CAS: 2255-14-3; (2R,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl Dihydrogen Phosphate

相似化合物

59-56-3 262856-84-8 27251-84-9

上下游产品

dibenzyl (2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl) phosphate 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide Dibenzyl(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)phosphat Dibenzyl(β-D-glucopyranosyl)phosphat β-D-glucopyranosyl O-α-D-Glucopyranosyl-(1-3)-α,β-L-rhamnopyranose alpha-D-glucopyranose α-D-galactopyranosyl phosphate

📜Phosphoric Acid Tris-(Tetra-O-Acetyl-α-D-Galactopyranosyl Ester)置于盐酸体系中,化学反应生成半乳糖-1-磷酸
参考文献:Colowick,Journal Of Biological Chemistry,1938,Vol. 124,P. 557
标题:Colowick,Journal Of Biological Chemistry,1938,Vol. 124,P. 557

专利信息

专利号:US-2008145899-A1
优先权日:2004-09-17
标题 :Production of Oligosaccharides By Microorganisms
发明人：JOHNSON KARL; BYRNE NOEL J; DEFREES SHAWN
权利人:NEOSE TECHNOLOGIES INC
摘要:The present invention relates to the enzymatic synthesis of oligosaccharides, including sialylated product saccharides. In particular, it relates to the use of recombinant cells to take up low cost precursors such as glucose, pyruvate and N-actyl-glucosamine, and to synthesize activated sugar moieties that are used in oligosaccharide synthesis. The methods make possible the synthesis of many oligosaccharides using microorganisms and readily available, relatively inexpensive starting materials.

专利号:US-2002132320-A1
优先权日:2001-01-10
标题:Glycoconjugate synthesis using a pathway-engineered organism
发明人：WANG PENG GEORGE; CHEN XI; LIU ZIYE; ZHANG WEI
摘要:This invention relates to methods and compositions for the production of glycoconjugates. In particular, organisms are provided with at least one heterologous gene encoding an enzyme for regenerating a sugar nucleotide along with at least one glycosyltransterase. Such organisms are useful for the large-scale synthesis of glycoconjugates.

专利号:US-7906460-B2
优先权日:2000-12-13
标 题:Active-site engineering of nucleotidylyltransferases and general enzymatic methods for the synthesis of natural and “unnaturalâ€? UDP- and TDP-nucleotide sugars
发明人：THORSON JON; NIKILOV DIMITAR B
权利人:SLOAN KETTERING INST CANCER
摘要:The present invention provides mutant nucleotidylyl-transferases, such as E p , having altered substrate specificity; methods for their production; and methods of producing nucleotide sugars, which utilize these nucleotidylyl-transferases. The present invention also provides methods of synthesizing desired nucleotide sugars using natural and/or modified E p or other nucleotidyltransferases; and nucleotide sugars synthesized by the present methods. The present invention further provides new glycosyl phosphates, and methods for making them.

专利号:US-2024117398-A1
优先权日:2021-01-20
标 题:Production of oligosaccharides comprising ln3 as core structure in host cells
发明人：AESAERT SOFIE; BEAUPREZ JOERI; PETERS GERT; VERCAUTEREN ANNELIES
权利人:INBIOSE NV
摘要:Described is a method of producing an oligosaccharide comprising a lacto-N-triose (LN3; GlcNAc-beta1,3-Gal-beta1,4-Glc) as a core trisaccharide by cultivation with a genetically modified cell, as well as the genetically modified cell used in the method. The genetically modified cell comprises at least one nucleic acid sequence coding for a galactoside beta-1,3-N-acetylglucosaminyltransferase and a glycosyltransferase involved in the synthesis of an oligosaccharide comprising LN3 as a core trisaccharide and at least one nucleic acid sequence expressing a membrane protein. Furthermore, the present invention provides for a purification of the oligosaccharide comprising LN3 as a core trisaccharide from the cultivation.

专利号:US-2015361124-A1
优先权日:2013-01-22
标 题:Method for the solid-phase based synthesis of phosphate-bridged nucleoside conjugates
发明人：SARAC IVO; MEIER CHRIS
权利人:UNIVERSITÄT HAMBURG; UNIV HAMBURG
摘要:A method for producing phosphate-bridged nucleoside conjugates, in particular poly- or oligonucleosides. In the method, an immobilized cyclosaligenyl derivative of a nucleoside, nucleotide, poly- or oligonucleotide, poly- or oligonucleoside, or an analog thereof, is synthesized, and the subsequent reaction with a nucleophile yields the desired phosphate-bridged nucleoside conjugate, which may subsequently be released from the solid phase.

专利号:US-5770407-A
优先权日:1996-12-10
标题:Process for preparing nucleotide inhibitors of glycosyltransferases
发明人：WONG CHI-HUEY; HAYASHI TAKASHI
权利人:SCRIPPS RESEARCH INST
摘要:Nucleotide linked 2-deoxy-2-fluoroglycosides are employed as potent competitive inhibitors of glycosyltransferases. More particularly, uridine-5'-diphospho-2-deoxy-2-fluoro-galactose (UDP-2F-Gal), guanidine-5'-diphospho-2-deoxy-2-fluoro-L-fucose (GDP-2F-Fuc), uridine-51-diphospho-2-deoxy-2-fluoro-D-glucose (UDP-2F-Glu), guanosine-5'-diphospho-2-deoxy-2-fluoro-D-mannose (GDP-2F-Man), cytosine-5'-monophospho-2-deoxy-2-fluoro-D-sialic acid, and cytosine-5'-monophospho-2-deoxy-2-KDO may be employed as inhibitors of β-1,4-galactosyltransferase, α-1,3-fucosyltransferase, glucosyltransferases, N-acetylglucosaminyltransferases, (α-mannosyltransferases, α-sialyltransferases, and KDO-transferases, respectively. Synthesis of nucleotide-linked-2-deoxy-2-fluoroglycosides is achieved using either chemoenzymatic or chemical methodologies.