CAS: 551-84-8; (3S,4R)-1,3,4,5-Tetrahydroxypentan-2-One

该化合物是氯开蓬塔糖D-xyluloes的一种高纯净水溶液,通常用于生化和酶研究;这种现用配方可确保持续集中,消除耗时准备的需要;这种配方适合于涉及碳水化合物新陈代谢的研究,钢糖磷酸盐途径调查,酶动能学研究,特别是Xyllulomolase和转口体;其水体形式可提高溶解性和稳定性,减少固体阶段试剂的处理风险;标准化的浓度(0.5M)有利于可复制的实验条件,使其适合高通量的化验和代谢特征分析;固化过滤和严格的质量控制确保成百分批到批的变异性,以取得可靠的结果.

结构式图片

相似化合物

2042-27-5 7643-75-6 87-99-0

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CAS号645417-20-5 5-O-tetrahydrop... | CAS号19694-88-3 D-threo-Pentosulose | CAS号488-84-6 D-核酮糖 | CAS号58-86-6 D-木糖 | CAS号1113-60-6 羟基丙酮酸 | CAS号56-82-6 DL-甘油醛 | CAS号96-26-4 1,3-二羟基丙酮 | CAS号141-46-8 羟乙醛 | CAS号58-86-6 D-木糖 | CAS号10323-20-3 D-阿拉伯糖 | CAS号50-69-1 核糖 | CAS号20881-04-3 双丙酮-D-木糖 | CAS号87-99-0 木糖醇 | CAS号189328-24-3 (3R,4S,5R)-3,4-...

合成工艺路线路线简述

  • 141-46-8 + 96-26-4 = 551-84-8 + 95-43-2
    反应条件:1.1 Catalysts: Fructose-6-Phosphate Aldolase
    标题:Engineering The Donor Selectivity Of D-Fructose-6-Phosphate Aldolase For Biocatalytic Asymmetric Cross-Aldol Additions Of Glycolaldehyde
    作者:Szekrenyi,Anna; Soler,Anna; Garrabou,Xavier; Guerard-Helaine,Christine; Parella,Teodor; Et Al
    参考文献:Chemistry - A European Journal 日期:2014 卷标:20(39) 页码:12572-12583
📜D-来苏糖置于recombinant Thermosediminibacter oceani Dsm 16646 D-Lyxose Isomerase,Manganese(Ll) Chloride体系中,用 Aq. Phosphate Buffer 作为反应溶剂,化学反应生成 D-木酮糖
参考文献:来自海洋嗜热微杆菌的热稳定 D-来苏糖异构酶将 D-果糖高效生物转化为 D-甘露糖
标题:来自海洋嗜热微杆菌的热稳定 D-来苏糖异构酶将 D-果糖高效生物转化为 D-甘露糖
摘要:摘要 D-甘露糖具有益生元作用和潜在的医学应用.此外,它还可以作为底物生产甘露醇,一种广泛用于食品工业的功能性多元醇.由于这一结果,它引起了许多研究人员的关注.在这项工作中,一种热稳定的 D-甘露糖产生 D-来苏糖异构酶 (D-Li) 来自超嗜热菌,Thermosediminibacteroceani.mn 2+ 可显着激活重组d-Li.在 Ph 6.5 和 65 oc 下,它在 1 Mm Mn 2+ 存在下表现出最大活性,并被确定在 80 oc 下具有高度的热稳定性.在 70,75,80 和 85 oc 下计算的半衰期分别为 5.64,2.82,0.77 和 0.2 小时.该酶以d-来苏糖为底物表现出最佳活性,并能有效催化d-果糖和d-甘露糖之间的异构化.
DOI:10.1016/j.Procbio.2016.08.023

海关参考信息

专利信息


专利号:US-2022395800-A1
优先权日:2019-11-04
标题:Device for automated synthesis of oligo- and polysaccharides
发明人:SEEBERGER PETER H; DANGLAD FLORES JOSE; LE MAI HOANG KIM; PARDO VARGAS ALONSO; SLETTEN ERIC; SALWICZEK MARIO
权利人:MAX PLANCK GESELLSCHAT ZU RFERDERUNG DER WSS E V; GlycoUniverse GmbH & Co KG&A
摘要:The present invention generally relates to automated synthesis technology, and more particularly, to a device and method for automated synthesis of oligo- and polysaccharides on a solid support. In particular the present invention relates to a device for automated synthesis of oligo- and polysaccharides on a solid support comprising a reaction vessel, a reagent storing component, a reagent delivery system, a cooling device for cooling reaction vessel, and a pre-cooling device for pre-cooling the reagents to be supplied.

