CAS: 429669-07-8; 1-Boc-3-(Methoxy)Azetidine

相似化合物

141699-55-0 148644-09-1 942307-80-4

上下游产品

methyl iodide tert-butyl 3-hydroxyazetidine-1-carboxylate tert-butyl dicarbonatedi-tert-butyl dicarbonate tert-butyl 3-oxoazetidine-1-carboxylate

📜二碳酸二叔丁酯置于sodium Hydride,碳酸氢钠体系中,用 四氢呋喃,水,Mineral Oil 作为反应溶剂,化学反应 0.5H,反应生成 1-Boc-3-甲氧基基氮杂环丁烷
参考文献: Hepatitis C Inhibitor Compounds[fr] Composés Inhibiteurs De L'Hépatite C
标题: Hepatitis C Inhibitor Compounds[fr] Composés Inhibiteurs De L'Hépatite C
摘要:式(i)中的化合物,其中r1,R2,R3,R4和r5如本文所定义,对含有临床相关的基因型1A R155K和基因型1B D168V耐药突变的ns3蛋白酶保持非常好的活性.这些化合物可用作hcv Ns3蛋白酶的抑制剂,用于治疗丙型肝炎病毒感染.

专利信息

专利号:US-9676783-B2
优先权日:2008-10-22
标 题:Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds
发明人：HAAS JULIA; ANDREWS STEVEN W; JIANG YUTONG; ZHANG GAN
权利人:ARRAY BIOPHARMA INC
摘要:Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.

专利号:DK-2725028-T3
优先权日:2008-10-22
标题:Substituted pyrazolo [1,5-a] pyrimidine compounds as intermediates in the synthesis of kinase inhibitors TRK

专利号:EP-2725028-A1
优先权日:2008-10-22
标题 :Substituted pyrazolo[1,5-]pyrimidine compounds as intermediates in the synthesis of TRK kinase inhibitors

专利号:EP-2725028-B1
优先权日:2008-10-22
标题 :Substituted pyrazolo[1,5-]pyrimidine compounds as intermediates in the synthesis of TRK kinase inhibitors

专利号:HU-E030413-T2
优先权日:2008-10-22
标 题:Substituted pyrazolo[1,5-]pyrimidine compounds as intermediates in the synthesis of TRK kinase inhibitors

专利号:ES-2588504-T3
优先权日:2008-10-22
标题 :Pyrazolo [1,5-a] pyrimidine compounds substituted as intermediates in the synthesis of TRK kinase inhibitors