141-46-8 + 96-26-4 = 551-84-8 + 95-43-2 反应条件:1.1 Catalysts: Fructose-6-Phosphate Aldolase 标题:Engineering The Donor Selectivity Of D-Fructose-6-Phosphate Aldolase For Biocatalytic Asymmetric Cross-Aldol Additions Of Glycolaldehyde 作者:Szekrenyi,Anna; Soler,Anna; Garrabou,Xavier; Guerard-Helaine,Christine; Parella,Teodor; Et Al 参考文献:Chemistry - A European Journal 日期:2014 卷标:20(39) 页码:12572-12583
专利号:US-2022395800-A1 优先权日:2019-11-04 标题:Device for automated synthesis of oligo- and polysaccharides 发明人:SEEBERGER PETER H; DANGLAD FLORES JOSE; LE MAI HOANG KIM; PARDO VARGAS ALONSO; SLETTEN ERIC; SALWICZEK MARIO 权利人:MAX PLANCK GESELLSCHAT ZU RFERDERUNG DER WSS E V; GlycoUniverse GmbH & Co KG&A 摘要:The present invention generally relates to automated synthesis technology, and more particularly, to a device and method for automated synthesis of oligo- and polysaccharides on a solid support. In particular the present invention relates to a device for automated synthesis of oligo- and polysaccharides on a solid support comprising a reaction vessel, a reagent storing component, a reagent delivery system, a cooling device for cooling reaction vessel, and a pre-cooling device for pre-cooling the reagents to be supplied.
专利号:US-2019315790-A1 优先权日:2016-11-11 标题:Synthesis of d-allulose 发明人:KOCH TIMO JOHANNES; KIPPING FLORIAN; BUTZ STEFFEN; LESCH MARCEL; HÄSSLER THOMAS 权利人:PFEIFER & LANGEN GMBH & CO KG 摘要:The invention relates to a process for the synthesis of a product saccharide, preferably of D-allulose from an educt saccharide, preferably from D-fructose under heterogeneous or homogeneous catalysis which includes chemical and/or enzymatic catalysis. The synthesis is performed in at least two reactors that are arranged in series and the reaction product exiting the first reactor is subjected to chromatographic separation before it enters the second reactor. Preferably, the chromatographic separation is integrated in a simulated moving bed.
专利号:EP-0349059-B1 优先权日:1988-06-29 标题:Process for the synthesis of polyol fatty acid polyesters 发明人:WILLEMSE GERARDUS W 权利人:UNILEVER NV; UNILEVER PLC 摘要:The application pertains to a process for the synthesis of polyol fatty acid polyesters, in which a polyol and/or a fatty acid oligoester thereof, is esterified by reaction with fatty acid lower alkylester under substantially solvent-free conditions at elevated temperature in the presence of a transesterification catalyst and, optionally an emulsifier, and in which at least during the final stage of the transesterification reaction the reaction mixture is submitted to the action of a stripping agent suitable for accelerating the removal of the lower alkyl alcohol formed in said reaction. The process is of particular advantage in the synthesis of polyesters of very high degrees of conversion.
专利号:US-5939304-A 优先权日:1997-06-05 标题:Method for synthesis of anhydrothrombin 发明人:SUZUKI TOYOAKI; HOSOKAWA KAZUYA; NAGATA MASANORI 权利人:FUJIMORI KOGYO CO 摘要:A method for a synthesis of anhydrothrombin is provided which features a short process, an easy procedure, and high yields. n The method comprises n (A) a step of causing an active serine residue site of thrombin to react with an inhibitor, n (B) a step of performing an alkali treatment at a pH of not less than 11, and n (C) a step of performing an operation of recovery, and carries out these steps sequentially in the order mentioned, and is characterized by causing at least the step of performing the operation of recovery to proceed in the presence of at least one compound selected from the group consisting of polyhydric alcohols and saccharides, and a salt or an amphoteric electrolyte.
专利号:US-5945529-A 优先权日:1996-07-19 标题:Synthesis of polyol fatty acid polyesters using column with inert gas stripping 发明人:CORRIGAN PATRICK JOSEPH; KENNEALLY COREY JAMES; GRANBERG ERIC PAUL 权利人:PROCTER & GAMBLE 摘要:Processes for the synthesis of polyol fatty acid polyester by transesterification of a polyol comprise reacting polyol with a first portion of fatty acid lower alkyl ester to provide a first step reaction product in which substantially all of the polyol is reacted with at least one fatty acid lower alkyl ester. The processes then employ a multistage column providing substantial plug flow of liquid therein for further transesterification of the first step reaction product. Partially esterified polyol, a second portion of fatty acid lower alkyl ester and catalyst are fed to the column to form a mixture and cause further transesterification of the partially esterified polyol and fatty acid lower alkyl ester, with lower alkyl alcohol being formed as a by product. The resulting liquid mixture of reactants and product is passed in a first direction between adjacent stages through the column for further reaction of partially esterified polyol with fatty acid lower alkyl ester. An inert stripping or sparging gas is fed through the column in a second direction between adjacent stages, counter current to the flow of the liquid mixture between adjacent stages in the first direction, with radial shear agitation. The lower alkyl alcohol by-product of the polyol-fatty acid lower alkyl ester reaction is transferred from the liquid mixture to the inert gas.
专利号:US-10973847-B2 优先权日:2017-06-30 标题 :Core-to-surface polymerization for the synthesis of star polymers and uses thereof 发明人:JOHNSON JEREMIAH A; GOLDER MATTHEW R 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:Disclosed are methods, compositions, reagents, systems, and kits to prepare star polymers, as well as compositions and uses thereof. Various embodiments show that synthesis of these polymers contain low metal concentration to provide polymers for diverse biomedical applications including in vivo applications.
摘要:Clapés, P.; Fessner, W.-D., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 715. 摘要:Faber, K.; Glueck, S. M., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 1, 464. 摘要:Faber, K.; Glueck, S. M., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 1, 461. 摘要:Clapés, P., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 2, 63. 摘要:Faber, K.; Glueck, S. M., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 1, 455.