CAS: 6795-87-5; 2-Methoxybutane

该化合物是分子式C5H12O(SBME)的明显挥发性醚,主要用作有机合成和工业应用的溶剂,因为其有利特性,包括中极性,低水溶性,以及普通有机溶剂的可不良.SBME与其他醚相比,其沸点相对较高,提高了其在需要控制蒸发率的反应中的效用.在典型反应条件下的稳定性和形成过氧化物的低趋势有助于更安全的处理.此外,SBME在燃料配制中被用作氧剂,提高燃烧效率,同时减少排放.其平衡的物理和化学特性使它在实验室和工业环境中成为多用途的选择.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

oxirane methanol 1-butyl-1-nitrosourea trimethylene oxide methanol isobutene tert-butyl methyl ether benzoic acid methyl ester

合成工艺路线路线简述

    📜2-碘-3-甲氧基-丁烷置于cobalt-Nickel,Alkaline Solution体系中,化学反应生成 甲基仲丁基醚
    参考文献:Dolliver Et Al.,Journal Of The American Chemical Society,1938,Vol. 60,P. 441
    标题:Dolliver Et Al.,Journal Of The American Chemical Society,1938,Vol. 60,P. 441

    海关参考信息

    专利信息


    专利号:US-11926589-B2
    优先权日:2019-07-09
    标 题 :Process for the synthesis of non-racemic cyclohexenes
    发明人:REISMAN SARAH; ROMBOLA MICHAEL; LADD CAROLYN L; MCLAUGHLIN MARTIN JOHN; ZUEND STEPHAN; GOETZ ROLAND
    权利人:BASF CORP; CALIFORNIA INST OF TECHN
    摘要:This invention relates to a process for the synthesis of a non-racemic cyclohexene compound of formula (I) by a Diels-Alder reaction of a compound of formula (II) with a compound of formula (III) wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 and Y have the meanings as defined in the description in the presence of a catalyst comprising at least one m-valent metal cation M m+ wherein the metal M is selected from Scandium (Sc), Yttrium (Y), Lanthanum (La), Cerium (Ce), Praseodymium (Pr), Neodymium (Nd), Promethium (Pm), Samarium (Sm), Europium (Eu), Gadolinium 15 (Gd), Terbium (Tb), Dysprosium (Dy), Holmium (Ho), Erbium (Er), Thulium (Tm), Ytterbium (Yb), Lutetium (Lu), Gallium (Ga) and Indium (In), and m is an integer of 1, 2 or 3, and a chiral ligand of the formula (IV) wherein R 10a , R 10b , R 10c , R 10d , R 10a′ , R 10b′ , R 10c′ , R 10d′ , Z and Z′ have the meanings as defined in the description.

    专利号:US-2013338369-A1
    优先权日:2011-03-07
    标 题 :Process for the Synthesis of Aminobiphenylene
    发明人:HEINRICH MARKUS; PRATSCH GERALD
    权利人:HEINRICH MARKUS; PRATSCH GERALD; BASF SE
    摘要:The present invention relates to a process for the synthesis of 2-aminobiphenylene and derivatives thereof by reacting a benzene diazonium salt with an aniline compound under basic reaction conditions.

    专利号:US-6175024-B1
    优先权日:1999-03-03
    标题 :Synthesis of functionalized esters
    发明人:BOYLE JR WILLIAM J; REDDY INDIRA; QIAN ZHENRONG; SU HENG ERIC; RYCKMAN DAVID
    权利人:ALLIED SIGNAL INC
    摘要:A method of preparing an ester of a carboxylic acid functionalized with a moiety selected from the group consisting of halides, sulfonates, ethers, hydroxyl, amines, and aldehydes, said method comprising: (a) providing either a carboxylic acid having a vinyl group or an ester thereof; (b) functionalizing the vinyl carbon closest to the carboxyl group with said moiety, wherein said functionalizing comprises cleaving said vinyl group.

    专利号:US-5663342-A
    优先权日:1994-03-08
    标 题 :2-chloro and 2-bromo derivatives of 1,5-iminosugars
    发明人:BARTA THOMAS E; MUELLER RICHARD A
    权利人:SEARLE & CO
    摘要:Novel 2-chloro and 2-bromo derivatives of 1,5-iminosugars are disclosed, especially such derivatives of 1,5-dideoxy-1,5-imino-D-glucitol. These compounds are useful inhibitors of glucosidase enzymes and also are useful as antiviral agents and as intermediates for the synthesis of other enzyme inhibitors and antiviral compounds.

    专利号:US-9453037-B2
    优先权日:2011-07-28
    标 题 :Methylphenidate-prodrugs, processes of making and using the same
    发明人:GUENTHER SVEN; CHI GUOCHEN; BERA BINDU; MICKLE TRAVIS; BERA SANJIB
    权利人:KEMPHARM INC; KEMPHARM INC
    摘要:The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker. The present technology also relates to the synthesis of methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof or combinations thereof.

    专利号:US-5354772-A
    优先权日:1982-11-22
    标 题:Indole analogs of mevalonolactone and derivatives thereof
    发明人:KATHAWALA FAIZULLA G
    权利人:SANDOZ PHARMACEUTICALS CORP
    摘要:Compounds of the formula wherein one of R and Ro is and the other is primary or secondary C1-6alkyl not containing an asymmetric carbon atom, C3-6cycloalkyl or phenyl-(CH2)m-, wherein R4 is hydrogen, C1-3alkyl, n-butyl, i-butyl, t-butyl, C1-3alkoxy, n-butoxy, i-butoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, R5 is hydrogen, C1-3alkyl, C1-3alkoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, R5a is hydrogen, C1-2alkyl, C1-2alkoxy, fluoro or chloro, and m is 1, 2 or 3, with the provisos that both R5 and R5a must be hydrogen when R4 is hydrogen, R5a must be hydrogen when R5 is hydrogen, not more than one of R4 and R5 is trifluoromethyl, not more than one of R4 and R5 is phenoxy, and not more than one of R4 and R5 is benzyloxy, R2 is hydrogen, C1-3alkyl, n-butyl, i-butyl, t-butyl, C3-6cycloalkyl, C1-3alkoxy, n-butoxy, i-butoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, R3 is hydrogen, C1-3alkyl, C1-3alkoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, with the provisos that R3 must be hydrogen when R2 is hydrogen, not more than one of R2 and R3 is trifluoromethyl, not more than one of R2 and R3 is phenoxy, and not more than one of R2 and R3 is benzyloxy, X is -(CH2)n- or -CH=CH-, wherein n is 0, 1, 2 or 3, and Z is wherein R6 is hydrogen or C1-3alkyl, and R7 is hydrogen, R7b or M, wherein R7b is a physiologically acceptable and hydrolyzable ester group, and M is a pharmaceutically acceptable cation, the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level, and therefore, in the treatment of hyperliopoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Galczynski, J.; Huang, H.; Lambert, T. H., Science of Synthesis: Special Topics, (2021) 1, 332.
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