CAS: 2612-57-9; 2,4-Dichlorophenylisocyantae

该化合物是有机化合物,其特性是附于二氯苯基混合物的异丙氰酸性功能组,通常看起来是无色的,可粉黄液,有刺鼻的气味,这种化合物以反应性为名,特别是核糖核素,在合成各种有机化合物,包括制药和农用化学物方面有用,有机溶剂中中中可中度溶解,但水溶解性有限.由于异丙酸酯组的存在,它可能是危险的,对皮肤,眼睛和呼吸系统具有刺激性.在通风良好的地区适当处理和储存适当的个人防护设备对于减轻接触风险至关重要.此外,2,4-二氯异丙烯受管制,因为其使用和处置可能对环境产生影响和毒性.

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5392-82-5 34893-92-0 2740-81-0

物理性质

MSDS等安全信息

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REACH注册ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号75-44-5 光气 | CAS号554-00-7 2,4-二氯苯胺 | CAS号2447-79-2 2,4-二氯苯甲酰胺 | CAS号32315-10-9 三光气 | CAS号103-71-9 异氰酸苯酯 | CAS号102-07-8 |N|,|N|'-二苯基脲 | CAS号7782-50-5 氯气 | CAS号36441-29-9 14-(phenyl)-14H... | CAS号79-34-5 四氯乙烷 | CAS号5310-94-1 1-(2,4-dichloro... | CAS号55268-52-5 1,3-bis(2,4-dic...

合成工艺路线路线简述

    📜双苯基脲置于氯,1,1,2,2-四氯乙烷,1-氯萘体系中,化学反应生成2,4-二氯苯基异氰酸酯
    参考文献:Siefken,Justus Liebigs Annalen Der Chemie,1949,Vol. 562,P. 75,1114
    标题:Siefken,Justus Liebigs Annalen Der Chemie,1949,Vol. 562,P. 75,1114

    海关参考信息

    专利信息


    专利号:US-7138526-B1
    优先权日:1999-06-15
    标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
    发明人：HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
    权利人:AVENTIS PHARMA INC
    摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries

    专利号:US-4578514-A
    优先权日:1984-11-01
    标题 :Synthesis of sulfilimines
    发明人：GETMAN DANIEL P
    权利人:MONSANTO CO
    摘要:Processes are disclosed for preparation of N-aryl-S,S-dihydrocarbylsulfilimines by reaction of phenylisocyanate compounds with hydrocarbyl sulfoxides. The sulfilimines can be rearranged to ortho-thioalkylene anilines and the reactions can be employed in a route for converting nitrobenzene compounds to ortho-thioalkylene anilines, which are useful intermediates for preparation of herbicidal compounds.

    专利号:US-2005192265-A1
    优先权日:2003-03-20
    标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
    摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:US-6906056-B2
    优先权日:1998-06-22
    标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
    发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
    权利人:LILLY CO ELI
    摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:US-10570179-B2
    优先权日:2016-09-02
    标 题:Substituted urea depsipeptide analogs as activators of the CLPP endopeptidase
    发明人：LEE RICHARD E; ZHAO YING
    权利人:ST JUDE CHILDRENS RES HOSPITAL
    摘要:In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

    专利号:DD-287715-A5
    优先权日:1989-09-13
    标 题 :PROCESS FOR SYNTHESIS OF SUBSTITUTED 3- (N-ARYL-CARBAMOYL) -BZW. 3- (N-cycloalkyl-carbamoyl) -2-methylthio-3,4-dihydroquinazolines

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    合成参考文献


    摘要:Álvarez, M.; Joule, J. A., Science of Synthesis, (2005) 15, 875.
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