CAS: 1918-16-7; Propachlor

该化合物是一种选择性除草剂,主要用于控制各种作物,特别是玉米和大豆的年青草和某些大叶杂草,属于氯乙酰胺除草剂的类别和功能,在早期发育阶段阻止杂草生长,其特点是在水中的溶解性相对较低,有助于其在土壤中的持久性和在杂草管理中的有效性,通常在杂草建立之前就使用抗生素前或早期出现后针对杂草.该化合物具有中度毒性特征,其环境影响是农业做法的一个考虑因素,需要遵守安全准则,以尽量减少对非目标生物和生态系统的潜在危险.此外,其化学结构包括一个氯化合物,这是其除草活动的组成部分.与所有农药一样,适当的处理和应用对于确保有效性,同时尽量减少对人类健康和环境的不利影响至关重要.

结构式图片

欧盟法规

《欧盟PIC法规》统一分类与标签"欧盟管控危险化学品"ECHA物质ECHA物质工作场所安全标识要求OtherC&L通报REACH预注册废弃物危险特性清单

上下游产品

CAS号768-52-5 N-异丙基苯胺 | CAS号79-04-9 氯乙酰氯 | CAS号768-52-5 N-异丙基苯胺 | CAS号10487-31-7 1-异丙基-1H-吲哚-2,3-二酮

合成工艺路线路线简述

    📜苯胺置于三乙胺体系中,用 二氯甲烷,乙腈 用作溶剂,化学反应 20.0H,反应生成毒草胺
    参考文献:Thioimidazoline Based Compounds Reverse Glucocorticoid Resistance In Human Acute Lymphoblastic Leukemia Xenografts
    标题:Thioimidazoline Based Compounds Reverse Glucocorticoid Resistance In Human Acute Lymphoblastic Leukemia Xenografts
    摘要:糖皮质激素是小儿急性淋巴细胞白血病化疗方案的重要组成部分,对糖皮质激素治疗的初次反应不佳预示着较差的预后.
    Doi:10.1039/c5Ob00779H

    海关参考信息

    专利信息


    专利号:WO-2024256370-A1
    优先权日:2023-06-13
    标 题 :Synthesis of glufosinate using an amidase-based process
    发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

    专利号:US-2025120400-A1
    优先权日:2021-12-10
    标题:Synthesis of glufosinate using a hydantoinase-based process
    发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

    专利号:US-11919928-B2
    优先权日:2016-03-16
    标题 :Method for producing dihydrotentoxin
    发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
    权利人:KUMIAI CHEMICAL INDUSTRY CO
    摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

    专利号:US-2021386068-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

    专利号:US-2021352899-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.

    专利号:ES-2717283-T3
    优先权日:2012-07-24
    标 题:Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6- (4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and herbicides inhibitors of VLCFA synthesis and synthesis of fatty acids / lipids

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Quanrud GM, Lyu Z, Balamurugan SV, Canizal C, Wu HT, Genereux JC. Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles. ACS Chem Biol. 2023 Jul 21;18(7):1661-1676. doi: 10.1021/acschembio.3c00338. Epub 2023 Jul 10.
    2: Tresnakova N, Impellitteri F, Famulari S, Porretti M, Filice M, Caferro A, Savoca S, D Iglio C, Imbrogno S, Albergamo A, Vazzana I, Stara A, Di Bella G, Velisek J, Faggio C. Fitness assessment of Mytilus galloprovincialis Lamarck, 1819 after exposure to herbicide metabolite propachlor ESA. Environ Pollut. 2023 Aug 15;331(Pt 1):121878. doi: 10.1016/j.envpol.2023.121878. Epub 2023 May 25. 58(5):379-388. doi: 10.1080/03601234.2023.2208995. Epub 2023 May 7. 8(5):4694-4702. doi: 10.1021/acsomega.2c06561.
    5: Yang Y, Ghatge S, Ko Y, Yoon Y, Ahn JH, Kim JJ, Hur HG. Non-specific degradation of chloroacetanilide herbicides by glucose oxidase supported Bio- Fenton reaction. Chemosphere. 2022 Apr;292:133417. doi: 10.1016/j.chemosphere.2021.133417. Epub 2021 Dec 23. 44(22):4151-4166. doi: 10.1002/jssc.202100551. Epub 2021 Sep 22. 22(13):6876. doi: 10.3390/ijms22136876.

    合成参考文献


    摘要:World Review of Pest Control., 9(119), 1970
    摘要:Eksperimentalna Meditsina i Morfologiya., 13(123), 1974
    摘要:Environmental Health Criteria 147: Propachlor pp. 13-18 (1993) by the International Programme on Chemical Safety (IPCS) under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation and the World Health Organization.
    摘要:U.S. Environmental Protection Agency/Office of Prevention, Pesticides, and Toxic Substances. Reigart, J.R., Roberts, J.R. Recognition and Management of Pesticide Poisonings. 5th ed. 1999. EPA Document No. EPA 735-R-98-003, and available in electronic format at:
    摘要:USEPA/Office of Water; Federal-State Toxicology and Risk Analysis Committee (FSTRAC). Summary of State and Federal Drinking Water Standards and Guidelines (11/93) To Present
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