CAS: 133059-43-5; 4-Bromo-3-Fluorobenzaldehyde

上下游产品

CAS号222978-01-0 4-溴-3-氟苄醇 | CAS号133059-44-6 4-溴-3-氟苯腈 | CAS号897016-97-6 4-(3-氟-4-(4,4,5... | CAS号57592-43-5 2-氟联苯基-4-甲醛 | CAS号222978-01-0 4-溴-3-氟苄醇 | CAS号923266-16-4 ethyl 3-(4-brom...

4-溴-3-氟苄醇置于manganese Dioxide体系中,用 氯仿 用作溶剂,化学反应 16.0H,以to Give Product (2.3 G,55%)的收率获得4-溴-3-氟苯甲醛
参考文献:Ortho Aminoamides For The Treatment Of Cancer
标题:Ortho Aminoamides For The Treatment Of Cancer
摘要:式为的化合物是hdac抑制剂.这些化合物可用于治疗人或动物的癌症等疾病.

专利信息

专利号:US-2024309003-A1
优先权日:2021-05-04
标题 :Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN; PANDYA BHAUMIK; KAPLAN ALAN
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2â€?). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-9861636-B2
优先权日:2014-04-29
标题 :Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors
发明人：HE WEI
权利人:HE WEI; ZHEJIANG DTRM BIOPHARMA CO LTD
摘要:Described herein is a novel series of multi-fluoro-substituted pyrazolopyrimidine compounds or salts thereof. These compounds are Bruton's tyrosine kinase (BTK) inhibitors. These compounds may possess better BTK inhibition selectivity and pharmacokinetic properties. Disclosed herein are the synthesis methods of these compounds. Disclosed herein are novel synthesis methods of the multi-fluoro-substituted benzophenone and substituted phenoxy benzene. Also disclosed are pharmaceutical compositions comprising the BTK inhibitors described herein. The present invention also relates to pharmaceutical formulations comprising the compounds described herein as active ingredients. The present invention also includes the therapeutic methods by administering the BTK inhibitors and their formulations to treat and inhibit autoimmune disease, hypersensitivity disease, inflammatory diseases and cancer.

专利号:CN-110483435-A
优先权日:2019-08-30
标 题 :A kind of fluorine-containing benzoxazole liquid crystal compound with large birefringence and its synthesis method