CAS: 136112-00-0; Chloroform,3-Methylbutan-1-Ol,Phenol

专利信息

专利号:US-7402418-B2
优先权日:2001-09-20
标 题:Genes participating in the synthesis of fatty acid having trans-11-,cis-13-conjugated double bond and utilization thereof
发明人：OSUMI MARI; MURASE JUNKO; IMAMURA JUN
权利人:PLANTECH RES INST; INC ADMIN AGENCY NARO
摘要:An object of the present invention is to clone a gene which is involved in synthesis of fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bone at position Δ12. The present invention provides a gene having any one of the following nucleotide sequences:n (A) a nucleotide sequence encoding an amino acid sequence shown in SEQ ID NO: 1 or 12; (B) a nucleotide sequence encoding an amino acid sequence comprising a deletion, addition or substitution of one or several amino acids with respect to the amino acid sequence shown in SEQ NO: 1 or 12, and having an ability of synthesizing fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bond at position Δ12; (C) a nucleotide sequence shown in SEQ ID NO: 2 or 13; (D) a nucleotide sequence comprising a deletion, addition or substitution of one or several nucleotides with respect to the nucleotide sequence shown in SEQ ID NO: 2 or 13, and encoding a protein having an ability of synthesizing fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bond at position Δ12; and (E) a nucleotide sequence hybridizing with the nucleotide sequence shown in SEQ ID NO: 2 or 13 or a complementary sequence thereof under stringent conditions, and encoding a protein having an ability of synthesizing fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bond at position Δ12.

专利号:WO-2004027077-A1
优先权日:2002-09-20
标 题 :Cell-free protein synthesis solution, process for producing the same and utilization of the same
发明人：ISHIKAWA MASAYUKI; NAITO SATOSHI; KOMODA KEISUKE; ISHIBASHI KAZUHIRO
权利人:JAPAN SCIENCE & TECH AGENCY; MASAYUKI ISHIKAWA; NAITO SATOSHI; KOMODA KEISUKE; ISHIBASHI KAZUHIRO
摘要:By using a cell-free protein synthesis solution containing an extract of an extract of devacuolated protoplasts which is prepared by removing vacuoles from cultured plant cell-origin protoplasts and contains intracellular membrane components such as endoplasmic reticulums and Golgi bodies, a post-transcriptional modificaiton, a secretion signal processing, etc. can be reproduced in vitro. Thus, a cell-free protein synthesis solution containing intracellular membrane components enabling post-transcriptional modification, etc., which can be hardly carried out in the existing cell-free protein synthesis systems, a process for producing the same and a method of using the same can be obtained.

专利号:US-2006134779-A1
优先权日:2004-03-10
标题:Modulation of cell intrinsic strain to control cell modulus, matrix synthesis, secretion, organization, material properties and remodeling of tissue engineered constructs
发明人：BANES ALBERT J; QI JIE
权利人:BANES ALBERT J; QI JIE
摘要:The present invention provides methods for manipulating the intrinsic strain of cells by treating tissue engineered constructs or native tissue with compounds which affect the intrinsic strain setpoint of the cells in order to modulate matrix synthesis, secretion, organization and/or remodeling so that the tissues withstand in vivo mechanical forces and have the structural characteristics of host tissue which has been permanently altered by injury, atrophy or disease. The compounds include binding site peptides, ATP, UTP and related analogues, IL-1β, TGF-α, cytochalasin D, hyaluronic acid, nocodazole and others. Also provided are methods for applying a mechanical external strain to the tissues, as well as methods for modulating the expression of cytoskeletal genes that transcribe cytoskeletal proteins which regulate a cell's intrinsic strain setpoint.

专利号:US-2007077653-A1
优先权日:2003-09-04
标 题:Modulation of cell intrinsic strain to control matrix synthesis, secretion, organization and remodeling
发明人：BANES ALBERT J; QI JIE
权利人:MEDTRAIN TECHNOLOGIES LLC
摘要:The present invention provides methods for manipulating the intrinsic strain of cells by treating tissue engineered constructs or native tissue with compounds which affect the intrinsic strain setpoint of the cells in order to modulate matrix synthesis, secretion, organization and/or remodeling so that the tissues withstand in vivo mechanical forces and have the structural characteristics of host tissue which has been permanently altered by injury, atrophy or disease. The compounds include binding site peptides, ATP, UTP and related analogues, IL-1&bgr; TGF-&agr; cytochalasin D, hyaluronic acid, nocodazole and others. Also provided are methods for applying a mechanical external strain to the tissues, as well as methods for modulating the expression of cytoskeletal genes that transcribe cytoskeletal proteins which regulate a cell's intrinsic strain setpoint.

专利号:US-2006269975-A1
优先权日:1999-07-16
标 题:Corynebacterium glutamicum genes encoding proteins involved in DNA replication, protein synthesis, and pathogenesis
发明人：POMPEJUS MARKUS; KROGER BURKHARD; SCHRODER HARTWIG; ZELDER OSKAR; HABERHAUER GREGOR
权利人:BASF AG
摘要:Isolated nucleic acid molecules, designated RRP nucleic acid molecules, which encode novel RRP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing RRP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated RRP proteins, mutated RRP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of RRP genes in this organism.

专利号:US-2005244935-A1
优先权日:1999-06-25
标题:Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport
发明人：POMPEJUS MARKUS; KROGER BURKHARD; SCHRODER HARTWIG; ZELDER OSKAR; HABERHAUER GREGOR
权利人:BASF AG
摘要:Isolated nucleic acid molecules, designated MCT nucleic acid molecules, which encode novel MCT proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MCT nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MCT proteins, mutated MCT proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MCT genes in this organism.