CAS: 76842-07-4; 2',3,3',4,5-Pentachlorobiphenyl
该化合物是多氯联苯(PCB)家族的成员,该家族由以其环境持久性和潜在毒性而闻名的合成有机化学品组成.多氯联苯 122 的特点是其双联体结构,其中两个苯环由一个单一的联结连接,在环上替换多个氯原子.具体地说,多氯联苯 122 共有六个氯原子附着,影响其物理和化学特性,例如其疏水性和耐降解性.该化合物通常被发现为无色的轻黄色液体或固体,视温度和浓度而定.多氯联苯,包括多氯联苯 因其电绝缘特性而闻名,在电气设备中历来有用,但由于对环境和健康的影响,包括潜在的致癌效应和内分泌干扰,这些物质现在基本上被禁止或限制.环境中多氯联苯污染的监测和补救由于其在食物链中的长半衰期和生物累积性,仍然十分关键.
- 英文名称2',3,3',4,5-Pentachlorobiphenyl
- 中文名称2',3,3',4,5-五氯联苯
- IUPAC名称1,2,3-trichloro-5-(2,3-dichlorophenyl)benzene
- 其它别名2,3,3',4',5'-Pentachlorobiphenyl; 2',3,3',4,5-Pentachlorobiphenyl
- CAS编号76842-07-4
- MFCD编号:MFCD00152728
- FDA UNII编号:S3SUI921T4
- 分子式:C12H5Cl5分子量:326.43
- 产品CID: 1760952
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: GWOWBISZHLPYEK-UHFFFAOYSA-N
- 1S/C12H5Cl5/c13-8-3-1-2-7(11(8)16)6-4-9(14)12(17)10(15)5-6/h1-5H
- 计算化学: 氢键受体数*氢键供体数*可旋转键数1.0
物理性质
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
1,2-dichloro-benzene 3,4,5-trichloroaniline 1,2-Dichloro-3-iodobenzene 1,2,3-trichloro-5-iodobenzene合成工艺路线路线简述
📜2,3-二氯碘苯,1,2,3-三氯-5-碘苯置于铜体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应生成 2',3,3',4,5-五氯联苯
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
DOI:10.1016/0045-6535(95)00140-4
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.
摘要:T6: World Health Organization (1993). Environ Health Criteria 140: Polychlorniated Biphenyls and Terphenyls.
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