📜十七腈置于盐酸,Amalgamated Zinc,乙醚体系中,化学反应生成 正三十三烷 参考文献:Kirrmann; Geiger-Berschandy,Bulletin De La Societe Chimique De France,1955,P. 991,993 标题:Kirrmann; Geiger-Berschandy,Bulletin De La Societe Chimique De France,1955,P. 991,993
专利号:US-2013095043-A1 优先权日:2010-06-29 标题 :Synthesis of high-performance iron oxide particle tracers for magnetic particle imaging (mpi) 发明人:BURDINSKI DIRK; BOHLENDER CARMEN; HAEX NICOLE P M 权利人:BURDINSKI DIRK; BOHLENDER CARMEN; HAEX NICOLE P M; KONINKL PHILIPS ELECTRONICS NV 摘要:The present invention relates to a method of forming iron oxide nanoparticles comprising the steps of (a) suspending iron oxide/hydroxide and oleic acid or a derivative thereof in a primary organic solvent; (b) increasing the temperature of the suspension by a defined rate up to a maximum of 340° C. to 500° C.; (c) aging the suspension at the maximum temperature of step (b) for about 0.5 to 6 h; (d) cooling the suspension; (e) adding a secondary organic solvent; (f) precipitating nanoparticles by adding a non-solvent and removing excess solvent; (g) dispersing said nanoparticles in said secondary organic solvent; (h) mixing the dispersion of step (g) with a solution of a polymer; and (i) optionally removing said secondary organic solvent. The present invention further relates to an iron oxide nanoparticle obtainable by the method, the additional modification, encapsulation and decoration of such nanoparticles, as well as the use of the nanoparticles as tracers for Magnetic Particle Imaging (MPI), Magnetic Particle Spectroscopy (MPS).
专利号:US-2013089740-A1 优先权日:2010-06-29 标题:Synthesis and use of iron oleate 发明人:BURDINSKI DIRK; BOHLENDER CARMEN 权利人:BURDINSKI DIRK; BOHLENDER CARMEN; KONINKL PHILIPS ELECTRONICS NV 摘要:The present invention relates to a method of forming an iron oleate complex comprising the steps of: (a) dissolving an oleate in a low-order alcohol solvent at a temperature of about 35° C. to 65° C.; (b) adding a non-polar solvent to the solution of step (a); (c) adding an iron salt dissolved in a low-order alcohol to the solution of step (b); (d) agitating the solution of step (c) at a temperature of about 50° C. for at least 5 min; (e) cooling the reaction mixture of step (d) to a temperature of about 15° C. to 30° C.; (f) optionally filtering the reaction mixture of step (e); (g) separating the non-polar solvent phase from the low-order alcohol phase; (h) washing and drying the non-polar solvent phase; (i) removing volatiles from the non-polar solvent phase of step (h) by evaporation; and (j) mixing the product of step (i) with a polar solvent to yield a solid iron oleate complex. The present invention further relates to an iron oleate complex obtainable by the method of the invention, an iron oleate complex of formula I, the use of the iron oleate complex of the invention as precursor for the preparation of nanoparticles, and a method of forming iron oxide nanoparticles comprising the suspension of iron oxide/hydroxide and the iron oleate complex of the invention.
专利号:CN-102971014-A 优先权日:2010-06-29 标 题 :Synthesis of High Performance Iron Oxide Particle Tracers for Magnetic Particle Imaging (MPI)
专利号:US-9567321-B2 优先权日:2010-05-03 标题 :Aromatic monomers deriving from glycerol units, process for their preparation and use thereof for the preparation of water-soluble conjugated polymers 发明人:SCHIMPERNA GIULIANA; PO′ RICCARDO; PELLEGRINO ANDREA; CALDARARO MARIA 权利人:ENI SPA 摘要:Monomers having formula (I) and process for their synthesis which comprises the etherification reaction of a halogen-derivative (Zâ•?Cl, Br, I) having formula (III) with the hydroxyl group of the glycerol derivative (IV), according to the following scheme:
专利号:WO-2012001579-A1 优先权日:2010-06-29 标 题:Synthesis of high-performance iron oxide particle tracers for magnetic particle imaging (mpi)
专利号:EP-2588145-A1 优先权日:2010-06-29 标题:Synthesis of high-performance iron oxide particle tracers for magnetic particle imaging (mpi)
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