CAS: 42537-72-4; H-N-Me-Met-Oh

相似化合物

112883-40-6 1152-62-1 2488-15-5

上下游产品

S)-2-bromo-4-methylsulfanyl-butyric acid(S)-2-bromo-4-methylsulfanyl-butyric acid methylamine N-methyl-D-methionineN-methyl-D-methionine S-benzyl-N-methyl-hom°CysteineS-benzyl-N-methyl-hom°CysteineN-methyl-DL-methionineN-methyl-DL-methionine N-Methyl-S-(4,4'-dimethoxy-trityl)-L-hom°Cysteine N-methyl-S-trityl-L-hom°Cysteine

📜(4S)-N-Tert-Butyloxycarbonyl-4-(2-Methylthioethyl)-1,3-Oxazolidin-5-One置于2-[[三(羟甲基)甲基]氨基]乙磺酸,三氟乙酸体系中,用 二氯甲烷 作为反应溶剂,化学反应 3.0H,以75%的收率获得产物n-甲基-L-蛋氨酸
参考文献:Orthogonally Protected Bifunctional Amino Acid
标题:Orthogonally Protected Bifunctional Amino Acid
摘要:本发明涉及新型正交保护氨基酸,它们的生产和用于合成可用于诊断和治疗增殖性疾病,特别是肿瘤疾病的结合化合物.

专利信息

专利号:US-2007167530-A1
优先权日:2003-12-23
标 题:Method for depletion of sulphur and/or compounds containing sulphur from a biochemically produced organic compound
发明人：GERLACH TILL; MELDER JOHANN-PETER; HOFFER BRAM W; MEIER ANTON
权利人:BASF AG
摘要:Method of reducing the concentration of sulfur and/or a sulfur-containing compound in a biochemically prepared organic compound by bringing the respective organic compound into contact with an adsorbent. Ethanol which has a particular specification and can be prepared by the abovementioned method, and its use as solvent, disinfectant, as component in pharmaceutical or cosmetic products or in foodstuffs or in cleaners, as feed in steam reforming processes for the synthesis of hydrogen or in fuel cells, or as building block in chemical synthesis.

专利号:US-10526379-B2
优先权日:2015-06-05
标题:Methods and products for fusion protein synthesis
发明人：HOWARTH MARK
权利人:UNIV OXFORD INNOVATION LTD
摘要:A method of producing a fusion protein is provided. The method includes: a) contacting a first protein with a second protein under conditions that enable the formation of an isopeptide bond between said proteins to form a linked protein; and b) contacting the linked protein from (a) with a third protein under conditions that enable the formation of an isopeptide bond between said third protein and said linked protein to form a fusion protein. Peptide linkers and the use of orthogonal pairs of said linkers in the synthesis of fusion proteins are also provided. Recombinant proteins comprising said linkers, nucleic acid molecules encoding said proteins and linkers, vectors comprising said nucleic acid molecules and host cells comprising said vectors and nucleic acid molecules are also contemplated.

专利号:WO-2008098280-A1
优先权日:2007-02-16
标题:Methods for the synthesis of dicarba bridges in growth hormone peptides
发明人：ROBINSON ANDREA JANE; VAN LIEROP BIANCA; WHELAN AMANDA
权利人:POLYCHIP PHARMACEUTICALS PTY; UNIV MONASH; ROBINSON ANDREA JANE; VAN LIEROP BIANCA; WHELAN AMANDA
摘要:The invention relates to peptides comprising the carboxy terminal sequence of a growth hormone or an analogue of such a peptide in which the disulfide bridge is replaced by a dicarba bridge. Compositions containing such dicarba bridged peptides and method of treating obesity in an animal such as a human comprising administration of such dicarba bridged peptides are also disclosed.

专利号:US-2023313156-A1
优先权日:2020-08-06
标题 :Chemical synthesis of large and mirror-image proteins and uses thereof
发明人：ZHU TING; Fan Chuyao; DENG QIANG; XU YUAN
权利人:UNIV TSINGHUA
摘要:Provided herein is a general method for producing large (more than 400 aa long) D-amino acids proteins, also referred to as mirror image protein (with respect to their naturally occurring L-amino acids counterparts), including RNA/DNA manipulating enzymes, and uses thereof in a wide range of research, practical data storage and medicinal applications.

专利号:US-2023364251-A1
优先权日:2020-08-06
标 题:Methods for the synthesis of protein-drug conjugates
发明人：BORCHARDT ALLEN; HUGHES ROBERT MICHAEL
权利人:CIDARA THERAPEUTICS INC
摘要:The present invention relates to intermediates and methods for synthesizing protein-drug conjugates that can be used for the treatment of diseases and related conditions.

专利号:US-7452701-B2
优先权日:1998-11-24
标 题:Methods for the preparation of β-amino acids
发明人：FREY PERRY A; RUZICKA FRANK J
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Purified β-amino acids are of considerable interest in the preparation of pharmacologically active compounds and industrial precursors. Although enantiomerically pure β-amino acids can be produced by standard chemical synthesis, this traditional approach is time consuming, requires expensive starting materials, and results in a racemic mixture which must be purified further. However, DNA molecules encoding lysine 2,3-aminomutase can be used to prepare β-amino acids by methods that avoid the pitfalls of chemical synthesis. The present invention provides a method of producing enantiomerically pure β-amino acids from α-amino acids comprising catalyzing the conversion of an α-amino acid to a corresponding β-amino acid by utilizing a lysine 2,3-aminomutase as the catalyst.