专利号:US-6972330-B2 优先权日:1996-02-13 标题:Chemical synthesis of methoxy nucleosides 发明人:BEIGELMAN LEONID; HAEBERLI PETER; KARPEISKY ALEXANDER; SWEEDLER DAVID 权利人:SIRNA THERAPEUTICS INC 摘要:Process for chemical synthesis of methoxy nucleosides.
专利号:US-4041067-A 优先权日:1976-07-21 标 题:Synthesis of oxalate esters by the oxidative carbonylation of amide acetals 发明人:ZEHNER LEE R; ZAJACEK JOHN G 权利人:ATLANTIC RICHFIELD CO 摘要:A process for the preparation of oxalate esters by the catalytic oxidative carbonylation of an amide acetal having the formula with carbon monoxide and oxygen or oxygen-containing gas in the presence of a metal salt catalyst, an amine base and a catalytic amount of an alcohol. Preferably a catalytic amount of particular oxidizing metal salts is employed along with a catalytic amount of an amine salt compound which may be formed in situ by the addition of an acid. Alternatively various counterions and ligands of the metal salt catalyst may be employed.
专利号:US-5962675-A 优先权日:1996-02-13 标 题:Chemical syntheses of 2'-O-methoxy purine nucleosides 发明人:BEIGELMAN LEONID; SWEEDLER DAVID; HAEBERLI PETER; KARPEISKY ALEXANDER 权利人:RIBOZYME PHARM INC 摘要:Several processes for the chemical synthesis of 2'-O-methoxy purine nucleosides are herein disclosed.
专利号:CA-2253382-A1 优先权日:1996-01-16 标题:Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules
专利号:WO-9726270-A2 优先权日:1996-01-16 标 题 :Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules
专利号:EP-0886641-A2 优先权日:1996-01-16 标 题 :Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules
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