专利号:US-2019315790-A1
优先权日:2016-11-11
标题:Synthesis of d-allulose
发明人:KOCH TIMO JOHANNES; KIPPING FLORIAN; BUTZ STEFFEN; LESCH MARCEL; HÄSSLER THOMAS
权利人:PFEIFER & LANGEN GMBH & CO KG
摘要:The invention relates to a process for the synthesis of a product saccharide, preferably of D-allulose from an educt saccharide, preferably from D-fructose under heterogeneous or homogeneous catalysis which includes chemical and/or enzymatic catalysis. The synthesis is performed in at least two reactors that are arranged in series and the reaction product exiting the first reactor is subjected to chromatographic separation before it enters the second reactor. Preferably, the chromatographic separation is integrated in a simulated moving bed.

专利号:EP-0349059-B1
优先权日:1988-06-29
标题:Process for the synthesis of polyol fatty acid polyesters
发明人:WILLEMSE GERARDUS W
权利人:UNILEVER NV; UNILEVER PLC
摘要:The application pertains to a process for the synthesis of polyol fatty acid polyesters, in which a polyol and/or a fatty acid oligoester thereof, is esterified by reaction with fatty acid lower alkylester under substantially solvent-free conditions at elevated temperature in the presence of a transesterification catalyst and, optionally an emulsifier, and in which at least during the final stage of the transesterification reaction the reaction mixture is submitted to the action of a stripping agent suitable for accelerating the removal of the lower alkyl alcohol formed in said reaction. The process is of particular advantage in the synthesis of polyesters of very high degrees of conversion.

专利号:US-5939304-A
优先权日:1997-06-05
标题:Method for synthesis of anhydrothrombin
发明人:SUZUKI TOYOAKI; HOSOKAWA KAZUYA; NAGATA MASANORI
权利人:FUJIMORI KOGYO CO
摘要:A method for a synthesis of anhydrothrombin is provided which features a short process, an easy procedure, and high yields. n The method comprises n (A) a step of causing an active serine residue site of thrombin to react with an inhibitor, n (B) a step of performing an alkali treatment at a pH of not less than 11, and n (C) a step of performing an operation of recovery, and carries out these steps sequentially in the order mentioned, and is characterized by causing at least the step of performing the operation of recovery to proceed in the presence of at least one compound selected from the group consisting of polyhydric alcohols and saccharides, and a salt or an amphoteric electrolyte.

专利号:US-5945529-A
优先权日:1996-07-19
标题:Synthesis of polyol fatty acid polyesters using column with inert gas stripping
发明人:CORRIGAN PATRICK JOSEPH; KENNEALLY COREY JAMES; GRANBERG ERIC PAUL
权利人:PROCTER & GAMBLE
摘要:Processes for the synthesis of polyol fatty acid polyester by transesterification of a polyol comprise reacting polyol with a first portion of fatty acid lower alkyl ester to provide a first step reaction product in which substantially all of the polyol is reacted with at least one fatty acid lower alkyl ester. The processes then employ a multistage column providing substantial plug flow of liquid therein for further transesterification of the first step reaction product. Partially esterified polyol, a second portion of fatty acid lower alkyl ester and catalyst are fed to the column to form a mixture and cause further transesterification of the partially esterified polyol and fatty acid lower alkyl ester, with lower alkyl alcohol being formed as a by product. The resulting liquid mixture of reactants and product is passed in a first direction between adjacent stages through the column for further reaction of partially esterified polyol with fatty acid lower alkyl ester. An inert stripping or sparging gas is fed through the column in a second direction between adjacent stages, counter current to the flow of the liquid mixture between adjacent stages in the first direction, with radial shear agitation. The lower alkyl alcohol by-product of the polyol-fatty acid lower alkyl ester reaction is transferred from the liquid mixture to the inert gas.

专利号:US-10973847-B2
优先权日:2017-06-30
标题 :Core-to-surface polymerization for the synthesis of star polymers and uses thereof
发明人:JOHNSON JEREMIAH A; GOLDER MATTHEW R
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:Disclosed are methods, compositions, reagents, systems, and kits to prepare star polymers, as well as compositions and uses thereof. Various embodiments show that synthesis of these polymers contain low metal concentration to provide polymers for diverse biomedical applications including in vivo applications.

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✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Clapés, P.; Fessner, W.-D., Science of Synthesis: Stereoselective Synthesis, (2011) 2, 715.
摘要:Faber, K.; Glueck, S. M., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 1, 464.
摘要:Faber, K.; Glueck, S. M., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 1, 461.
摘要:Clapés, P., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 2, 63.
摘要:Faber, K.; Glueck, S. M., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 1, 455.
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