSKI GARY A; FULLENKAMP CHRISTOPHER; KIM KWANGHO; JANA SOMNATH
权利人:UNIV VANDERBILT
摘要:Provided are 9-dechlorochrysophaentin analog compounds and the synthesis process thereof. The disclosed compound have remarkable antimicrobial activities that are comparable to, or even more potent than, the natural product chrysophaentin A. Also provided are method of inhibiting bacterial growth or treating bacterial infection by administering an effective amount of the disclosed compounds.