📜苯并-18-冠-6-醚,三氟乙酸置于乌洛托品,盐酸体系中,化学反应 26.83H,以70%的收率获得产物4'-羧基苯并-18-冠6-醚 参考文献:Sequential Energy Transfer Followed By Electron Transfer In A Bodipy-bisstyrylbodipy Bound To C60 Triad Via A 'two-Point' Binding Strategy 标题:Sequential Energy Transfer Followed By Electron Transfer In A Bodipy-bisstyrylbodipy Bound To C60 Triad Via A 'two-Point' Binding Strategy 摘要:在一个自组装的,宽带捕获三元体中,展示了逐步能量转移后电子转移发生,导致产生一个电荷分离状态,这类似于光合作用天线反应中心的模拟. DOI:10.1039/c7Cc08063H
专利号:US-7683025-B2 优先权日:2002-11-14 标 题:Synthesis and self-assembly of ABC triblock bola peptide amphiphiles 发明人:STUPP SAMUEL I; CLAUSSEN RANDAL C; RABATIC BRYAN M 权利人:UNIV NORTHWESTERN 摘要:The present invention provides for bola amphiphiles compositions which have more than one lyophilic (hydrophilic) head group and a hydrophobic (hydrophobic) moiety capable of hydrogen bonding with other bola amphiphiles. These bola amphiphiles are capable of self assembling into micelles. The advantage of these bola amphiphiles is that they may self-assemble into micelles whose lyophilic head groups are located within the core and on the surface of the micelles. The lyophilic environment at the core and on the surface of the micelles may be different and may be controlled by the choice of head group moieties on the bola amphiphiles. The utility of these compositions is that they can be used to load or encapsulate polar drugs, DNA, mineralizable inorganic salts, or other molecules of interest within the polar interior of the micelle. Such compositions may also provide small water-filled ion-conducting channels within their structure suitable for use in micro electromechanical devices, as templates for nanowires or dielectrics, and as chemical sensors.
专利号:US-9073802-B2 优先权日:2010-02-12 标题 :Method for producing 18F-labeled compound and high molecular compound to be used in the method 发明人:TAKAHASHI TAKASHI; TANAKA HIROSHI; NAKADA TSUTOMU 权利人:TAKAHASHI TAKASHI; TANAKA HIROSHI; NAKADA TSUTOMU; TOKYO INST TECH; UNIV NIIGATA 摘要:The present invention aims at solving the problems of conventional methods for producing an 18 F-labeled compound, that is, the problem of purification of a compound in a liquid phase synthesis method and the problem of an insufficient yield due to the reduction of reactivity in a solid phase synthesis method. There is provided a method for producing an 18 F-labeled compound including: allowing a high molecular compound containing a residue of a precursor compound to be labeled and a residue of a phase transfer catalyst in the molecule thereof to react with 18 F − ; and removing the 18 F-labeled compound from the high molecular compound.
专利号:ES-2686136-A1 优先权日:2017-03-29 标题 :SYNTHESIS PROCEDURE OF 9,10-BIS (CHLOROMETHYL) ANTHRACEN (Machine-translation by Google Translate, not legally binding)
专利号:US-2006110437-A1 优先权日:2002-11-14 标 题 :Synthesis and self-assembly of abc triblock bola peptide
1: Yokoyama T, Mizuguchi M. Crown Ethers as Transthyretin Amyloidogenesis Inhibitors. J Med Chem. 2019 Feb 28;62(4):2076-2082. doi: 10.1021/acs.jmedchem.8b01700. Epub 2019 Feb 8.
合成参考文献
参考文献:10.1016/j.bbrc.2023.08.050 摘要:Ikeda Y, Davis MI, Sumita K, Zheng Y, Kofuji S, Sasaki M, Hirota Y, Pragani R, Shen M, Boxer MB, Takeuchi K, Senda T, Simeonov A, Sasaki AT. Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells. Biochemical and Biophysical Research Communications. 2023 Oct;679():116–21. doi: 10.1016/j.bbrc.2023.08.050.