专利号:WO-0063152-A1 优先权日:1999-02-22 标题:Acetylated and related analogues of chicoric acid as hiv integrase inhibitors 发明人:BURKE TERRENCE R; ZHAIWEI LIN; ZHAO HE; NEAMATI NOURI; POMMIER YVES 权利人:US HEALTH; BURKE TERRENCE R; ZHAIWEI LIN; ZHAO HE; NEAMATI NOURI; POMMIER YVES 摘要:Chicoric acid analogues and derivatives have activity against HIV-1 integrase. The structural features that are required for this activity are elucidated by assaying these analogues and derivatives against HIV-1 integrase. Furthermore, methods of synthesis of the enantiomers of chicoric acid itself, as well as its analogues and derivatives, are disclosed. Additionally, methods of use of chicoric acid analogues and derivatives to inhibit HIV-1 integrase are disclosed, as are compositions comprising chicoric acid analogues and derivatives.
专利号:CN-101495436-A 优先权日:2006-07-28 标 题:Novel process for the synthesis of -stilbene derivatives which makes it possible to obtain resveratrol and piceatannol
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参考文献:10.1038/s42004-024-01138-x 摘要:Petermeier P, Bittner JP, Jonsson T, Domínguez de María P, Byström E, Kara S. Integrated preservation of water activity as key to intensified chemoenzymatic synthesis of bio-based styrene derivatives. Commun Chem. 2024 Mar 14;7(1):57.