CAS: 3669-80-5; 11-Hydroxyundecanoic Acid

该化合物是一种脂肪酸,其特征是长碳链和11个碳位置上存在一个氢氧基化合物组,该化合物具有反映其结构的分子式,共由11个碳原子组成,其特性由氢氧(OH)功能组组成.该化合物一般是无色的,可粉黄黄色液体或固体,视温度和纯度而定.该氢氧基化合物组具有流体生物特性,比典型脂肪酸更易溶于极地溶剂中.该化合物在各种应用中都有意义,包括表面活性剂,乳化剂和其他化学中间体的合成.此外,该化合物的独特结构允许在生物兼容材料和药物中的潜在用途.该氢氧基化合物组的存在也可影响其再活性,使之适合进一步的化学修改.

结构式图片

相似化合物

1852-04-6 765-04-8 3927-60-4

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上下游产品

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合成工艺路线路线简述

  • 合成目标产物 11-Hydroxyundecanoic Acid 主要起始原料 11-Bromoundecanoic Acid
  • (文献来源)合成步骤主要原料 11-Bromoundecanoic Acid
10-烯酸甲酯 反应生成11-羟基十一烷酸
参考文献:Electroorganic Synthesis. 65. Anodic Homocoupling Of Carboxylic Acids Derived From Fatty Acids.
标题:Electroorganic Synthesis. 65. Anodic Homocoupling Of Carboxylic Acids Derived From Fatty Acids.
摘要:Fatty Acid Derived Carboxylic Acids With Double Bonds,Hydroxy-,Amino-,Keto-,Ester-And Epoxy Groups Are Anodically Coupled To Dimers (Kolbe Electrolysis) In 29 To 81% Yield And Up To A 2.5 Mol Scale. Problems Due To The Low Conductivity Of Fatty Acid Salts Were Overcome By The Use Of A How Cell With A Narrow Electrode Gap. Fatty Acids With Branched Alkyl Chains Gave Dimers With Interesting Emulsifying Properties. Dimethyl Hexadecanedioate,Accessible From Methyl Azelate,Could Be Cyclized And Further Converted Into Homomuscone And Muscone In A Few Steps. A Commercial Mixture Of Dimeric Fatty Acids (C-36-Dicarboxylic Acids) Has Been Coupled To Give C-70-Diesters.
Doi:10.3891/acta.Chem.Scand.52-0672

海关参考信息

专利信息


专利号:US-2023111600-A1
优先权日:2019-12-17
标题 :Polymeric fatty acid compounds for the treatment of fibrous amino acid-based substrates, especially hair
发明人:WAGNER ROLAND; STREICHER KATHARINA; ROHMANN LAURA; WENSKE CHRISTIAN; HAVELI SHRUTISAGAR DATTATRAYA
权利人:MOMENTIVE PERFORMANCE MAT GMBH
摘要:The present invention is directed at mono-, di- or polyquaternary ammonium compounds of the formula (I) wherein x is 1 to 50, and F can be the same or different and is represented by the general formula (II) wherein at least one of the optionally substituted and optionally functional-group-containing hydrocarbon radicals R 1 , R 2 , R 3 , R 4 or R 5 contains at least one estolide moiety comprising two or more ester or amide moieties. The invention also relates to a process for the synthesis of such compounds, the use of the compounds in cosmetic formulations for skin and hair care, cosmetic compositions for the treatment of fibers, and compositions containing one or more of the compounds for the treatment of hair.

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人:MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-8138272-B2
优先权日:2006-05-22
标 题:Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
发明人:KONRADI ANDREI W; SMITH JENIFER L
权利人:KONRADI ANDREI W; SMITH JENIFER L; ELAN PHARM INC
摘要:This invention provides an improved synthesis of polymer conjugates of formula (I), n nof agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobuâ€? or related reaction conditions.

专利号:US-5502226-A
优先权日:1994-11-14
标 题:Process of preparing ω-hydroxy acids
发明人:CHO SUK H; DEFLORIO VICTOR
权利人:ARDEN ELIZABETH CO
摘要:A new synthesis of omega -hydroxy acids, which employs commercially available starting materials and lowers the cost of production. The process involves coupling a fatty acyl group by enamine chemistry, followed by a ring expansion and selective reduction of ketoacid.

专利号:US-8329854-B2
优先权日:2010-09-27
标题 :Synthesis of tri-component resins
发明人:BIRAU MARIA; ALLEN C GEOFFREY
权利人:BIRAU MARIA; ALLEN C GEOFFREY; XEROX CORP
摘要:A resinous compound of the formulas or a salt thereof, wherein G1 is —X1C(O)OR1, —X2OC(O)R2, or —X2OH; G2 is R4, R12, —C(O)R2, —C(O)X1C(O)OR1, or —C(O)X2OC(O)R2; R1 is an alkyl having from 10 to 80 carbon atoms; R2 is an alkyl having from 2 to 40 carbon atoms; each R3 and R4 is independently hydrogen, alkyl, arylalkyl or alkylaryl; each R5 and each R6 is independently hydrogen or alkyl; X1 and X2 are both a straight or branched alkylene group; t1 is 1 to 20; t2 and t3 is independently 0 to 20; u1 is 1 to 30; u2 and u3 is independently 0 to 30; each R7 and each R8 is independently hydrogen, alkyl, or alkoxyl; each R9 and each R10 is independently hydrogen, alkyl, or alkoxyl; Ar is a substituted or unsubstituted aromatic moiety; p is 1 to 5; q is 1 to 12; A⊖ is selected from the group consisting of Cl−, Br−, I−, HSO4−, HSO3−, CH3SO3−, NO3−, HCOO−, CH3COO−, H2PO4−, SCN−, BF4−, ClO4−, SSO3−, PF6−, and SbCl6−; and J is alkyl, arylalkyl, or alkylaryl.

专利号:US-7973193-B2
优先权日:2003-10-02
标题:Method for producing ester condensed product
发明人:ISHIHARA KAZUAKI; YAMAMOTO HISASHI
权利人:JAPAN SCIENCE & TECH AGENCY
摘要:The present invention is to provide a method for preparing an ester condensate and a catalyst therefore; wherein the method enables synthesis of enormous amounts of ester condensates comprising a specific structure in good yield, by a reaction of carboxylic acid and alcohol in equimolar amounts, while generation of by-products is prevented; wherein the catalyst exhibits good catalytic efficiency as a catalyst for use, the use of the catalyst in small amount is sufficient, and the catalyst is reusable and can be used repeatedly; therefore, the method for preparing an ester condensate of the present invention and the catalyst therefore can be applied to industrial methods which are preferable in view of green chemistry. Esterification reaction is performed by using a catalyst comprising a zirconium(IV) compound and/or a hafnium(IV) compound and an iron compound and a gallium compound. It is preferable that the zirconium(IV) compound is a compound represented by Zr(OH) a (OR 1 ) b , wherein, R 1 represents an acyl group or an alkyl group, and each of a and b is 0 or any one of integers of 1 to 4 and the relationship of a+b=4 is satisfied, and a zirconium(IV) halide.
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合成参考文献


参考文献:10.1023/a:1015025609230
摘要:Tsibizova EV, Vodovozova EL, Mikhalev II, Molotkovskiĭ IuG. [The synthesis of new photoaffinity probes on the basis of ganglioside GM1]. Bioorg Khim. 2002 Mar;28(2):173–9. doi: 10.1023/a:1015025609230.
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