CAS: 1004-39-3; 4,6-Diaminopyrimidine-2-Thiol

该化合物是一种有机化合物,其特点是其火水环结构,在4和6个位置上有两个氨基氨基化合物组(-NH2),在2个位置上有一个硫醇组(-SH),该化合物一般是白到光黄色晶体状固体,由于氨基和硫醇组的存在,可溶于水中,可进行氢结合;已知其作为各种药物和农用化学品合成中间体的作用;氨基和甲卡普托功能组的存在允许多种再活动,使其成为有机合成中有价值的建筑块;此外,4,6-Diamino-2-丙二甲基丙胺可展示生物活动,包括潜在的抗微生物特性,尽管具体应用可能有所不同;应参考安全数据,如任何化学数据,以了解其处理和潜在危害.

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上下游产品

thiourea malononitrile sodium ethanolate 2-benzoylthio-4,6-diaminopyrimidine 2-(ethylthio)pyrimidine-4,6-diamine 5-(4-chloro-phenylazo)-2-(4-chloro-phenylsulfanyl)-pyrimidine-4,6-diyldiamine (4,6-diamino-pyrimidin-2-ylmercapto)-acetic acid 4,6-diamino-2-methylthiopyrimidine

合成工艺路线路线简述

    4,6-Diamino-1-Benzoylamino-1H-Pyrimidine-2-Thione置于甲醇体系中,化学反应 0.25H,以100%的收率获得4,6-二氨基-2-巰基嘧啶
    参考文献:Chemical Properties Of Acylated Derivatives Of 4,6-Diamino-2-Mercaptopyrimidine
    标题:Chemical Properties Of Acylated Derivatives Of 4,6-Diamino-2-Mercaptopyrimidine
    摘要:
    Doi:10.1007/bf00949231

    专利信息


    专利号:US-2012184724-A1
    优先权日:2009-09-22
    标 题 :Protected monomers and methods of deprotection for rna synthesis
    发明人:SIERZCHALA AGNIESZKA B; SMART BRIAN PHILLIP; DELLINGER DOUGLAS J; DELLINGER GERALDINE; MYERSON JOEL; TIMAR ZOLTAN
    权利人:SIERZCHALA AGNIESZKA B; SMART BRIAN PHILLIP; DELLINGER DOUGLAS J; DELLINGER GERALDINE; MYERSON JOEL; TIMAR ZOLTAN; AGILENT TECHNOLOGIES INC
    摘要:A nucleoside monomer that is protected by a thionocarbamate protecting group and contains one or more 2 H, 13 C, or 15 N isotopes in the ribose and/or base part is provided, as well as a method for making a polynucleotide that uses the same. Also provided is a polynucleotide synthesis method that employs a diamine to deprotect a protected polynucleotide.

    专利号:US-5215987-A
    优先权日:1990-04-23
    标题:Substituted benzhydryl 2-hydroxypropyl piperazine derivatives
    发明人:HAJOS ZOLTAN G; KANOJIA RAMESH M; PRESS JEFFREY B
    权利人:ORTHO PHARMA CORP
    摘要:Substituted benzhydryl 2-hydroxypropyl piperazine derivatives and methods of synthesis of the derivatives are described. The substituted benzhydryl 2-hydroxypropyl piperazine derivatives are useful as cardiotonic agents.

    专利号:US-4603129-A
    优先权日:1980-02-23
    标 题:Cephalosporin derivatives
    发明人:BLUMBACH JUERGEN; DUERCKHEIMER WALTER; SEEGER KARL
    权利人:HOECHST AG
    摘要:What are disclosed are cephalosporin compounds of the formula ##STR1## pharmaceutical preparations which are active against bacterial infections and in which these cephem compounds are present, process for the preparation of the cephem compounds and of the pharmaceutical preparations, use of the cephem compounds for combating bacterial infections, and compounds used as starting materials in the synthesis of said cephem compounds.

    专利号:US-5612468-A
    优先权日:1994-05-18
    标题:Pteridine nucletide analogs as fluorescent DNA probes
    发明人:HAWKINS MARY E; PFLEIDERER WOLFGANG; DAVIS MICHAEL D; BALIS FRANK
    权利人:US HEALTH
    摘要:The invention provides novel pteridine nucleotides which are highly fluorescent under physiological conditions and which may be used in the chemical synthesis of fluorescent oligonucleotides. The invention further provides for fluorescent oligonucleotides comprising one or more pteridine nucleotides. In addition the invention provides for pteridine nucleotide triphosphates which may be used as the constituent monomers in DNA amplification procedures.

    专利号:RU-2098420-C1
    优先权日:1993-09-11
    标 题:Cephalosporin compounds, their pharmaceutically acceptable nontoxic salts, physiologically hydrolyzable esters, isomers having e-configuration of double bond in propenyl group, syn-isomers and optical isomers and a method of their synthesis
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    合成参考文献


    摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 176.
    摘要:T. Okano and S. Kojima. J. Pharm. Soc. (Japan) 86, 547 (1966).
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