CAS: 6622-54-4; 3-(9H-Carbazol-9-yl)Propanoic Acid

该化合物是一种有机化合物,其独特结构特征为:碳氨酸,包括一种与丙基酸组相连的碳氨酸碱,该化合物一般是白色的,是非白色固体的,因其有趣的电子特性而以其在制药和有机电子产品中的潜在用途而著称;碳氨酸环的存在有助于其稳定性和参加各种化学反应的能力,包括涉及电子转移的化学反应. 9-碳氨丙酸也因其作为较复杂的有机分子合成中的一个构件所具有的潜力而得到承认,其溶性因溶剂不同而不同,而且可能表现出中度或低溶性.此外,该化合物可能拥有生物活动,使其成为医药化学的一个对象.与许多有机化合物一样,在处理时应采取安全防范措施,因为如果摄入或吸入,可能会对健康造成危害.

结构式图片

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上下游产品

CAS号5337-01-9 3-(9H-咔唑-9-基)丙腈 | CAS号539-74-2 3-溴丙酸乙酯 | CAS号86-74-8 咔唑 | CAS号10257-99-5 5,6-dihydro-4h-...

合成工艺路线路线简述

    📜咔唑置于水,苄基三甲基氢氧化铵,Sodium Hydroxide体系中,用 甲醇 作为反应溶剂,化学反应 17.0H,反应生成 3-咔唑丙酸
    参考文献:Peptide Chemistry Applied To A New Family Of Phenothiazine-Containing Inhibitors Of Human Farnesyltransferase
    标题:Peptide Chemistry Applied To A New Family Of Phenothiazine-Containing Inhibitors Of Human Farnesyltransferase
    摘要:Novel Phenothiazine Derivatives Bearing An Amino Acid Residue Were Synthesized Via Peptide Chemistry,And Evaluated For Their Inhibitory Potential On Human Farnesyltransferase. The Phenothiazine Unit Proved To Be An Important Bulky Unit In The Structure Of The Synthesized Inhibitors. Propargyl Ester 20 Bearing A Tyrosine Residue Exhibited The Best Biological Potential In Vitro In The Present Study. Further Syntheses And Biological Evaluation Of Phenothiazine Derivatives Are Necessary In Order To Gain A Full View Of Sar In This Family Of Farnesyltransferase Inhibitors. (C) 2014 Elsevier Ltd. All Rights Reserved.
    DOI:10.1016/j.Bmcl.2014.04.102

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    专利信息


    专利号:AU-1342901-A
    优先权日:1999-10-29
    标 题 :Endogenous nitric oxide synthesis under conditions of low oxygen tension

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    主要参考文献

    参考标题:Modern Friedel-Crafts Chemistry. Part 32. Facile Synthesis Of Some New Fused Heteropolycycles Via Direct Intramoleclar Friedel-Crafts Cyclialkylations Of Suitable Heteroarylalkanols
    作者:Ali Ali Khalaf,Ahmed M. El-Khawaga,Ibrahim M. Awad,Hassan A. K. Abd El-Aal
    摘要:For The Synthesis Of Some Novel Fused Heteropolycycles. Thus, A Variety Of Fused Di-, Tri- And Tetracyclic Nitrogen And Nitrogen-Sulfur Heteropolycycles 8, 9, 11-15 Were Smoothly Synthesized By Friedel-Crafts Intramolecular Alkylations Of Heteroarylalkanols 1-7 In The Presence Of Both Bronsted (Ppa And Ptsa) And Lewis (Alcl3/ch3No2) Acid Catalysts. The Precursor Alkanols Were Readily Prepared By Reaction

    合成参考文献


    参考文献:10.1007/s10570-024-05959-w
    摘要:Wang W, Wang F, Wang Y, Zhang L, Okamoto Y, Shen J. Synthesis of Bulky Cellulose Derivatives for Efficient Enantioselective Fluorescent Sensing. Cellulose. 2024 May 21;31(9):5779–94. doi: 10.1007/s10570-024-05959-w.
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