CAS: 2065-00-1; Filicinic Acid

📜2,6-Diacetyl-3,5-Dihydroxy-4,4-Dimethyl-2,5-Cyclohexadien-1-One置于盐酸体系中,用 甲醇 用作溶剂,化学反应生成2,2-二甲基环己烷-1,3,5-三酮
参考文献:Hoefer,K.; Riedl,W.,Justus Liebigs Annalen Der Chemie,1962,Vol. 656,P. 127-130
标题:Hoefer,K.; Riedl,W.,Justus Liebigs Annalen Der Chemie,1962,Vol. 656,P. 127-130

专利信息

专利号:US-7854946-B1
优先权日:2007-05-31
标题:Anti-inflammatory and anti-HIV compositions and methods of use
发明人：HILLWIG MATTHEW LEE
权利人:UNIV IOWA STATE RES FOUND INC
摘要:The metabolic fingerprint and anti-inflammatory activity and anti-HIV activity of H. gentianoides is disclosed. High performance liquid chromatography (HPLC) analysis shows that H. gentianoides contains a family of compounds, including some not previously observed in other Hypericum species. H. gentianoides extracts and fractions from these extracts reduce prostaglandin E2 synthesis in mammalian macrophages and inhibit HIV in infected HeLa cells. The present invention provides extracts and fractions thereof from H. gentianoides for use in pharmaceutical compositions and methods for the treatment or inhibition of inflammation, prostaglandin E-mediated disease, disorder or condition, a cyclooxygenase-mediated disease, disorder or condition, or an HIV infection.