CAS: 856240-62-5; (3Ar,4R,5R,6As)-4-((S,E)-3-Hydroxy-5-Phenylpent-1-En-1-yl)Hexahydro-2H-Cyclopenta[b]Furan-2,5-Diol
- 英文名称(3Ar,4R,5R,6As)-4-((S,E)-3-Hydroxy-5-Phenylpent-1-En-1-yl)Hexahydro-2H-Cyclopenta[b]Furan-2,5-Diol
- 中文名称拉坦前列素中间体
- IUPAC名称(3aR,4R,5R,6aS)-4-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2,5-diol
- 其它别名2H-Cyclopenta[b]Furan-2,5-Diol, Hexahydro-4-[(1E,3S)-3-Hydroxy-5-Phenyl-1-Penten-1-Yl]-, (3Ar,4R,5R,6As)-; 2H-Cyclopenta[b]Furan-2,5-Diol, Hexahydro-4-[(1E,3S)-3-Hydroxy-5-Phenyl-1-Pentenyl]-, (3Ar,4R,5R,6As)-; Bimatoprost Lactol/(3Ar,4R,5R,6As)-4-((S,E)-3-Hydroxy-5-Phenylpent-1-Enyl)Hexahydro-2H-Cyclopenta[b]Furan-2,5-Diol; Bimatoprost Impurity 16; (3Ar,4R,5R,6As)-4-((S,E)-3-Hydroxy-5-Phenylpent-1-En-1-yl)Hexahydro-2H-Cyclopenta[b]Furan-2,5-Diol; (3Ar,4R,5R,6As)-4-((S,E)-3-Hydroxy-5-Phenylpent-1-Enyl)Hexahydro-2H-Cyclopenta[b]Furan-2,5-Diol; Bimatoprost Impurity Q
- CAS编号856240-62-5
- MFCD编号:MFCD09954708
- FDA UNII编号:WM5RQU4N2R
- 分子式:C18H24O4分子量:304.39
- 产品CID: 1853630
- 产品分类分析化学 → 标准品 → 药典标准品和杂质标准品
物理性质
上下游产品
CAS号41639-83-2 拉坦前列腺素(游离酸) | CAS号352276-28-9 拉坦前列腺素内半缩醛 | CAS号130209-82-4 拉坦前列素 | CAS号155206-00-1 比马前列素 | CAS号1163135-95-2 5,6-反式-比马前列素合成工艺路线路线简述
📜(3Ar,4S,5R,6As)-4-(叔-丁基二甲基硅烷基氧基)甲基-5-羟基-六氢-2H-环戊[b]呋喃-2-酮置于咪唑,硫酸,四丁基氟化铵,二异丁基氢化铝,三乙胺,(-)-Diisopinocamphenylborane Chloride,Lithium Chloride,2-碘酰基苯甲酸体系中,用 四氢呋喃,甲醇,水,二甲基亚砜,N,N-二甲基甲酰胺,甲苯 作为反应溶剂,化学反应 23.42H,反应生成 拉坦前列素中间体
参考文献:Process For The Synthesis Of Prostaglandins And Intermediates Thereof
标题:Process For The Synthesis Of Prostaglandins And Intermediates Thereof
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902600000-乙苯
2905122000-异丙醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-7161042-B2
优先权日:2004-01-05
标 题 :Protected diols for prostaglandin synthesis
发明人：CLISSOLD DEREK WYNDHAM; CRAIG STUART WILBERT; GADIKOTA RAJENDRAKUMAR REDDY; HE MIN; JURAYJ JURJUS FAYEZ; KAZERANI SHAHROKH; RANNALA ERWIN; SHARMA PRADEEP KUMAR
权利人:JOHNSON MATTHEY PLC
摘要:A process for the preparation of prostaglandin compounds having the formula (I): n nwherein A is selected from the group consisting of C 1 –C 6 alkyl groups; C 7 –C 16 aralkyl groups wherein an aryl portion thereof is unsubstituted or substituted with one to three substituents selected from the group consisting of C 1 –C 6 alkyl groups, halo and CF 3 ; and (CH 2 ) n OR′ wherein n is an integer from 1 to 3 and R′ represents a C 6 –C 10 aryl group which is unsubstituted or substituted with one to three substituents selected from the group consisting of C 1 –C 6 alkyl groups, halo and CF 3 ; B is selected from OR″ and NHR″ wherein R″ is C 1 –C 6 alkyl groups; and represents a double bond or a single bond, is disclosed. Novel intermediates are also disclosed.
专利号:EP-2495235-A1
优先权日:2011-03-04
标 题 :Process for the synthesis of prostaglandins and intermediates thereof
专利号:EP-2495235-B1
优先权日:2011-03-04
标 题:Process for the synthesis of prostaglandins and intermediates thereof
发明人：MARIANI EDOARDO; ORRU GIANMAURO; MONTORSI MAURO; ANDRIOLO ERIKA; BANDINI MARCO; CONTENTO MICHELE; TOLOMELLI ALESSANDRA
权利人:NEWCHEM S P A
