CAS: 599-67-7; 1,1-Diphenylethanol

上下游产品

4-methyleneoxetan-2-one diethyl ether methyl magnesium iodide benzophenone r)-1,2,3,4,4a,5,6,7-°Ctahydro-1t,4t-etheno-naphthalene-2t,3t,5t,6t-tetracarboxylic acid-2,3;5,6-dianhydride(+/-)-8-phenyl-(4ar)-1,2,3,4,4a,5,6,7-°Ctahydro-1t,4t-etheno-naphthalene-2t,3t,5t,6t-tetracarboxylic acid-2,3;5,6-dianhydride 1-methoxy-1,1-diphenylethane 1-[2-(1,1-diphenyl-ethoxy)-ethyl]-piperidine oxalic acid bis-(1,1-diphenyl-ethyl ester)

2,2-二苯基丙酸置于sodium Tetrahydroborate,[ir(Df(Cf3)Ppy)2(Dtbbpy)](Pf6),氧气,Caesium Carbonate体系中,用 二氯甲烷 作为反应溶剂,化学反应 40.0H,以76%的收率获得产物1,1-二苯基乙醇
参考文献:羧酸光催化脱羧羟基化反应的一般方法
标题:羧酸光催化脱羧羟基化反应的一般方法
摘要:通过使用分子氧作为绿色氧化剂的可见光诱导的光催化作用,开发了一种用于羧酸脱羧羟基化的通用方法.原位添加nabh 4可以减少不稳定的过氧自由基中间体,大大扩大了底物的范围.不同的含sp 3碳的羧酸已成功地用作底物,包括苯乙酸型底物以及脂肪族羧酸.该转化在伯,仲和叔羧酸上可以顺利进行.
DOI:10.1021/acs.Joc.0C00312

专利信息

专利号:US-8759555-B2
优先权日:2004-03-18
标 题:Stereoselective synthesis of vitamin D analogues
发明人：SABROE THOMAS PETER; CALVERLEY MARTIN JOHN
权利人:SABROE THOMAS PETER; CALVERLEY MARTIN JOHN; LEO PHARMA AS
摘要:The present invention relates to intermediates useful for the synthesis of calcipotriol or calcipotriol monohydrate, to methods of producing said intermediates, and to methods of stereoselectively reducing said intermediates.

专利号:US-8410267-B2
优先权日:2008-11-27
标 题 :Regioselective reduction of fused pyrrolocarbazoles-5,7-diones
发明人：PRAT-LACONDEMINE LAURENCE
权利人:PRAT-LACONDEMINE LAURENCE; TEVA SANTE
摘要:The present invention relates to a method for regioselectively reducing the maleimide compounds of formula (I). The invention also relates to C 7 hydroxy lactam regioisomers of formula (II) obtainable by this method and their use for the preparation of lactams of formula (III) which are particularly useful as intermediate for the synthesis of fused pyrrolocarbazoles.

专利号:US-4209464-A
优先权日:1977-06-10
标题:Novel synthesis of 3-amino-2-methylbenzotrifluoride from N-(2-X-5-trifluoromethylphenyl)-S,S-dimethylsulfimide
发明人：STEINMAN MARTIN; WONG YEE S
权利人:SCHERING CORP
摘要:This invention relates to a novel process for preparing 3-amino-2-methylbenzotrifluoride, and to certain novel intermediates produced by the process. 3-Amino-2-methylbenzotrifluoride is a key intermediate useful in the preparation of valuable therapeutic agents such as, for example, 2-(2-methyl-3-trifluoromethyl)anilino nicotinic acid.

专利号:US-2007232813-A1
优先权日:2006-03-28
标 题:Substituted Cyclohexadienals - Syntheses and Applications
发明人：WATANABE CORAN M H; BENCH BENNIE JOHN
权利人:WATANABE CORAN M H; BENCH BENNIE JOHN
摘要:The present invention is generally directed to the use of L-proline and certain derivatives thereof to catalyze the asymmetric self-condensation of α,β-unsaturated aldehydes to form homodimer and heterodimer cyclohexadienals. Reaction conditions are mild and yet amenable to a variety of different substrates yielding molecules with complex scaffolds from simple precursors. This approach allows for diversification and synthesis of this structural class of compounds in sufficient quantity, purity and enantioselectivity for, e.g., biological investigations and use as fluorescent probes, anti-cancer agents, anti-bacterial agents, and/or anti-fungal agents. The present invention is also generally directed to the cyclohexadienals produced.

专利号:US-7320993-B1
优先权日:1997-12-17
标题 :Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents
发明人：BIEDERMANN ELFI; HASMANN MAX; LOESER ROLAND; RATTEL BENNO; REITER FRIEDEMANN; SCHEIN BARBARA; SEIBEL KLAUS; VOGT KLAUS; WOSIKOWSKI KATJA; SCHEMAINDA ISABEL
权利人:ASTELLAS DEUTSCHLAND GMBH
摘要:The invention relates to new pyridylalkane, alkene, and alkine acid amides substituted with an aryl and/or heteroaryl residue according to the general formula (I), with a saturated or one or several-fold unsaturated hydrocarbon residue in the carboxylic acid group, methods for the synthesis of these compounds, medicaments containing these and their production as well as their therapeutic use, especially as cytostatic agents and immunosuppressive agents, for example in the treatment or prevention of various types of tumors and control of immune reactions such as autoimmune diseases.

专利号:CA-2555260-C
优先权日:2004-03-18
标 题 :Stereoselective synthesis of vitamin d analogues