📜四氢吡咯,3,6-二氯哒嗪置于potassium Carbonate体系中,用 甲苯 作为反应溶剂,化学反应生成 3-氯-6-吡咯烷-1-基-哒嗪 参考文献:Delta 1-Pyrrolines Used As Pesticides 标题:Delta 1-Pyrrolines Used As Pesticides 摘要:化合物(i)的分子式为novel &dgr;1-吡咯烯,其中r1,R2,R3,M和q的含义如描述中所述,多种制备这些物质的过程以及它们用于控制害虫的用途.
专利号:US-8404670-B2 优先权日:2009-02-11 标题:Histamine H3 inverse agonists and antagonists and methods of use thereof 发明人:CHYTIL MILAN; ENGEL SHARON R; FANG QUN KEVIN; SPEAR KERRY L 权利人:CHYTIL MILAN; ENGEL SHARON R; FANG QUN KEVIN; SPEAR KERRY L; SUNOVION PHARMACEUTICALS INC 摘要:Provided herein are fused imidazolyl compounds, methods of synthesis, and methods of use thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders and metabolic disorders. Compounds provided herein inhibit the activity of histamine H3 receptors and modulate the release of various neurotransmitters, such as histamine, acetylcholine, norepinephrine, and dopamine (e.g. at the synapse). Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.