CAS: 6592-85-4; Hydrastinine
该化合物是来自九头蛇甘蓝(Hydrystis Canadensis)植物(俗称金色)的碱性碱,其特征为结构特征,包括管状环和氢氧基,有助于其生物活动.九头蛇以其潜在的药理效应而著称,包括抗微生物和抗炎特性;已就其在传统医学中的作用进行了研究,特别是在草药疗法中.该物质一般是白到白的晶状粉,在水和酒精中溶解,便于其从植物来源提取.其化学行为受到功能组的存在的影响,使其在一定条件下具有反应性.九头蛇的安全和毒性是持续研究的主题,强调了解其在医药应用中的影响的重要性.
- ⚠️《化妆品禁用原料目录》
- 英文名称Hydrastinine
- 中文名称北美黄连次碱
- IUPAC名称6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-ol
- 其它别名Hydrastinine; 5,6,7,8-Tetrahydro-6-Methyl-1,3-Dioxolo[4,5-G]Isoquinolin-5-Ol; Hydraztinine; 1,3-Dioxolo[4,5-G]Isoquinolin-5-Ol, 5,6,7,8-Tetrahydro-6-Methyl-
- CAS编号6592-85-4
- MFCD编号:MFCD00179051
- EINECS号:229-533-9
- FDA UNII编号:V1I0L48X6E
- 分子式:C11H13NO3分子量:207.23
- 产品CID: 1640210
- 产品分类有机原料 → 有机杂环化合物 → 四氢异喹啉
物理性质
MSDS等安全信息
- 警示词warning
- 危险描述H303 May be harmful if swallowed+H313 Skin contact may be harmful+H333 Inhalation may be harmful to the body
- 防范说明P264Thoroughly clean after treatmentP280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective maskP305If it enters the eyesP351Rinse carefully with water for a few minutesP338Remove the contact lens(If any)And easy to operate,Continue flushingP337If eye irritation persistsP313Obtain medical advice/care
- 危险等级6.1(b)
- UN编号1544
- 包装等级III
- 安全声明H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
上下游产品
氢乙种北美黄连碱 N-Methyl-6,7-Methylenedioxy-1,2,3,4-Tetrahydroisoquinoline 494-55-3氧化白毛茛分碱 Oxyhydrastinine 552-29-4
5-(3,4-Dimethoxy-2-Styryl-Benzyl)-6-Methyl-5,6,7,8-Tetrahydro-[1,3]Dioxolo[4,5-G]Isoquinoline 62404-98-2
合成工艺路线路线简述
📜北美黄连碱 反应生成 北美黄连次碱
参考文献:Holland,H.L. Et Al.,Canadian Journal Of Chemistry,1979,Vol. 57,P. 1588-1597
标题:Holland,H.L. Et Al.,Canadian Journal Of Chemistry,1979,Vol. 57,P. 1588-1597
海关参考信息
- 2902600000-乙苯
2905110000-甲醇
2906210000-苄醇
2907210001-间苯二酚 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.
专利号:US-10814013-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A1
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:US-2008107598-A1
优先权日:2006-10-05
标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications
专利号:AU-2007308022-B2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1. Inbaraj JJ, Kukielczak BM, Bilski P, He YY, Sik RH, Chignell CF. Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.). 2. Palmatine, hydrastine, canadine, and hydrastinine. Chem Res Toxicol. 2006 Jun;19(6):739-44. doi: 10.1021/tx050356u.合成参考文献
参考文献:10.1021/tx050356u
摘要:Inbaraj JJ, Kukielczak BM, Bilski P, He YY, Sik RH, Chignell CF. Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.). 2. Palmatine, hydrastine, canadine, and hydrastinine. Chem Res Toxicol. 2006 Jun;19(6):739–44. doi: 10.1021/tx050356u.
📝 需求与反馈
尽可能描述清楚需求与问题信息
