CAS: 2245-52-5; N,N-Dimethyl-1-(4-Vinylphenyl)Methanamine

上下游产品

CAS号1592-20-7 对氯甲基苯乙烯 | CAS号124-40-3 二甲胺 | CAS号848683-69-2 (4-ethenylpheny...

4-乙烯基苯甲醛,二甲胺置于titanium(Iv) Isopropylate,Sodium Tetrahydroborate体系中,用 甲醇 用作溶剂,化学反应 1.5H,反应生成N-(4-乙烯基苄基)-N,N-二甲胺
参考文献:C−n 和 C−o 亲电试剂之间的还原偶联
标题:C−n 和 C−o 亲电试剂之间的还原偶联
摘要:交叉亲电反应是 Cc 键形成的一个有前景的策略.最近的研究主要集中在与有机卤化物的反应上.在这里,我们报告了 Cn 和 Co 亲电试剂之间的偶联反应,证明了通过 Cn 和 Co 裂解构建 Cc 键的可能性.研发了苄基/芳基铵盐和乙烯基/芳基 Co 亲电试剂之间的几种反应.初步机理研究表明,苄基铵是通过自由基机制活化的.
Doi:10.1021/jacs.9B05224

专利信息

专利号:US-5886104-A
优先权日:1993-06-18
标题 :Grafted cross-linked polyolefin substrates for peptide synthesis and assays
发明人：PEDERSEN WALTHER BATSBERG; ALMDAL KRISTOFFER; WINTHER LARS; BERG ROLF HENRIK
权利人:FORSKNIINGSCENTER RISO
摘要:A solid support for the solid-phase synthesis of peptides or proteins in high yield and in high purity, suited both to the synthesis of a single peptide or protein and to the parallel and substantially simultaneous synthesis of a plurality thereof, is based on a cross-linked polyolefin, especially polyethylene, substrate, the cross-linking having been obtained by irradiation with high energy electrons or γ radiation or treatment with organic peroxide such as benzoyl peroxide, to which substrate are grafted polymer chains such as polystyrene chains which are functionalized with a chemical functionality facilitating the formation of an anchoring linkage between the polymer moiety and another chemical species. The solid support is also suited for use in solid-phase biosystems, notably bioassays, such as immunoassays, DNA hybridization assays or PCR amplification. The grafted chains may bear substituents which are such that the polymer-grafted cross-linked polyolefin substrate is swellable by water or aqueous media, in other words, hydrophilic, which makes the solid support particularly well suited for assays of the ELISA type.