CAS: 56961-25-2; 4-Amino-3,5-Dichlorobenzoic Acid

上下游产品

CAS号150-13-0 对氨基苯甲酸 | CAS号619-45-4 4-氨基苯甲酸甲酯 | CAS号94-09-7 对氨基苯甲酸乙酯 | CAS号98588-83-1 3,5-dichloro-4-... | CAS号62-23-7 对硝基苯甲酸 | CAS号556-08-1 4-乙酰氨基苯甲酸 | CAS号881180-72-9 N-(3.5-dichloro... | CAS号7782-50-5 氯气 | CAS号64-19-7 冰醋酸 | CAS号7647-01-0 盐酸 | CAS号41727-48-4 4-氨基-3,5-二氯苯甲酸甲酯 | CAS号51-39-8 3,4,5-三氯苯甲酸 | CAS号51-36-5 3,5-二氯苯甲酸 | CAS号618-62-2 3,5-二氯硝基苯 | CAS号608-31-1 2,6-二氯苯胺 | CAS号651058-99-0 methyl 3,5-dich... | CAS号74878-32-3 (4-氨基-3,5-二氯苯基)甲醇 | CAS号58991-40-5 4-amino-3,5-dic...

📜对氨基苯甲酸置于盐酸,双氧水,溶剂黄146体系中,用 水 作为反应溶剂,化学反应 4.0H,以60%的收率获得产物4-氨基-3,5-二氯苯甲酸
参考文献:Oxidative Chlorination,Desulphonation,Or Decarboxylation To Synthesize Pharmaceutical Intermediates: 2,6-Dichlorotoluene,2,6-Dichloroaniline,And 2,6-Dichlorophenol
标题:Oxidative Chlorination,Desulphonation,Or Decarboxylation To Synthesize Pharmaceutical Intermediates: 2,6-Dichlorotoluene,2,6-Dichloroaniline,And 2,6-Dichlorophenol
摘要:
DOI:10.1021/op9800515

专利信息

专利号:US-10005720-B2
优先权日:2013-04-05
标题:Compounds useful for the treatment of metabolic disorders and synthesis of the same
发明人：SEXTON JONATHAN Z; BRENMAN JAY E; MUSSO DAVID L
权利人:NORTH CAROLINA CENTRAL UNIV; UNIV NORTH CAROLINA CHAPEL HILL
摘要:The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.

专利号:US-2018370905-A1
优先权日:2013-04-05
标题:Compounds Useful for the Treatment of Metabolic Disorders and Synthesis of the Same

专利号:US-2011152295-A1
优先权日:2008-09-08
标 题:Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：LECLERC JEAN-PHILIPPE; LI CHUN SING; RAMTOHUL YEEMAN K
权利人:LECLERC JEAN-PHILIPPE; LI CHUN SING; RAMTOHUL YEEMAN K
摘要:Heteroaromatic compounds of structural formula I are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.

专利号:US-2011166152-A1
优先权日:2008-10-02
标题 :Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：LECLERC JEAN-PHILIPPE; LI CHUN SING; RAMTOHUL YEEMAN K
权利人:LECLERC JEAN-PHILIPPE; LI CHUN SING; RAMTOHUL YEEMAN K
摘要:Heteroaromatic compounds of structural formula (I) are inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD). The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; Type 2 diabetes; insulin resistance; hyperglycemia; Metabolic Syndrome; neurological disease; cancer; and liver steatosis.

专利号:US-2016046560-A1
优先权日:2013-04-05
标题 :Compounds useful for the treatment of metabolic disorders and synthesis of the same

专利号:WO-2014165816-A1
优先权日:2013-04-05
标 题 :Compounds useful for the treatment of metabolic disorders and synthesis of the same